Cell screen for vaccine candidate discovery

This invention relates to a novel screening process for detecting genes from harmful bacteria that produce factors involved in infection and are potential vaccine candidates.

A library of protein expression is generated and screened against human macrophages to identify potential vaccine targets.

Key benefits

High throughput techniques will help to identify new vaccine targets quickly.

Immunogenic targets are easily identified and cloned for the purpose of generating vaccine antigens.

Applications

The invention can be used as a tool to rapidly identify strong targets for vaccine candidate development for anti-macrophage micro-organisms.

It can also be used as a method of developing strong diagnostic tools for bacterial identification.

IP status

A US patent exists for this technology (61/473,395)

Commercial opportunity

This technology is available as an Easy Access licence deal to companies and individuals.

For more information please email Mark Kelly or phone 01392 722364.