The Halpin Laboratory
The Halpin Laboratory
The Halpin Laboratory
The Halpin Laboratory

The Halpin Laboratory

The Halpin Laboratory is a large open-plan containment level 2 laboratory in the Geoffrey Pope Building capable of housing up to 50 researchers. We share this state-of-the-art laboratory, which opened in 2007, with the research groups of Prof. Sarah Gurr, Professor of Food Security, Dr Chris Thornton, an immunologist who works on pathogenic fungi and rhizosphere biology, and Dr Panagiotis Sarris. We all share common interests in the molecular basis of plant disease and how plants resist infections.

Walk-in growth chambers are available for rice cultivation and propagation of Magnaporthe oryzae and the laboratory is well equipped for molecular genetics, protein biochemistry and genomics research. We have access to a glasshouse complex for transgenic rice cultivation which opened in 2010.

Robotic workstations are available for DNA extraction and high throughput preparation of PCR/DNA sequencing reactions. The laboratory is linked to a second large, open-plan laboratory which houses the groups of Prof. Ken Haynes, Professor of Fungal Biology, Prof. Robert Beardmore, EPSRC Leadership Fellow in Mathematical Biosciences, Prof. Ivana Gudelj, Professor of Evolutionary Systems Biology, Dr Steve Bates and Dr Mark Ramsdale who study Candida albicans, Candida glabrata and Aspergillus fumigatus, Dr Bryony Williams who studies microsporidia and Dr Jamie Stevens an evolutionary parasitologist.

We also share facilities with Dr David Studholme who collaborates on bioinformatics. The School has excellent bio-imaging facilities under the direction of our close collaborator Prof. Gero Steinberg. We have access to a Jeol 1400 transmission electron microscope, Jeol scanning electron microscope, Zeiss laser confocal microscope and Olympus/Visitron laser excitation epifluorescence microscopes. We also have an Olympus laser excitation epifluorescence microscope and a Leica fluorescence stereo microscope. Proteomics and metabolomics facilities (Agilent Triple Quad Q-ToF-MS) are also available in the School and extensive bioinformatics infrastructure is in place. Our School houses an Illumina HiSeq2500 next generation DNA sequencer, which we are using in comparative genomics experiments with M. oryzae.

This facility is supported by the Wellcome Trust Biomedical Informatics Hub.