Research projects and PhDs

Systems Biology research at the University of Exeter is based on a broad and inclusive view, and encompasses diverse approaches and model systems to answer key biological questions. These include all levels of biological organisation from molecular networks to organisms to ecosystems.

The table below details our current funded research projects and PhD projects.

Current funded research projects
Current PhD projects
Title Elucidating signalling networks in plant stress responses (SABR)
Principal Investigator Professor Murray Grant
Funding body  BBSRC
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Title Systemic plant immunity: identification of long distance signalling components & responses involved in plant defence
Candidate  Siddharth Jayaraman
First supervisor Professor Murray Grant
Second supervisor Professor Trevor Bailey
Title Investigating the biology of appressorium-mediated plant infection by the rice blast fungus magnaorthe grisea
Principal Investigator Professor Nick Talbot
Funding body  BBSRC
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Title Systems analysis of calmodium signalling in circadian clock function & photoperiodism in Arabidopsis thaliana
Candidate Elanor Witterick
First supervisor Dr John Love
Second supervisor  Dr Ozgur Akman
Title The control of ascorbate biosynthesis: the role of light & GDP-P-galactose phosphorylase
Principal Investigator Professor Nick Smirnoff
Funding body
  BBSRC
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Title The plant apoplastic frontier
Candidate Choon Kiat Lim
First supervisor Professor Nick Smirnoff
Second supervisor Professor Murray Grant
Title Transgenerational effects and evolution
Principal Investigator Professor Stuart Townley
Funding body
EPSRC
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Title Modelling bi-directional long-distance organelle transport in Ustilago maydis
Candidate Congping Lin
First supervisor Professor Peter Ashwin
Second supervisor Professor Gero Steinberg
Title Synthetic integrons for continuous directed evolution of complex genetic ensembles
Principal Investigator Professor Declan Bates
Funding body
EPSRC
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Title Whole genome sequencing & comparative genomics of clinically relevant Clostridium difficile isotopes
Candidate  Emma Butt
First supervisor Dr Steve Michell
Second supervisor  Dr Ed Keedwell
Title Post-transcriptional feedback control of polyamine metabolism in yeast: an integrated modelling and experimental investigation
Principal Investigator Professor Declan Bates
Funding body BBSRC
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Title Endocrine disruption & human health: a genome wide study of mechanisms & pathways
Candidate  Ricardo Copelli
First supervisor Professor Tamara Galloway
Second supervisor Dr Ed Keedwell
Title Preventing ventilator associated lung injury using feedback control engineering
Principal Investigator Professor Declan Bates
Funding body  EPSRC
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Title Bioinformatics of next generation sequencing approaches: using 454 & solexa data to look at insect genomes & transcriptomes
Candidate  Ritika Chauhan
Biosciences supervisor Professor Richard Ffrench-Constant
CEMPS supervisor  Dr Jamie Stevens / Dr David Studholme
Title Analysis of biochemical networks using robust control theory
Principal Investigator Professor Declan Bates
Funding body  BBSRC
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Title Response dynamics and evolution in signalling networks regulating bacterial chemotaxis
Candidate  Munia Amin
First supervisor Dr Orkun Soyer
Second supervisor  Dr Steve Porter
Title Engineering a semi-biotic immune system
Principal Investigator Dr Orkun Soyer
Funding body  EPSRC
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Title Boom or bust? Transient dynamics in stage structured biological systems
Candidate  Ian Stott
First supervisor Dr Dave Hodgson
Second supervisor Professor Stuart Townley
Title CARDIS: Chemical exposure and risk of cardiovascular disease in adults
Principal Investigator Professor Tamara Galloway
Funding body British Heart Foundation
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Title Understanding control of receptor tyrosine kinase signalling in endothelial cells using systems and synthetic biology
Candidate Deborah Alawo
First supervisor Professor Declan Bates
Seccond supervisor Professor Nick Brindle (University of Leicester)
Title Combinatorial responses of fungal pathogens to their human hosts: an integrative systems biology approach
Principal Investigator Professor Ken Haynes
Funding body BBSRC
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Title Robustness analysis of physiological simulators
Candidate Anup Das
First supervisor Professor Declan Bates
Second supervisor Dr Jonathan Hardman (University of Nottingham)


Title Characterisation of Interaction Partners of Secreted Nosema ceranae Proteins.
Candidate Marta Lalik
First supervisor Professor Ken Haynes
Second supervisor Dr Orkun Soyer / Dr Bryony Williams
  Title Modelling Redox Regulation in Saccharomyces and Candida glabrata
Candidate Suhaib Mohammed
First supervisor
Professor Ken Haynes
Second supervisor Professor Declan Bates / Professor Douglas Murray (Keio University, Japan)