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Isca research papers

Journal articles

Evans BD, Słowiński P, Hattersley AT, Jones SE, Sharp S, Kimmitt RA, Weedon MN, Oram RA, Tsaneva-Atanasova K, Thomas NJ, et al (2021). Estimating disease prevalence in large datasets using genetic risk scores. Nature Communications, 12(1)  Abstract. DOI.
Ruth KS, Day FR, Hussain J, Martínez-Marchal A, Aiken CE, Azad A, Thompson DJ, Knoblochova L, Abe H, Tarry-Adkins JL, et al (2021). Genetic insights into biological mechanisms governing human ovarian ageing. Nature, 596(7872), 393-397.  Abstract.  Author URL. DOI.
Foo M, Bates DG, Akman OE (2020). A simplified modelling framework facilitates more complex representations of plant circadian clocks. PLoS Comput Biol, 16(3)  Abstract.  Author URL. DOI.
Kraus S, Kreplin A, Young AK, Bate MR, Monnier JD, Harries TJ, Avenhaus H, Kluska J, Laws ASE, Rich EA, et al (2020). A triple star system with a misaligned and warped circumstellar disk. shaped by disk tearing.   Abstract.  Author URL.
Cunliffe AM, McIntire CD, Boschetti F, Sauer KJ, Litvak M, Anderson K, Brazier RE (2020). Allometric Relationships for Predicting Aboveground Biomass and Sapwood Area of Oneseed Juniper (Juniperus monosperma) Trees. Frontiers in Plant Science, 11  Abstract.  Author URL. DOI.
De Franco E, Caswell R, Johnson MB, Wakeling MN, Zung A, Dũng VC, Bích Ngọc CT, Goonetilleke R, Vivanco Jury M, El-Khateeb M, et al (2020). De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction. Diabetes, 69(3), 477-483.  Abstract.  Author URL. DOI.
Pilling LC, Jones LC, Masoli JAH, Delgado J, Atkins JL, Bowden J, Fortinsky RH, Kuchel GA, Melzer D (2020). Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older. <scp>UK</scp>. Biobank Participants. Journal of the American Geriatrics Society, 69(2), 365-372. DOI.
Ireland LG, Zanni C, Matt SP, Pantolmos G (2020). Magnetic Braking of Accreting T Tauri Stars: Effects of Mass Accretion Rate, Rotation, and Dipolar Field Strength. Astrophysical Journal, 906(1)  Abstract. DOI.
Bending TJR, Dobbs CL, Bate MR (2020). Photoionising feedback in spiral arm molecular clouds.   Abstract.  Author URL.
Avramidis E, Lalik M, Akman OE (2020). SODECL. ACM Transactions on Mathematical Software, 46(3), 1-21.  Abstract. DOI.
Jones G, Pilling LC, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2020). Sarcopenia and Variation in the Human Leukocyte Antigen Complex. J Gerontol a Biol Sci Med Sci, 75(2), 301-308.  Abstract.  Author URL. DOI.
Kuo C-L, Joaquim M, Kuchel GA, Ferrucci L, Harries LW, Pilling LC, Melzer D (2020). The Longevity-Associated SH2B3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects. J Gerontol a Biol Sci Med Sci, 75(9), 1656-1662.  Abstract.  Author URL. DOI.
Ruth KS, Day FR, Tyrrell J, Thompson DJ, Wood AR, Mahajan A, Beaumont RN, Wittemans L, Martin S, Busch AS, et al (2020). Using human genetics to understand the disease impacts of testosterone in men and women. Nature Medicine, 26(2), 252-258. DOI.
Casanova F, Tyrrell J, Beaumont RN, Ji Y, Jones SE, Hattersley AT, Weedon MN, Murray A, Shore AC, Frayling TM, et al (2019). A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio. Hum Mol Genet, 28(24), 4197-4207.  Abstract.  Author URL. DOI.
Wright CF, West B, Tuke M, Jones SE, Patel K, Laver TW, Beaumont RN, Tyrrell J, Wood AR, Frayling TM, et al (2019). Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting. American Journal of Human Genetics, 104(2), 275-286.  Abstract. DOI.
Bewshea CM, Ahmad T, Kennedy N, Weedon M, Harrison J, Walker G, Goodhand J, Jones S (2019). Association of Genetic Variants in NUDT15 with Thiopurine-Induced Myelosuppression in Patients with Inflammatory Bowel Disease. JAMA - Journal of the American Medical Association, 321 (8), 773-785. DOI.
Thompson WD, Tyrrell J, Borges MC, Beaumont RN, Knight BA, Wood AR, Ring SM, Hattersley AT, Freathy RM, Lawlor DA, et al (2019). Association of maternal circulating 25(OH)D and calcium with birth weight: a mendelian randomisation analysis. PLoS Medicine, 16 DOI.
Słowiński P, Sheybani L, Michel CM, Richardson MP, Quairiaux C, Terry JR, Goodfellow M (2019). Background EEG connectivity captures the time-course of epileptogenesis in a mouse model of epilepsy. eneuro, ENEURO.0059-ENEU19.2019.  Abstract.  Author URL. DOI.
Lane JM, Jones SE, Dashti HS, Wood AR, Aragam KG, van Hees VT, Strand LB, Winsvold BS, Wang H, Bowden J, et al (2019). Biological and clinical insights from genetics of insomnia symptoms. Nature Genetics  Abstract. DOI.
Pilling L, Tamosauskaite J, Jones G, Wood A, Jones L, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2019). Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank. BMJ DOI.
Dobbs CL, Rosolowsky E, Pettitt AR, Braine J, Corbelli E, Sun J (2019). Comparing the properties of GMCs in M33 from simulations and observations. Monthly Notices of the Royal Astronomical Society, 485(4), 4997-5009.  Abstract. DOI.
Wurster J, Bate MR (2019). Disc formation and fragmentation using radiative non-ideal magnetohydrodynamics. Monthly Notices of the Royal Astronomical Society, 486(2), 2587-2603.  Abstract. DOI.
Debras F, Mayne N, Baraffe I, Goffrey T, Thuburn J (2019). Eigenvectors, Circulation and Linear Instabilities for Planetary Science. in 3 Dimensions (ECLIPS3D). A, 631  Abstract.  Author URL.
Goyal J, Mayne N, Sing D, Drummond B, Tremblin PLR, Amundsen DS, Evans T, Carter A, Spake J, Baraffe I, et al (2019). Erratum: a library of ATMO forward model transmission spectra for hot Jupiter exoplanets. MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 486(1), 783-795. DOI.
Budu-Aggrey A, Brumpton B, Tyrrell J, Watkins S, Modasli E, Celis-Morales C, Ferguson L, Vie G, Palmer T, Fritsche L, et al (2019). Evidence of a causal relationship between body mass index and psoriasis: a mendelian randomization study. PLoS Medicine DOI.
Bovijn J, Jackson L, Censin J, Chen CY, Laisk T, Laber S, Ferreira T, Pulit SL, Glastonbury CA, Smoller JW, et al (2019). GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology. American Journal of Human Genetics, 104(1), 157-163.  Abstract. DOI.
Alves AC, De Silva NMG, Karhunen V, Sovio U, Das S, Rob Taal H, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, et al (2019). GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Science Advances, 5(9)  Abstract. DOI.
Witherall L, Wagley S, Butler C, Tyler CR, Temperton B (2019). Genome Sequences of Four Vibrio parahaemolyticus Strains Isolated from the English Channel and the River Thames. Microbiol Resour Announc, 8(24)  Abstract.  Author URL. DOI.
Studholme DJ, Panda P, Sanfuentes Von Stowasser E, González M, Hill R, Sambles C, Grant M, Williams NM, McDougal RL (2019). Genome sequencing of oomycete isolates from Chile supports the New Zealand origin of Phytophthora kernoviae and makes available the first Nothophytophthora sp. genome. Mol Plant Pathol, 20(3), 423-431.  Abstract.  Author URL. DOI.
Green HD, Beaumont RN, Thomas A, Hamilton B, Wood AR, Sharp S, Jones SE, Tyrrell J, Walker G, Goodhand J, et al (2019). Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis. J Crohns Colitis, 13(12), 1578-1582.  Abstract.  Author URL. DOI.
Ji Y, Yiorkas AM, Frau F, Mook-Kanamori D, Staiger H, Thomas EL, Atabaki-Pasdar N, Campbell A, Tyrrell J, Jones SE, et al (2019). Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension. Diabetes, 68(1), 207-219.  Abstract.  Author URL. DOI.
Jones SE, Lane JM, Wood AR, van Hees VT, Tyrrell J, Beaumont RN, Jeffries AR, Dashti HS, Hillsdon M, Ruth KS, et al (2019). Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms. Nature Communications  Abstract. DOI.
Schafmayer C, Harrison JW, Buch S, Lange C, Reichert MC, Hofer P, Cossais F, Kupcinskas J, von Schönfels W, Schniewind B, et al (2019). Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms. Gut, 68(5), 854-865.  Abstract.  Author URL. DOI.
Wang H, Lane JM, Jones SE, Dashti HS, Ollila HM, Wood AR, van Hees VT, Brumpton B, Winsvold BS, Kantojärvi K, et al (2019). Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes. Nature Communications, 10(1)  Abstract. DOI.
Dashti HS, Jones SE, Wood AR, Lane JM, van Hees VT, Wang H, Rhodes JA, Song Y, Patel K, Anderson SG, et al (2019). Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. Nat Commun, 10(1)  Abstract.  Author URL. DOI.
Ruth KS, Soares ALG, Borges M-C, Eliassen AH, Hankinson SE, Jones ME, Kraft P, Nichols HB, Sandler DP, Schoemaker MJ, et al (2019). Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan. Hum Mol Genet, 28(8), 1392-1401.  Abstract.  Author URL. DOI.
Tamosauskaite J, Atkins J, Pilling L, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2019). Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants. Journals of Gerontology - Series a Biological Sciences and Medical Sciences
Richmond RC, Anderson EL, Dashti HS, Jones SE, Lane JM, Strand LB, Brumpton B, Rutter MK, Wood AR, Straif K, et al (2019). Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study. BMJ, 365  Abstract.  Author URL. DOI.
Manley R, Temperton B, Doyle T, Gates D, Hedges S, Boots M, Wilfert L (2019). Knock-on community impacts of a novel vector: spillover of emerging DWV-B from Varroa-infested honeybees to wild bumblebees. Ecol Lett, 22(8), 1306-1315.  Abstract.  Author URL. DOI.
Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, et al (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nat Genet, 51(5), 804-814.  Abstract.  Author URL. DOI.
Pulit SL, Stoneman C, Morris AP, Wood AR, Glastonbury CA, Tyrrell J, Yengo L, Ferreira T, Marouli E, Ji Y, et al (2019). Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. Hum Mol Genet, 28(1), 166-174.  Abstract.  Author URL. DOI.
Tuke MA, Ruth KS, Wood AR, Beaumont RN, Tyrrell J, Jones SE, Yaghootkar H, Turner CLS, Donohoe ME, Brooke AM, et al (2019). Mosaic Turner syndrome shows reduced penetrance in an adult population study. Genet Med, 21(4), 877-886.  Abstract.  Author URL. DOI.
Lines S, Mayne N, Manners J, Boutle I, Drummond B, Mikal-Evans T, Kohary K, Sing D (2019). Overcast on Osiris: 3D radiative-hydrodynamical simulations of a cloudy hot Jupiter using the parametrized, phase-equilibrium cloud formation code EDDYSED. Monthly Notices of the Royal Astronomical Society, 488, 1332-1355. DOI.
Young AK, Bate MR, Harries TJ, Acreman DM (2019). Synthetic molecular line observations of the first hydrostatic core from. chemical calculations.   Abstract.  Author URL.
Kuo C-L, Pilling LC, Kuchel GA, Ferrucci L, Melzer D (2019). Telomere length and aging-related outcomes in humans: a Mendelian randomization study in 261,000 older participants. Aging Cell, 18(6)  Abstract.  Author URL. DOI.
Kikas T, Rull K, Beaumont RN, Freathy RM, Laan M (2019). The Effect of Genetic Variation on the Placental Transcriptome in Humans. Frontiers in Genetics DOI.
Mayne NJ, Drummond B, Debras F, Jaupart E, Manners J, Boutle IA, Baraffe I, Kohary K (2019). The Limits of the Primitive Equations of Dynamics for Warm, Slowly Rotating Small Neptunes and Super Earths. Astrophysical Journal, 871(1)  Abstract. DOI.
Bate MR (2019). The statistical properties of stars and their dependence on metallicity. Monthly Notices of the Royal Astronomical Society, 484(2), 2341-2361.  Abstract. DOI.
Wurster J, Bate MR, Price DJ (2019). There is no magnetic braking catastrophe: Low-mass star cluster and protostellar disc formation with non-ideal magnetohydrodynamics. Monthly Notices of the Royal Astronomical Society, 489(2), 1719-1741.  Abstract. DOI.
Tyrrell J, Mulugeta A, Wood AR, Zhou A, Beaumont RN, Tuke MA, Jones SE, Ruth KS, Yaghootkar H, Sharp S, et al (2019). Using genetics to understand the causal influence of higher BMI on depression. Int J Epidemiol, 48(3), 834-848.  Abstract.  Author URL. DOI.
Liu X, Helenius D, Skotte L, Beaumont RN, Wielscher M, Geller F, Juodakis J, Mahajan A, Bradfield JP, Lin FTJ, et al (2019). Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Nat Commun, 10(1)  Abstract.  Author URL. DOI.
Bowman K, Jones L, Pilling LC, Delgado J, Kuchel GA, Ferrucci L, Fortinsky RH, Melzer D (2019). Vitamin D levels and risk of delirium: a mendelian randomization study in the UK Biobank. Neurology DOI.
Frayling TM (2018). A Common Allele in FGF21 Associated with Sugar Intake is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure. Cell Reports, 23(2), 327-336. DOI.
Nakato GV, Wicker E, Coutinho TA, Mahuku G, Studholme DJ (2018). A highly specific tool for identification of Xanthomonas vasicola pv. musacearum based on five Xvm-specific coding sequences. Heliyon, 4(12)  Abstract. DOI.
Goyal JM, Mayne N, Sing DK, Drummond B, Tremblin P, Amundsen DS, Evans T, Carter AL, Spake J, Baraffe I, et al (2018). A library of ATMO forward model transmission spectra for hot Jupiter exoplanets. MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 474(4), 5158-5185. DOI.
Kennedy P, Higginson AD, Radford AR, Sumner S (2018). Altruism in a volatile world. Nature DOI.
Pilling LC, Masoli J, Melzer D, Kuchel G (2018). Clinical Outcomes of CADASIL-Associated NOTCH3 Mutations in 451,424 European Ancestry Community Volunteers. Translational Stroke Research DOI.
Currie LK, Tobias SM (2018). Convection-driven kinematic dynamos with a self-consistent shear flow. Geophysical & Astrophysical Fluid Dynamics, 113(1-2), 131-148. DOI.
Michalopoulou VA, Vicente JG, Studholme DJ, Sarris PF (2018). Draft genome sequences of pathotype strains for three pathovars belonging to three xanthomonas species. Microbiology Resource Announcements, 7(12)  Abstract. DOI.
Schaum E, Buckling A, Studholme D, Smirnoff N, Yvon-Durocher G (2018). Environmental fluctuations accelerate molecular evolution of thermal tolerance in a marine diatom. Nature Communications DOI.
van Hees VT, Sabia S, Jones SE, Wood AR, Anderson KN, Kivimaki M, Frayling TM, Pack AI, Bucan M, Trenell MI, et al (2018). Estimating sleep parameters using an accelerometer without sleep diary. SCIENTIFIC REPORTS, 8 Author URL. DOI.
Jun G, Manning A, Almeida M, Zawistowski M, Wood AR, Teslovich TM, Fuchsberger C, Feng S, Cingolani P, Gaulton KJ, et al (2018). Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proc Natl Acad Sci U S A, 115(2), 379-384.  Abstract.  Author URL. DOI.
Lines S, Manners J, Mayne NJ, Goyal J, Carter AL, Boutle IA, Lee EKH, Helling C, Drummond B, Acreman DM, et al (2018). Exonephology: Transmission spectra from a 3D simulated cloudy atmosphere. of HD209458b.   Abstract.  Author URL.
Boutle IA, Mayne NJ, Drummond B, Manners J, Goyal J, Lambert FH, Acreman DM, Earnshaw PD (2018). Exploring the climate of Proxima B with the Met Office Unified Model (corrigendum). Astronomy and Astrophysics, 617 DOI.
Thomas NJ, Jones SE, Weedon MN, Shields BM, Oram RA, Hattersley AT (2018). Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank. The Lancet Diabetes and Endocrinology, 6(2), 122-129.  Abstract. DOI.
Yemataw Z, Muzemil S, Ambachew D, Tripathi L, Tesfaye K, Chala A, Farbos A, O'Neill P, Moore K, Grant M, et al (2018). Genome sequence data from 17 accessions of Ensete ventricosum, a staple food crop for millions in Ethiopia. Data in Brief, 18, 285-293.  Abstract. DOI.
Morcrette H, Morgan MS, Farbos A, O'Neill P, Moore K, Titball RW, Studholme DJ (2018). Genome sequence of Staphylococcus aureus Ex1, isolated from a patient with spinal osteomyelitis. Genome Announcements, 6(26)  Abstract. DOI.
Nielsen JB, Fritsche LG, Zhou W, Teslovich TM, Holmen OL, Gustafsson S, Gabrielsen ME, Schmidt EM, Beaumont R, Wolford BN, et al (2018). Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development. Am J Hum Genet, 102(1), 103-115.  Abstract.  Author URL. DOI.
Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, et al (2018). Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet, 27(4), 742-756.  Abstract.  Author URL. DOI.
Wurster J, Bate MR, Price DJ (2018). Hall effect-driven formation of gravitationally unstable discs in. magnetized molecular cloud cores.   Abstract.  Author URL.
Devran Z, Kahveci E, Hong Y, Studholme DJ, Tör M (2018). Identifying molecular markers suitable for Frl selection in tomato breeding. Theor Appl Genet, 131(10), 2099-2105.  Abstract.  Author URL. DOI.
Snowsill T, Yang H, Griffin E, Long L, Varley-Campbell J, Coelho H, Robinson S, Hyde C (2018). Low-dose computed tomography for lung cancer screening in high-risk populations: a systematic review and economic evaluation. Health Technology Assessment, 22(69), 1-276.  Abstract. DOI.
Yengo L, Sidorenko J, Kemper KE, Zheng Z, Wood AR, Weedon MN, Frayling TM, Hirschhorn J, Yang J, Visscher PM, et al (2018). Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry. Hum Mol Genet, 27(20), 3641-3649.  Abstract.  Author URL. DOI.
Minardi D, Studholme DJ, van der Giezen M, Pretto T, Oidtmann B (2018). New genotyping method for the causative agent of crayfish plague (Aphanomyces astaci) based on whole genome data. Journal of Invertebrate Pathology, 156, 6-13.  Abstract. DOI.
Drummond B, Mayne NJ, Manners J, Carter AL, Boutle IA, Baraffe I, Hebrard E, Tremblin P, Sing DK, Amundsen DS, et al (2018). Observable signatures of wind--driven chemistry with a fully consistent. three dimensional radiative hydrodynamics model of HD 209458b.   Abstract.  Author URL.
Wurster J, Bate MR, Price DJ (2018). On the origin of magnetic fields in stars.   Abstract.  Author URL.
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, et al (2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet, 50(1), 26-41.  Abstract.  Author URL. DOI.
Lines S, Mayne NJ, Boutle I, Manners J, Lee G, Helling C, Drummond B, Amundsen D, Goyal J, Acreman D, et al (2018). Simulating the cloudy atmospheres of HD 209458 b and HD 189733 b with the 3D Met Office Unified Model. Astronomy and Astrophysics DOI.
Dobbs CL, Pettitt AR, Corbelli E, Pringle JE (2018). Simulations of the flocculent spiral M33: what drives the spiral structure?. MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 478(3), 3793-3808. Author URL. DOI.
Jones MO, Bate MR (2018). Sink particle radiative feedback in smoothed particle hydrodynamics models of star formation. Monthly Notices of the Royal Astronomical Society DOI.
De Sanctis A, Amit I, Hepplestone S, Craciun M, Russo S (2018). Strain-engineered inverse charge-funnelling in layered semiconductors. Nature Communications, 9  Abstract. DOI.
Drummond B, Mayne NJ, Manners J, Baraffe I, Goyal J, Tremblin P, Sing DK, Kohary K (2018). The 3D Thermal, Dynamical, and Chemical Structure of the Atmosphere of HD 189733b: Implications of Wind-driven Chemistry for the Emission Phase Curve. Astrophysical Journal, 869(1)  Abstract. DOI.
Wurster JH, Bate MR, Price DJ (2018). The collapse of a molecular cloud core to stellar densities using radiation non-ideal magnetohydrodynamics. MNRAS, 475, 1859-1880. DOI.
Jones MO, Bate M (2018). The dependence of stellar properties on initial cloud density. Monthly Notices of the Royal Astronomical Society, 478, 2650-2662. DOI.
Mayne NJ, Drummond B, Baraffe I, Tremblin P, Manners J, Amundsen D, Goyal J, Acreman D (2018). The effect of metallicity on the atmospheres of exoplanets with fully coupled 3D hydrodynamics, equilibrium chemistry, and radiative transfer. Astronomy and Astrophysics
Higginson AD, Fawcett TW, Houston AI, McNamara JM (2018). Trust your gut: using physiological states as a source of information is almost as effective as optimal Bayesian learning. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 285(1871) Author URL. DOI.
Wood AR, Jonsson A, Jackson AU, Wang N, van Leewen N, Palmer ND, Kobes S, Deelen J, Boquete-Vilarino L, Paananen J, et al (2017). A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Diabetes, 66(8), 2296-2309.  Abstract.  Author URL. DOI.
Macé A, Tuke MA, Deelen P, Kristiansson K, Mattsson H, Nõukas M, Sapkota Y, Schick U, Porcu E, Rüeger S, et al (2017). CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nat Commun, 8(1)  Abstract.  Author URL. DOI.
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, et al (2017). Exome-wide association study of plasma lipids in >300,000 individuals. Nat Genet, 49(12), 1758-1766.  Abstract.  Author URL. DOI.
Pratt J, Baraffe I, Goffrey T, Constantino T, Viallet M, Popov MV, Walder R, Folini D (2017). Extreme value statistics for two-dimensional convective penetration in a pre-main sequence star. Astronomy and Astrophysics, 604  Abstract. DOI.
Hepplestone SP, Taylor NT, Davies F (2017). First principles electronic and elastic properties of fresnoite Ba2TiSi2O8. Materials Research Express, 4, 125904-125904.  Abstract. DOI.
Tyrrell J, Wood AR, Ames RM, Yaghootkar H, Beaumont RN, Jones SE, Tuke MA, Ruth KS, Freathy RM, Davey Smith G, et al (2017). Gene-obesogenic environment interactions in the UK Biobank study. Int J Epidemiol, 46(2), 559-575.  Abstract.  Author URL. DOI.
Sollars ESA, Harper AL, Kelly LJ, Sambles CM, Ramirez-Gonzalez RH, Swarbreck D, Kaithakottil G, Cooper ED, Uauy C, Havlickova L, et al (2017). Genome sequence and genetic diversity of European ash trees. Nature, 541(7636), 212-216.  Abstract.  Author URL. DOI.
Turner J, O'Neill P, Grant M, Mumford RA, Thwaites R, Studholme DJ (2017). Genome sequences of 12 isolates of the EU1 lineage of Phytophthora ramorum , a fungus-like pathogen that causes extensive damage and mortality to a wide range of trees and other plants. Genomics Data, 12, 17-21. DOI.
Pilling LC, Kuo C-L, Sicinski K, Tamosauskaite J, Kuchel GA, Harries LW, Herd P, Wallace R, Ferrucci L, Melzer D, et al (2017). Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Aging (Albany NY), 9(12), 2504-2520.  Abstract.  Author URL. DOI.
Baraffe I, Pratt J, Goffrey T, Constantino T, Folini D, Popov MV, Walder R, Viallet M (2017). Lithium Depletion in Solar-like Stars: Effect of Overshooting Based on Realistic Multi-dimensional Simulations. Astrophysical Journal Letters, 845(1)  Abstract. DOI.
Vicente JG, Rothwell S, Holub EB, Studholme DJ (2017). Pathogenic, phenotypic and molecular characterisation of Xanthomonas nasturtii sp. nov. and Xanthomonas floridensis sp. nov. new species of Xanthomonas associated with watercress production in Florida. Int J Syst Evol Microbiol, 67(9), 3645-3654.  Abstract.  Author URL. DOI.
Yaghootkar H, Bancks MP, Jones SE, McDaid A, Beaumont R, Donnelly L, Wood AR, Campbell A, Tyrrell J, Hocking LJ, et al (2017). Quantifying the extent to which index event biases influence large genetic association studies. Hum Mol Genet, 26(5), 1018-1030.  Abstract.  Author URL. DOI.
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, et al (2017). Rare and low-frequency coding variants alter human adult height. Nature, 542(7640), 186-190.  Abstract.  Author URL. DOI.
Pilling LC, Atkins JL, Duff MO, Beaumont RN, Jones SE, Tyrrell J, Kuo C-L, Ruth KS, Tuke MA, Yaghootkar H, et al (2017). Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. PLoS One, 12(9)  Abstract.  Author URL. DOI.
Goffrey T, Pratt J, Viallet M, Baraffe I, Popov MV, Walder R, Folini D, Geroux C, Constantino T (2016). Benchmarking the Multi-dimensional Stellar Implicit Code MUSIC.   Abstract.  Author URL.
Tyrrell J, Richmond RC, Palmer TM, Feenstra B, Rangarajan J, Metrustry S, Cavadino A, Paternoster L, Armstrong LL, De Silva NMG, et al (2016). Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA, 315(11), 1129-1129. DOI.
Yaghootkar H, Lotta LA, Tyrrell J, Smit RAJ, Jones SE, Donnelly L, Beaumont R, Campbell A, Tuke MA, Hayward C, et al (2016). Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease. Diabetes, 65(8), 2448-2460.  Abstract.  Author URL. DOI.
Ruth KS, Beaumont RN, Tyrrell J, Jones SE, Tuke MA, Yaghootkar H, Wood AR, Freathy RM, Weedon MN, Frayling TM, et al (2016). Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health. Hum Reprod, 31(2), 473-481.  Abstract.  Author URL. DOI.
Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, Van Zuydam NR, Gaulton KJ, Grarup N, et al (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 538(7624), 248-252.  Abstract. DOI.
Kilpeläinen TO, Carli JFM, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, et al (2016). Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nat Commun, 7  Abstract.  Author URL. DOI.
Pilling LC, Atkins JL, Bowman K, Jones SE, Tyrrell J, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Wood AR, et al (2016). Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. Aging (Albany NY), 8(3), 547-560.  Abstract.  Author URL. DOI.
Wood AR, Tyrrell J, Beaumont R, Jones SE, Tuke MA, Ruth KS, GIANT consortium, Yaghootkar H, Freathy RM, Murray A, et al (2016). Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. Diabetologia, 59(6), 1214-1221.  Abstract.  Author URL. DOI.
Usher CL, Handsaker RE, Esko T, Tuke MA, Weedon MN, Hastie AR, Cao H, Moon JE, Kashin S, Fuchsberger C, et al (2015). Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity. Nat Genet, 47(8), 921-925.  Abstract.  Author URL. DOI.

Conferences

Akman OE, Fieldsend JE (2020). Multi-objective optimisation of gene regulatory networks: Insights from a Boolean circadian clock model.  Abstract. DOI.
Smith RE, Pillai AC, Tabor G, Thies PR, Johanning L (2019). Impact of Rotor Misalignment Due to Platform Motions on Floating Offshore Wind Turbine Blade Loads. Proceedings of the International Conference on Offshore Mechanics and Arctic Engineering - OMAE2019. Glasgow, UK. 9th - 14th Jun 2019  Abstract.
Alyahya K, Akman O, Fieldsend JE (2019). Landscape Analysis Under Measurement Error. Genetic and Evolutionary Computation Conference Companion (GECCO). Prague, Czech Republic. 13th - 17th Jul 2019  Abstract. DOI.
Fieldsend JE, Doherty K, Alyahya K, Akman O (2019). Robust Optimisation using Voronoi-Based Archive Sampling. UQOP: Uncertainty Quantification & Optimization. Sorbonne University, Paris, France. 18th - 20th Mar 2019
Alyahya K, Doherty K, Akman O, Fieldsend JE (2018). Robust Multi-Modal Optimisation. Genetic and Evolutionary Computation Conference. Kyoto. 15th - 19th Jul 2018 DOI.
Doherty K, Alyahya K, Akman OE, Fieldsend JE (2017). Optimisation and Landscape Analysis of Computational Biology Models: a Case Study. Genetic and Evolutionary Computation Conference, Companion Proceedings. Berlin, Germany. 15th - 19th Jul 2017 DOI.
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