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Dr Marc Goodfellow

Dr Marc Goodfellow

Senior Lecturer in Mathematics

 3420

 +44 (0)1392 723420

 Living Systems Institute T05.10

 

Living Systems Institute, University of Exeter, Stocker Road, Exeter, EX4 4QD

Overview

I am a lecturer in Mathematics, member of the Systems Biomedicine group, affiliate of the Centre for Biomedical Modelling and Analysis and co-investigator of the EPSRC Centre for Predictive Modelling in Healthcare. My research is focussed on the development and use of mathematical and computational methods to help us understand the dynamics of complex biological systems, with a focus on problems in healthcare.

View my profile on the Mathematics website.

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Goodfellow M (In Press). Computational modelling in source space from scalp EEG to inform presurgical evaluation of epilepsy. Clinical Neurophysiology Full text.
Oza HB, Pandey R, Roper D, Al-Nuaimi Y, Spurgeon SK, Goodfellow M (In Press). Modelling and finite time stability analysis of psoriasis pathogenesis. International Journal of Control Full text.
Bick C, Goodfellow M, Laing CR, Martens EA (In Press). Understanding the dynamics of biological and neural oscillator networks. through mean-field reductions: a review.  Abstract.  Author URL.
Lopes M, Goodfellow M, Terry J (2019). A Model-Based Assessment of the Seizure Onset Zone Predictive Power to Inform the Epileptogenic Zone. Frontiers in Computational Neuroscience, 13 Full text.
Słowiński P, Sheybani L, Michel CM, Richardson MP, Quairiaux C, Terry JR, Goodfellow M (2019). Background EEG connectivity captures the time-course of epileptogenesis in a mouse model of epilepsy. eneuro, ENEURO.0059-ENEU19.2019. Abstract.  Author URL.  Full text.
Mohammadi H, Challenor P, Goodfellow M (2019). Emulating dynamic non-linear simulators using Gaussian processes. Computational Statistics and Data Analysis, 139, 178-196. Abstract.  Full text.
Tait L, Stothart G, Coulthard E, Brown JT, Kazanina N, Goodfellow M (2019). Network substrates of cognitive impairment in Alzheimer's Disease. Clin Neurophysiol, 130(9), 1581-1595. Abstract.  Author URL.  Full text.
Laiou P, Avramidis E, Lopes MA, Abela E, Müller M, Akman OE, Richardson MP, Rummel C, Schindler K, Goodfellow M, et al (2019). Quantification and Selection of Ictogenic Zones in Epilepsy Surgery. Frontiers in Neurology, 10 Abstract.  Full text.
Lopes MA, Perani S, Yaakub SN, Richardson MP, Goodfellow M, Terry JR (2019). Revealing epilepsy type using a computational analysis of interictal EEG. Sci Rep, 9(1). Abstract.  Author URL.  Full text.
Junges L, Lopes MA, Terry JR, Goodfellow M (2019). The role that choice of model plays in predictions for epilepsy surgery. Sci Rep, 9(1). Abstract.  Author URL.  Full text.
Ferrat LA, Goodfellow M, Terry JR (2018). Classifying dynamic transitions in high dimensional neural mass models: a random forest approach. PLoS Computational Biology, 14(3). Abstract.  Full text.
Tait L, Wedgwood K, Tsaneva-Atanasova K, Brown JT, Goodfellow M (2018). Control of clustered action potential firing in a mathematical model of entorhinal cortex stellate cells. J Theor Biol, 449, 23-34. Abstract.  Author URL.  Full text.
Lopes M, Richardson MP, Abela E, Rummel C, Schindler K, Goodfellow M, Terry J (2018). Elevated Ictal Brain Network Ictogenicity Enables Prediction of Optimal Seizure Control. Frontiers in Neurology, 9 Full text.
Müller M, Schindler K, Goodfellow M, Pollo C, Rummel C, Steimer A (2018). Evaluating resective surgery targets in epilepsy patients: a comparison of quantitative EEG methods. Journal of Neuroscience Methods, 305, 54-66. Abstract.  Full text.
Lopes MA, Richardson MP, Abela E, Rummel C, Schindler K, Goodfellow M, Terry JR (2017). An optimal strategy for epilepsy surgery: Disruption of the rich-club?. PLoS Comput Biol, 13(8). Abstract.  Author URL.  Full text.
Goodfellow M, Rummel C, Abela E, Richardson MP, Schindler K, Terry JR (2017). Computer models to inform epilepsy surgery strategies: Prediction of postoperative outcome. Brain, 140(5). Full text.
Jedynak M, Pons AJ, Garcia-Ojalvo J, Goodfellow M (2017). Temporally correlated fluctuations drive epileptiform dynamics. NeuroImage, 146, 188-196. Abstract.  Full text.
Schmidt H, Woldman W, Goodfellow M, Chowdhury FA, Koutroumanidis M, Jewell S, Richardson MP, Terry JR (2016). A computational biomarker of idiopathic generalized epilepsy from resting state EEG. Epilepsia Abstract.  Full text.
Booth CA, Ridler T, Murray TK, Ward MA, de Groot E, Goodfellow M, Phillips KG, Randall AD, Brown JT (2016). Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy. J Neurosci, 36(2), 312-324. Abstract.  Author URL.  Full text.
Goodfellow M, Rummel C, Abela E, Richardson MP, Schindler K, Terry JR (2016). Estimation of brain network ictogenicity predicts outcome from epilepsy surgery. Scientific Reports, 6, 29215-29215. Abstract.  Full text.
Stothart G, Petkov G, Kazanina N, Goodfellow M, Tait L, Brown J (2016). Graph-theoretical measures provide translational markers of large-scale brain network disruption in human dementia patients and animal models of dementia. International Journal of Psychophysiology, 108, 71-71.
Schindler K, Rummel C, Andrzejak RG, Goodfellow M, Zubler F, Abela E, Wiest R, Pollo C, Steimer A, Gast H, et al (2016). Ictal time-irreversible intracranial EEG signals as markers of the epileptogenic zone. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 127(9), 3051-3058. Abstract.  Full text.
Phillips NE, Manning CS, Pettini T, Biga V, Marinopoulou E, Stanley P, Boyd J, Bagnall J, Paszek P, Spiller DG, et al (2016). Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation. eLife, 5 Abstract.  Full text.
Taylor PN, Wang Y, Goodfellow M, Dauwels J, Moeller F, Stephani U, Baier G (2014). A computational study of stimulus driven epileptic seizure abatement. PLoS One, 9(12). Abstract.  Author URL.  Full text.
Petkov G, Goodfellow M, Richardson MP, Terry JR (2014). A critical role for network structure in seizure onset: a computational modeling approach. Front Neurol, 5 Abstract.  Author URL.  Full text.
Wang Y, Goodfellow M, Taylor PN, Baier G (2014). Dynamic mechanisms of neocortical focal seizure onset. PLoS Comput Biol, 10(8). Abstract.  Author URL.  Full text.
Müller MF, Rummel C, Goodfellow M, Schindler K (2014). Standing waves as an explanation for generic stationary correlation patterns in noninvasive EEG of focal onset seizures. Brain Connect, 4(2), 131-144. Abstract.  Author URL.
Goodfellow M, Phillips NE, Manning C, Galla T, Papalopulu N (2014). microRNA input into a neural ultradian oscillator controls emergence and timing of alternative cell states. Nat Commun, 5 Abstract.  Author URL.  Full text.
Rummel C, Goodfellow M, Gast H, Hauf M, Amor F, Stibal A, Mariani L, Wiest R, Schindler K (2013). A systems-level approach to human epileptic seizures. Neuroinformatics, 11(2), 159-173. Abstract.  Author URL.
Goodfellow M, Glendinning P (2013). Mechanisms of intermittent state transitions in a coupled heterogeneous oscillator model of epilepsy. J Math Neurosci, 3(1). Abstract.  Author URL.  Full text.
Taylor PN, Goodfellow M, Wang Y, Baier G (2013). Towards a large-scale model of patient-specific epileptic spike-wave discharges. Biol Cybern, 107(1), 83-94. Abstract.  Author URL.
Al-Nuaimi Y, Goodfellow M, Paus R, Baier G (2012). A prototypic mathematical model of the human hair cycle. J Theor Biol, 310, 143-159. Abstract.  Author URL.
Goodfellow M, Taylor PN, Wang Y, Garry DJ, Baier G (2012). Modelling the role of tissue heterogeneity in epileptic rhythms. Eur J Neurosci, 36(2), 2178-2187. Abstract.  Author URL.
Schindler K, Gast H, Goodfellow M, Rummel C (2012). On seeing the trees and the forest: single-signal and multisignal analysis of periictal intracranial EEG. Epilepsia, 53(9), 1658-1668. Abstract.  Author URL.
Wang Y, Goodfellow M, Taylor PN, Baier G (2012). Phase space approach for modeling of epileptic dynamics. Phys Rev E Stat Nonlin Soft Matter Phys, 85(6 Pt 1). Abstract.  Author URL.
Goodfellow M, Schindler K, Baier G (2012). Self-organised transients in a neural mass model of epileptogenic tissue dynamics. Neuroimage, 59(3), 2644-2660. Abstract.  Author URL.
Baier G, Goodfellow M, Taylor PN, Wang Y, Garry DJ (2012). The importance of modeling epileptic seizure dynamics as spatio-temporal patterns. Front Physiol, 3 Abstract.  Author URL.  Full text.
Goodfellow M, Schindler K, Baier G (2011). Intermittent spike-wave dynamics in a heterogeneous, spatially extended neural mass model. Neuroimage, 55(3), 920-932. Abstract.  Author URL.

Chapters

Wang Y, Goodfellow M, Taylor PN, Garry DJ, Baier G (2013). Computational modelling of microseizures and focal seizure onset. In  (Ed) Recent Advance in Predicting and Preventing Epileptic Sezures, 83-98.  Abstract.

Conferences

Lopes M, Richardson M, Abela E, Rummel C, Schindler K, Goodfellow M, Terry J (2018). A Computer Model Biomarker of Focal and Generalized Epilepsies from Resting State EEG.  Author URL.
Laiou P, Avramidis E, Lopes MA, Akman OE, Goodfellow M (2018). Estimating Seizure Freedom Post-Surgery Using Mathematical Modelling.  Author URL.
Jedynak M, Pons AJ, Garcia-Ojalvo J, Goodfellow M (2016). Identification of epileptogenic rhythms in a mesoscopic neuronal model.  Abstract.
Roper D, Al-nuaimi Y, Oza H, Goodfellow M, Spurgeon S (2014). A systems biological model of chronic plaque psoriasis captures dynamics of known treatments.  Author URL.
Baier G, Goodfellow M, Taylor PN, Wang Y, Garry DJ (2012). SPATIO-TEMPORAL MODELS TO PREDICT AND CONTROL EPILEPTIC SEIZURE DYNAMICS.  Author URL.
Baier G, Goodfellow M, Taylor P, Wang Y (2011). SPONTANEOUS SPIKE-WAVE DISCHARGES IN SPATIALLY EXTENDED MODELS OF EPILEPTIC DYNAMICS.  Author URL.

Reports

Mohammadi H, Challenor P, Goodfellow M, Williamson D (In Press). Emulating computer models with step-discontinuous outputs using Gaussian. processes. Abstract.  Author URL.  Full text.

Publications by year


In Press

Goodfellow M (In Press). Computational modelling in source space from scalp EEG to inform presurgical evaluation of epilepsy. Clinical Neurophysiology Full text.
Mohammadi H, Challenor P, Goodfellow M, Williamson D (In Press). Emulating computer models with step-discontinuous outputs using Gaussian. processes. Abstract.  Author URL.  Full text.
Oza HB, Pandey R, Roper D, Al-Nuaimi Y, Spurgeon SK, Goodfellow M (In Press). Modelling and finite time stability analysis of psoriasis pathogenesis. International Journal of Control Full text.
Bick C, Goodfellow M, Laing CR, Martens EA (In Press). Understanding the dynamics of biological and neural oscillator networks. through mean-field reductions: a review.  Abstract.  Author URL.

2019

Lopes M, Goodfellow M, Terry J (2019). A Model-Based Assessment of the Seizure Onset Zone Predictive Power to Inform the Epileptogenic Zone. Frontiers in Computational Neuroscience, 13 Full text.
Słowiński P, Sheybani L, Michel CM, Richardson MP, Quairiaux C, Terry JR, Goodfellow M (2019). Background EEG connectivity captures the time-course of epileptogenesis in a mouse model of epilepsy. eneuro, ENEURO.0059-ENEU19.2019. Abstract.  Author URL.  Full text.
Pinion J (2019). Concordant spatio-temporal patterns of brain activation in zebrafish exposed to compounds with similar pharmacodynamics or with similar seizurogenic potential.  Abstract.  Full text.
Mohammadi H, Challenor P, Goodfellow M (2019). Emulating dynamic non-linear simulators using Gaussian processes. Computational Statistics and Data Analysis, 139, 178-196. Abstract.  Full text.
Ferrat L (2019). Machine Learning and Statistical Analysis of Complex Mathematical Models: an Application to Epilepsy.  Abstract.  Full text.
Tait L (2019). Multi-Scale Mathematical Modelling of Brain Networks in Alzheimer's Disease.  Abstract.  Full text.
Tait L, Stothart G, Coulthard E, Brown JT, Kazanina N, Goodfellow M (2019). Network substrates of cognitive impairment in Alzheimer's Disease. Clin Neurophysiol, 130(9), 1581-1595. Abstract.  Author URL.  Full text.
Laiou P, Avramidis E, Lopes MA, Abela E, Müller M, Akman OE, Richardson MP, Rummel C, Schindler K, Goodfellow M, et al (2019). Quantification and Selection of Ictogenic Zones in Epilepsy Surgery. Frontiers in Neurology, 10 Abstract.  Full text.
Lopes MA, Perani S, Yaakub SN, Richardson MP, Goodfellow M, Terry JR (2019). Revealing epilepsy type using a computational analysis of interictal EEG. Sci Rep, 9(1). Abstract.  Author URL.  Full text.
Junges L, Lopes MA, Terry JR, Goodfellow M (2019). The role that choice of model plays in predictions for epilepsy surgery. Sci Rep, 9(1). Abstract.  Author URL.  Full text.

2018

Lopes M, Richardson M, Abela E, Rummel C, Schindler K, Goodfellow M, Terry J (2018). A Computer Model Biomarker of Focal and Generalized Epilepsies from Resting State EEG.  Author URL.
Ferrat LA, Goodfellow M, Terry JR (2018). Classifying dynamic transitions in high dimensional neural mass models: a random forest approach. PLoS Computational Biology, 14(3). Abstract.  Full text.
Tait L, Wedgwood K, Tsaneva-Atanasova K, Brown JT, Goodfellow M (2018). Control of clustered action potential firing in a mathematical model of entorhinal cortex stellate cells. J Theor Biol, 449, 23-34. Abstract.  Author URL.  Full text.
Lopes M, Richardson MP, Abela E, Rummel C, Schindler K, Goodfellow M, Terry J (2018). Elevated Ictal Brain Network Ictogenicity Enables Prediction of Optimal Seizure Control. Frontiers in Neurology, 9 Full text.
Laiou P, Avramidis E, Lopes MA, Akman OE, Goodfellow M (2018). Estimating Seizure Freedom Post-Surgery Using Mathematical Modelling.  Author URL.
Müller M, Schindler K, Goodfellow M, Pollo C, Rummel C, Steimer A (2018). Evaluating resective surgery targets in epilepsy patients: a comparison of quantitative EEG methods. Journal of Neuroscience Methods, 305, 54-66. Abstract.  Full text.

2017

Lopes MA, Richardson MP, Abela E, Rummel C, Schindler K, Goodfellow M, Terry JR (2017). An optimal strategy for epilepsy surgery: Disruption of the rich-club?. PLoS Comput Biol, 13(8). Abstract.  Author URL.  Full text.
Goodfellow M, Rummel C, Abela E, Richardson MP, Schindler K, Terry JR (2017). Computer models to inform epilepsy surgery strategies: Prediction of postoperative outcome. Brain, 140(5). Full text.
Jedynak M, Pons AJ, Garcia-Ojalvo J, Goodfellow M (2017). Temporally correlated fluctuations drive epileptiform dynamics. NeuroImage, 146, 188-196. Abstract.  Full text.

2016

Schmidt H, Woldman W, Goodfellow M, Chowdhury FA, Koutroumanidis M, Jewell S, Richardson MP, Terry JR (2016). A computational biomarker of idiopathic generalized epilepsy from resting state EEG. Epilepsia Abstract.  Full text.
Booth CA, Ridler T, Murray TK, Ward MA, de Groot E, Goodfellow M, Phillips KG, Randall AD, Brown JT (2016). Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy. J Neurosci, 36(2), 312-324. Abstract.  Author URL.  Full text.
Goodfellow M, Rummel C, Abela E, Richardson MP, Schindler K, Terry JR (2016). Estimation of brain network ictogenicity predicts outcome from epilepsy surgery. Scientific Reports, 6, 29215-29215. Abstract.  Full text.
Stothart G, Petkov G, Kazanina N, Goodfellow M, Tait L, Brown J (2016). Graph-theoretical measures provide translational markers of large-scale brain network disruption in human dementia patients and animal models of dementia. International Journal of Psychophysiology, 108, 71-71.
Schindler K, Rummel C, Andrzejak RG, Goodfellow M, Zubler F, Abela E, Wiest R, Pollo C, Steimer A, Gast H, et al (2016). Ictal time-irreversible intracranial EEG signals as markers of the epileptogenic zone. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 127(9), 3051-3058. Abstract.  Full text.
Jedynak M, Pons AJ, Garcia-Ojalvo J, Goodfellow M (2016). Identification of epileptogenic rhythms in a mesoscopic neuronal model.  Abstract.
Phillips NE, Manning CS, Pettini T, Biga V, Marinopoulou E, Stanley P, Boyd J, Bagnall J, Paszek P, Spiller DG, et al (2016). Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation. eLife, 5 Abstract.  Full text.

2014

Taylor PN, Wang Y, Goodfellow M, Dauwels J, Moeller F, Stephani U, Baier G (2014). A computational study of stimulus driven epileptic seizure abatement. PLoS One, 9(12). Abstract.  Author URL.  Full text.
Petkov G, Goodfellow M, Richardson MP, Terry JR (2014). A critical role for network structure in seizure onset: a computational modeling approach. Front Neurol, 5 Abstract.  Author URL.  Full text.
Roper D, Al-nuaimi Y, Oza H, Goodfellow M, Spurgeon S (2014). A systems biological model of chronic plaque psoriasis captures dynamics of known treatments.  Author URL.
Wang Y, Goodfellow M, Taylor PN, Baier G (2014). Dynamic mechanisms of neocortical focal seizure onset. PLoS Comput Biol, 10(8). Abstract.  Author URL.  Full text.
Müller MF, Rummel C, Goodfellow M, Schindler K (2014). Standing waves as an explanation for generic stationary correlation patterns in noninvasive EEG of focal onset seizures. Brain Connect, 4(2), 131-144. Abstract.  Author URL.
Goodfellow M, Phillips NE, Manning C, Galla T, Papalopulu N (2014). microRNA input into a neural ultradian oscillator controls emergence and timing of alternative cell states. Nat Commun, 5 Abstract.  Author URL.  Full text.

2013

Rummel C, Goodfellow M, Gast H, Hauf M, Amor F, Stibal A, Mariani L, Wiest R, Schindler K (2013). A systems-level approach to human epileptic seizures. Neuroinformatics, 11(2), 159-173. Abstract.  Author URL.
Wang Y, Goodfellow M, Taylor PN, Garry DJ, Baier G (2013). Computational modelling of microseizures and focal seizure onset. In  (Ed) Recent Advance in Predicting and Preventing Epileptic Sezures, 83-98.  Abstract.
Goodfellow M, Glendinning P (2013). Mechanisms of intermittent state transitions in a coupled heterogeneous oscillator model of epilepsy. J Math Neurosci, 3(1). Abstract.  Author URL.  Full text.
Taylor PN, Goodfellow M, Wang Y, Baier G (2013). Towards a large-scale model of patient-specific epileptic spike-wave discharges. Biol Cybern, 107(1), 83-94. Abstract.  Author URL.

2012

Al-Nuaimi Y, Goodfellow M, Paus R, Baier G (2012). A prototypic mathematical model of the human hair cycle. J Theor Biol, 310, 143-159. Abstract.  Author URL.
Goodfellow M, Taylor PN, Wang Y, Garry DJ, Baier G (2012). Modelling the role of tissue heterogeneity in epileptic rhythms. Eur J Neurosci, 36(2), 2178-2187. Abstract.  Author URL.
Schindler K, Gast H, Goodfellow M, Rummel C (2012). On seeing the trees and the forest: single-signal and multisignal analysis of periictal intracranial EEG. Epilepsia, 53(9), 1658-1668. Abstract.  Author URL.
Wang Y, Goodfellow M, Taylor PN, Baier G (2012). Phase space approach for modeling of epileptic dynamics. Phys Rev E Stat Nonlin Soft Matter Phys, 85(6 Pt 1). Abstract.  Author URL.
Baier G, Goodfellow M, Taylor PN, Wang Y, Garry DJ (2012). SPATIO-TEMPORAL MODELS TO PREDICT AND CONTROL EPILEPTIC SEIZURE DYNAMICS.  Author URL.
Goodfellow M, Schindler K, Baier G (2012). Self-organised transients in a neural mass model of epileptogenic tissue dynamics. Neuroimage, 59(3), 2644-2660. Abstract.  Author URL.
Baier G, Goodfellow M, Taylor PN, Wang Y, Garry DJ (2012). The importance of modeling epileptic seizure dynamics as spatio-temporal patterns. Front Physiol, 3 Abstract.  Author URL.  Full text.

2011

Goodfellow M, Schindler K, Baier G (2011). Intermittent spike-wave dynamics in a heterogeneous, spatially extended neural mass model. Neuroimage, 55(3), 920-932. Abstract.  Author URL.
Baier G, Goodfellow M, Taylor P, Wang Y (2011). SPONTANEOUS SPIKE-WAVE DISCHARGES IN SPATIALLY EXTENDED MODELS OF EPILEPTIC DYNAMICS.  Author URL.

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