Profile
Prof Nick Stone
Professor of Biomedical Imaging and Biosensing
(Streatham) 6531
01392 726531
Overview
Professor Nicholas Stone (h index = 52), Professor of Biomedical Imaging and Biosensing, School of Physics and Astronomy, University of Exeter is also an HCPC registered [CS3557] Consultant Clinical Scientist (Medical Physics), holding positions in two leading NHS Foundation Hospital Trusts. He recently led the School of Physics and Astronomy at the University of Exeter 2015-2018. Prior to that he was Director of Research.
Nick is the University Lead for Healthcare Technologies' and has a strong track record working at the interface between physics, engineering and medicine. In 2012 he was appointed to the position of Professor of Biomedical Imaging and Biosensing at the University of Exeter, leading him to relinquish the positions of Consultant Clinical Scientist and Head of the Biophotonics Research Unit at Gloucestershire Hospitals and Professor of Biophotonics at Cranfield University. There he established an internationally recognised research unit within a district general hospital pioneering novel optical techniques for diagnostics and therapeutics. He built this unit from scratch and succeeded in funding it in its entirety for 13-14 years.
He has International recognition as a leader in the field of biomedical vibrational spectroscopy for diagnostics. He was awarded Institute of Physics and Engineering in Medicine Acaxdemic Gold Medal (2020) and the Chief Scientific Officer’s National R&D Award for 2009, the ICORS - International Raman award in 2014 and various other national and international prizes. He have published 7 book chapters; over 200 peer reviewed papers and proceedings and 7 patents. He has been an invited speaker at over 60 national and international conferences and chaired and organised leading events in the field (SPEC 2008, 2010, 2012; FACSS Bioanalytical Section; Numerous IPEM Medical Physics Conferences; BMLA National and European Conferences; SPIE Conferences; Rank Prize).
Prof Stone has raised over £20 million grant income and led numerous projects to explore novel diagnostics and therapeutics utilising the power of light. He currently holds grants from the EPSRC, NIHR, MRC and CRUK of around £11.5M, covering fundamental science to clinical translation, with most being large scale multi-institutional and cross-disciplinary. NS’ current EPSRC grants exceed £8M as PI [EP/R020965/1 & EP/P012442/1] and Co-I [EP/S009957/1 & NS/A000063/1] and he is a holder of one of only a handful of EPSRC Health Technologies (HT) Programme and Strategic Equipment grants.
Prof Stone has worked in a national leadership role in Medical Physics (Director of Science, Institute of Physics and Engineering in Medicine (2009-2011); Vice President and Chair of Academic Advisory Group to Council (2011-2014)) and has sat on the board of various societies: the Institute of Physics in Medicine and Biology, British Medical Laser Association, the Head and Neck Optical Diagnostics Society. Recently as a Founder Director I helped to form the International Society of Clinical Spectroscopy (CLIRSPEC). He holds fellowships (FRSC, FIPEM, FSAS) from 3 international learned societies.
Publications
Copyright Notice: Any articles made available for download are for personal use only. Any other use requires prior permission of the author and the copyright holder.
| 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1996 | 1993 |
2024
- He S, Demir B, Bouzy P, Stone N, Ward C, Hamerton I. (2024) Taking a Tailored Approach to Material Design: A Mechanistic Study of the Selective Localization of Phase-Separated Graphene Microdomains, ACS Applied Materials and Interfaces, volume 16, no. 21, pages 27694-27704, DOI:10.1021/acsami.4c05666.
- Lyburn ID, Scott R, Cornford E, Bouzy P, Stone N, Greenwood C, Bouybayoune I, Pinder SE, Rogers K. (2024) Translating microcalcification biomarker information into the laboratory: A preliminary assessment utilizing core biopsies obtained from sites of mammographic calcification, Heliyon, volume 10, no. 6, DOI:10.1016/j.heliyon.2024.e27686.
- Gardner B, Haskell J, Matousek P, Stone N. (2024) Guided principal component analysis (GPCA): a simple method for improving detection of a known analyte, The Analyst, volume 149, no. 1, pages 205-211, DOI:10.1039/d3an00820g. [PDF]
2023
- Nallala J, Calabrese D, Gosling S, Lips E, Factor R, Hall A, Pinder S, Bouybayoune I, Sawyer E, King L. (2023) Molecular imaging of calcification and soft tissue defines prognosis of DCIS to invasive breast cancer, CANCER RESEARCH, volume 83, no. 7, DOI:10.1158/1538-7445.AM2023-5561. [PDF]
- Haskell J, Hubbard T, Murray C, Gardner B, Ives C, Ferguson D, Stone N. (2023) High wavenumber Raman spectroscopy for intraoperative assessment of breast tumour margins, Analyst, volume 148, no. 18, pages 4373-4385, DOI:10.1039/d3an00574g. [PDF]
- Gosling SB, Arnold EL, Davies SK, Cross H, Bouybayoune I, Calabrese D, Nallala J, Pinder SE, Fu L, Lips EH. (2023) Microcalcification crystallography as a potential marker of DCIS recurrence, Sci Rep, volume 13, no. 1, DOI:10.1038/s41598-023-33547-8. [PDF]
- Haskell J, Hubbard T, Murray C, Ives C, Olsen S, Tillett R, Knight H, Ferguson D, Stone N. (2023) A probe delivering high wavenumber Raman spectroscopy diagnostics for intraoperative margin analysis, European Journal of Surgical Oncology, volume 49, no. 5, pages e263-e264, DOI:10.1016/j.ejso.2023.03.179.
- Mosca S, Sowoidnich K, Mehta M, Skinner WH, Gardner B, Palombo F, Stone N, Matousek P. (2023) 10 kHz Shifted-Excitation Raman Difference Spectroscopy with Charge-Shifting Charge-Coupled Device Read-Out for Effective Mitigation of Dynamic Interfering Backgrounds, Applied Spectroscopy, volume 77, no. 6, pages 569-582, DOI:10.1177/00037028231167441. [PDF]
- Nallala J, Calabrese D, Gosling S, Lips E, Factor R, Hall A, Pinder SE, Bouybayoune I, King L, Marks J. (2023) Abstract P4-02-22: Breast microcalcification chemistry predicts DCIS prognosis, Cancer Research, volume 83, no. 5_Supplement, DOI:10.1158/1538-7445.sabcs22-p4-02-22.
- Bouzy P, Lyburn ID, Pinder SE, Scott R, Mansfield J, Moger J, Greenwood C, Bouybayoune I, Cornford E, Rogers K. (2023) Exploration of utility of combined optical photothermal infrared and Raman imaging for investigating the chemical composition of microcalcifications in breast cancer, Anal Methods, volume 15, no. 13, pages 1620-1630, DOI:10.1039/d2ay01197b. [PDF]
2022
- Ireland P, Old O, Hornby S, Kendall C, Barr H, Shore A, Stone N. (2022) Raman Needle Probe Lymph Node Assessment for Oesophageal Cancer: The DOLOMITE Study, BRITISH JOURNAL OF SURGERY, volume 109, DOI:10.1093/bjs/znac404.191. [PDF]
- Scott R, Lyburn I, Cornford E, Bouzy P, Stone N, Greenwood C, Bouybayoune I, Pinder S, Rogers K. (2022) Breast calcification micromorphology classification, British Journal of Radiology, volume 95, no. 1139, DOI:10.1259/bjr.20220485.
- Bench C, Nallala J, Wang C-C, Sheridan H, Stone N. (2022) Unsupervised segmentation of biomedical hyperspectral image data: tackling high dimensionality with convolutional autoencoders, Biomedical Optics Express, volume 13, no. 12, pages 6373-6373, DOI:10.1364/boe.476233. [PDF]
- Bench C, Nallala J, Wang C-C, Sheridan H, Stone N. (2022) Unsupervised segmentation of biomedical hyperspectral image data: tackling high dimensionality with convolutional autoencoders. [PDF]
- Mosca S, Gardner B, Salimi M, Palombo F, Stone N, Matousek P. (2022) Spatially Offset Raman Spectroscopy for estimating the depth of inclusion in diffusely scattering samples, Optics InfoBase Conference Papers.
- He S, Bouzy P, Stone N, Ward C, Hamerton I. (2022) Analysis of the Chemical Distribution of Self-Assembled Microdomains with the Selective Localization of Amine-Functionalized Graphene Nanoplatelets by Optical Photothermal Infrared Microspectroscopy, Analytical Chemistry, volume 94, no. 34, pages 11848-11855, DOI:10.1021/acs.analchem.2c02306. [PDF]
- Wang C-C, Mansfield JC, Stone N, Moger J. (2022) Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy, J Vis Exp, no. 183, DOI:10.3791/63637. [PDF]
- Nallala J, Griggs R, Lloyd GR, Stone N, Shepherd NA. (2022) Infrared Spectroscopic Analysis in the Differentiation of Epithelial Misplacement From Adenocarcinoma in Sigmoid Colonic Adenomatous Polyps, Clinical Pathology, volume 15, pages 2632010X2210889-2632010X2210889, DOI:10.1177/2632010x221088960. [PDF]
- Mohamed MSN, Almond M, Kendall C, Dudgeon A, Mansfield J, Stone N, Barr H. (2022) 417Vibrational Spectroscopy: A Rapid Tool for Soft Tissue Sarcoma Assessment, BRITISH JOURNAL OF SURGERY, volume 109, DOI:10.1093/bjs/znac039.283. [PDF]
- Nallala J, Calabrese D, Gosling S, Hall A, Pinder S, Bouybayoune I, King L, Marks J, Lips E, Lynch T. (2022) Abstract P2-08-07: Predicting DCIS prognosis using infrared and raman spectroscopy of breast calcifications and soft-tissue microstructure, Cancer Research, volume 82, no. 4_Supplement, DOI:10.1158/1538-7445.sabcs21-p2-08-07.
- Gosling S, Calabrese D, Nallala J, Greenwood C, Pinder S, King L, Marks J, Pinto D, Lynch T, Lyburn ID. (2022) A multi-modal exploration of heterogeneous physico-chemical properties of DCIS breast microcalcifications, ANALYST, volume 147, no. 8, pages 1641-1654, DOI:10.1039/d1an01548f. [PDF]
- Dey P, Vaideanu A, Mosca S, Salimi M, Gardner B, Palombo F, Uchegbu I, Baumberg J, Schatzlein A, Matousek P. (2022) Surface enhanced deep Raman detection of cancer tumour through 71 mm of heterogeneous tissue, Nanotheranostics, volume 6, no. 3, pages 337-349, DOI:10.7150/ntno.71510. [PDF]
- Salimi M, Mosca S, Gardner B, Palombo F, Matousek P, Stone N. (2022) Nanoparticle-Mediated Photothermal Therapy Limitation in Clinical Applications Regarding Pain Management, Nanomaterials, volume 12, no. 6, pages 922-922, DOI:10.3390/nano12060922. [PDF]
2021
- Bouzy P, O'Grady S, Madupalli H, Tecklenburg M, Rogers K, Palombo F, Morgan MP, Stone N. (2021) A time-course Raman spectroscopic analysis of spontaneous in vitro microcalcifications in a breast cancer cell line, Lab Invest, volume 101, no. 9, pages 1267-1280, DOI:10.1038/s41374-021-00619-0. [PDF]
- Hubbard T, Dudgeon A, Ferguson D, Shore A, Stone N. (2021) P100. High wavenumber Raman spectroscopy tissue differentiation for intraoperative margin analysis, European Journal of Surgical Oncology, volume 47, no. 5, DOI:10.1016/j.ejso.2021.03.104.
- Moran L, Wordingham F, Gardner B, Stone N, Harries T. (2021) An experimental and numerical modelling investigation of the optical properties of Intralipid using deep Raman spectroscopy, Analyst, DOI:10.1039/D1AN01801A.
- Kansiz M, Spadea A, Nallala J, Lima C, Muhamadali H, Denbigh J, Lawrence J, Bakir G, Gardner P, Stone N. (2021) Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy, Advanced Chemical Microscopy for Life Science and Translational Medicine 2021, DOI:10.1117/12.2578662.
- Morrish R, Yim KHW, Pagliara S, Palombo F, Chahwan R, Stone N. (2021) Single cell label-free probing of chromatin dynamics during B lymphocyte maturation, DOI:10.1101/2021.01.12.426344.
- Bouzy P, O'Grady S, Madupalli H, Tecklenburg M, Rogers K, Palombo F, Morgan MP, Stone N. (2021) A time-course Raman spectroscopic analysis of spontaneous in vitro microcalcifications in a breast cancer cell line, LABORATORY INVESTIGATION, volume 101, no. 9, pages 1267-1280, DOI:10.1038/s41374-021-00619-0. [PDF]
- Morrish R. (2021) Monitoring chromatin remodelling in xed and live immune cells using vibrational spectroscopy and micro uidics.
- Gosling S, Calabrese D, Arnold E, Nallala J, Greenwood C, Stone N, Rogers K. (2021) Breast calcification chemistry as a biomarker for progression of in-situ breast cancer, Bone Reports, volume 14, pages 100787-100787, article no. 100787, DOI:10.1016/j.bonr.2021.100787. [PDF]
- Mosca S, Conti C, Stone N, Matousek P. (2021) Spatially offset Raman spectroscopy, Nature Reviews Methods Primers, volume 1, no. 1, article no. 21, DOI:10.1038/s43586-021-00019-0. [PDF]
- Mosca S, Dey P, Salimi M, Gardner B, Palombo F, Stone N, Matousek P. (2021) Estimating the Reduced Scattering Coefficient of Turbid Media Using Spatially Offset Raman Spectroscopy, Anal Chem, volume 93, no. 7, pages 3386-3392, DOI:10.1021/acs.analchem.0c04290. [PDF]
- Morrish R, Yim KHW, Pagliara S, Palombo F, Chahwan R, Stone N. (2021) Data supporting Morrish et al. (2021) Frontiers in Cell and Developmental Biology.
- Hubbard T. (2021) Using Raman Spectroscopy for Intraoperative Margin Analysis in Breast Conserving Surgery.
- Hubbard TJE, Dudgeon AP, Ferguson DJ, Shore AC, Stone N. (2021) Utilization of Raman spectroscopy to identify breast cancer from the water content in surgical samples containing blue dye, Translational Biophotonics, volume 3, no. 2, DOI:10.1002/tbio.202000023. [PDF]
- Gardner B, Matousek P, Stone N. (2021) Self-absorption corrected non-invasive transmission Raman spectroscopy (of biological tissue), The Analyst, volume 146, no. 4, pages 1260-1267, DOI:10.1039/d0an01940b. [PDF]
- Nicolson F, Kircher MF, Stone N, Matousek P. (2021) Spatially offset Raman spectroscopy for biomedical applications, Chemical Society Reviews, volume 50, no. 1, pages 556-568, DOI:10.1039/d0cs00855a. [PDF]
2020
- Hubbard T, Ferguson D, Shore A, Stone N. (2020) P122: Raman spectroscopy for intraoperative margin analysis in breast conserving surgery, European Journal of Surgical Oncology, volume 46, no. 6, DOI:10.1016/j.ejso.2020.03.161.
- Gardner B, Haskell J, Ghita A, Matousek P, Ives C, Ferguson D, Stone N. (2020) P123: Preliminary evaluation of raman spectroscopy to detect calcifications in excised breast tissue: A prelude to the first in vivo whole breast study, European Journal of Surgical Oncology, volume 46, no. 6, pages e43-e44, DOI:10.1016/j.ejso.2020.03.162.
- Bailey M, Gardner B, Alunni-Cardinali M, Caponi S, Fioretto D, Stone N, Palombo F. (2020) Monitoring the refractive index of tissue models using light scattering spectroscopy, DOI:10.48550/arxiv.2009.02274.
- Bailey M, Gardner B, Alunni-Cardinali M, Caponi S, Fioretto D, Stone N, Palombo F. (2020) Monitoring the refractive index of tissue models using light scattering spectroscopy, Appl. Spectrosc, volume 75, pages 574-580. [PDF]
- Guo S, Beleites C, Neugebauer U, Abalde-Cela S, Afseth NK, Alsamad F, Anand S, Araujo-Andrade C, Aškrabić S, Avci E. (2020) Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study, Anal Chem, volume 92, no. 24, pages 15745-15756, DOI:10.1021/acs.analchem.0c02696. [PDF]
- Bouzy P. (2020) Novel infrared and Raman spectroscopic imaging for the elucidation of specific changes in breast microcalcifications.
- Martínez Pancorbo P. (2020) Development and Evaluation of Multifunctional Colloidal Composite Nanoparticles for Potential Combined Cancer Cell Diagnosis and Therapy.
- Mosca S, Dey P, Salimi M, Palombo F, Stone N, Matousek P. (2020) Non-invasive depth determination of inclusion in biological tissues using spatially offset Raman spectroscopy with external calibration, The Analyst, volume 145, no. 23, pages 7623-7629, DOI:10.1039/d0an01292k. [PDF]
- Dey P, Blakey I, Stone N. (2020) Diagnostic prospects and preclinical development of optical technologies using gold nanostructure contrast agents to boost endogenous tissue contrast, Chemical Science, volume 11, no. 33, pages 8671-8685, DOI:10.1039/d0sc01926g. [PDF]
- Ghita A, Hubbard T, Matousek P, Stone N. (2020) Noninvasive Detection of Differential Water Content Inside Biological Samples Using Deep Raman Spectroscopy, Analytical Chemistry, volume 92, no. 14, pages 9449-9453, DOI:10.1021/acs.analchem.0c01842. [PDF]
- Tabish TA, Dey P, Mosca S, Salimi M, Palombo F, Matousek P, Stone N. (2020) Smart Gold Nanostructures for Light Mediated Cancer Theranostics: Combining Optical Diagnostics with Photothermal Therapy, Advanced Science, volume 7, no. 15, DOI:10.1002/advs.201903441. [PDF]
- Liberda D, Hermes M, Koziol P, Stone N, Wrobel TP. (2020) Translation of an esophagus histopathological FT-IR imaging model to a fast quantum cascade laser modality, Journal of Biophotonics, volume 13, no. 8, DOI:10.1002/jbio.202000122.
- Seddon AB, Napier B, Lindsay I, Lamrini S, Moselund PM, Stone N, Bang O, Farries M. (2020) Erratum: Prospective on using fibre mid-infrared supercontinuum laser sources for: In vivo spectral discrimination of disease (Analyst (2018) 143 (5874-5887) DOI: 10.1039/c8an01396a), Analyst, volume 145, no. 10, pages 3757-3758, DOI:10.1039/c9an90110h.
- Frost J. (2020) VIBRATIONAL SPECTROSCOPY FOR THE ASSESSMENT OF VULVAL DISEASE.
- Gardner B, Stone N, Matousek P. (2020) Noninvasive simultaneous monitoring of pH and depth using surface-enhanced deep Raman spectroscopy, Journal of Raman Spectroscopy, volume 51, no. 7, pages 1078-1082, DOI:10.1002/jrs.5875.
- Nallala J, Jeynes C, Saunders S, Smart N, Lloyd G, Riley L, Salmon D, Stone N. (2020) Characterization of colorectal mucus using infrared spectroscopy: a potential target for bowel cancer screening and diagnosis, Laboratory Investigation, volume 100, no. 8, pages 1102-1110, DOI:10.1038/s41374-020-0418-3. [PDF]
- Mosca S, Lanka P, Stone N, Konugolu Venkata Sekar S, Matousek P, Valentini G, Pifferi A. (2020) Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy, Biomedical Optics Express, volume 11, no. 3, pages 1697-1697, DOI:10.1364/boe.386349. [PDF]
- Bailey M, Correa N, Harding S, Stone N, Brasselet S, Palombo F. (2020) Brillouin microspectroscopy data of tissue-mimicking gelatin hydrogels, Data in Brief, volume 29, pages 105267-105267, article no. 105267, DOI:10.1016/j.dib.2020.105267. [PDF]
- Dey P, Tabish TA, Mosca S, Palombo F, Matousek P, Stone N. (2020) Plasmonic Nanoassemblies: Tentacles Beat Satellites for Boosting Broadband NIR Plasmon Coupling Providing a Novel Candidate for SERS and Photothermal Therapy, Small, volume 16, no. 10, DOI:10.1002/smll.201906780. [PDF]
- Bailey M, Correa N, Harding S, Stone N, Brasselet S, Palombo F. (2020) Data supporting Bailey et al. (2020) Data in Brief.
2019
- Bailey M, Alunni-Cardinali M, Correa N, Caponi S, Holsgrove T, Barr H, Stone N, Winlove CP, Fioretto D, Palombo F. (2019) Brillouin-derived viscoelastic parameters of hydrogel tissue models, DOI:10.48550/arxiv.1912.08292.
- Bailey M, Alunni-Cardinali M, Correa N, Caponi S, Holsgrove T, Barr H, Stone N, Winlove CP, Fioretto D, Palombo F. (2019) Brillouin-derived viscoelastic parameters of hydrogel tissue models, Sci. Adv. 6 (2020) eabc1937. [PDF]
- Gosling S, Scott R, Greenwood C, Bouzy P, Nallala J, Lyburn I, Stone N, Rogers K. (2019) Breast Microcalcifications - Novel Biomarkers for Breast Tissue Pathology, BREAST CANCER RESEARCH, volume 21. [PDF]
- Rogers K, Lyburn I, Gosling S, Stone N, Krupakar N. (2019) Breast Cancer: Early diagnosis using materials immortalisation, BREAST CANCER RESEARCH, volume 21. [PDF]
- Stone N. (2019) Calcification Microstructure Reflects Breast Tissue Microenvironment, Journal of Mammary Gland Biology and Neoplasia, DOI:10.1007/s10911-019-09441-3.
- Hubbard TJE, Shore A, Stone N. (2019) Raman spectroscopy for rapid intra-operative margin analysis of surgically excised tumour specimens, Analyst, volume 144, no. 22, pages 6479-6496, DOI:10.1039/c9an01163c. [PDF]
- Alghamdi S. (2019) Shedding New Light on Cancer with Non-Linear Optical Microscopy.
- Gardner B, Matousek P, Stone N. (2019) Subsurface Chemically Specific Measurement of pH Levels in Biological Tissues Using Combined Surface-Enhanced and Deep Raman, Anal Chem, volume 91, no. 17, pages 10984-10987, DOI:10.1021/acs.analchem.9b01015. [PDF]
- Martinez Pancorbo P, Thummavichai K, Clark L, Tabish TA, Mansfield J, Gardner B, Chang H, Stone N, Zhu Y. (2019) Novel Au–SiO2–WO3 Core–Shell Composite Nanoparticles for Surface-Enhanced Raman Spectroscopy with Potential Application in Cancer Cell Imaging, Adv. Funct. Mater, volume 29, no. 46, DOI:10.1002/adfm.201903549. [PDF]
- Bouzy P, O'Grady S, Palombo F, Morgan MP, Stone N. (2019) Exploring the relationship between an in vitro model of breast cancer cell mineralisation and the cancer grade specific composition of ex vivo microcalcifications, CANCER RESEARCH, volume 79, no. 4, DOI:10.1158/1538-7445.SABCS18-P6-01-03. [PDF]
- Stone N. (2019) Video-rate, mid-infrared hyperspectral upconversion imaging, Optica, DOI:10.1364/OPTICA.6.000702.
- Brandstrup Morrish R, Hermes M, Metz J, Stone N, Pagliara S, Chahwan R, Palombo F. (2019) Single cell imaging of nuclear architecture changes, Frontiers in Immunology, volume 7, pages 1-14, article no. 141, DOI:10.3389/fcell.2019.00141.
- Mosca S, Dey P, Tabish TA, Palombo F, Stone N, Matousek P. (2019) Spatially Offset and Transmission Raman Spectroscopy for Determination of Depth of Inclusion in Turbid Matrix, Anal Chem, volume 91, no. 14, pages 8994-9000, DOI:10.1021/acs.analchem.9b01222. [PDF]
- Gardner B, Matousek P, Stone N. (2019) Direct monitoring of light mediated hyperthermia induced within mammalian tissues using surface enhanced spatially offset Raman spectroscopy (T-SESORS), Analyst, volume 144, no. 11, pages 3552-3555, DOI:10.1039/c8an02466a. [PDF]
- Chudasama D, Katopodis P, Stone N, Haskell J, Sheridan H, Gardner B, Urnovitz H, Schuetz E, Beck J, Hall M. (2019) Liquid Biopsies in Lung Cancer: Four Emerging Technologies and Potential Clinical Applications, Cancers (Basel), volume 11, no. 3, DOI:10.3390/cancers11030331. [PDF]
2018
- Hall M, Chudasama D, Roberts C, Stone N, Vardaki M, Urnowitz H, Schuetz E, Beck J, Karteris E. (2018) Applications of liquid biopsies as prognostic markers in patients (pts) with advanced ovarian cancer (AOC) on metronomic cyclophosphamide (MCy) with or without nintedanib (N) (Trans METRO-BIBF), Journal of Clinical Oncology, volume 36, no. 15_suppl, pages e24065-e24065, DOI:10.1200/jco.2018.36.15_suppl.e24065.
- Paniagua-Diaz AM, Ghita A, Vettenburg T, Stone N, Bertolotti J. (2018) Enhanced deep detection of Raman scattered light by wavefront shaping, DOI:10.48550/arxiv.1807.10682.
- Hermes M. (2018) Rapid high-resolution mid-IR imaging for molecular spectral histopathological diagnosis of oesophageal cancers.
- Greenwood C, Clement J, Dicken A, Evans P, Lyburn I, Martin R, Stone N, Zioupos P, Rogers K. (2018) POINT-OF-CARE HIGH ACCURACY FRACTURE RISK PREDICATION FOR OSTEOPOROSIS, OSTEOPOROSIS INTERNATIONAL, volume 29, pages 638-639. [PDF]
- Seddon AB, Napier B, Lindsay I, Lamrini S, Moselund PM, Stone N, Bang O, Farries M. (2018) Prospective on using fibre mid-infrared supercontinuum laser sources for in vivo spectral discrimination of disease, Analyst, volume 143, no. 24, pages 5874-5887, DOI:10.1039/c8an01396a. [PDF]
- Tseng YP, Bouzy P, Pedersen C, Stone N, Tidemand-Lichtenberg P. (2018) Upconversion raster scanning microscope for long-wavelength infrared imaging of breast cancer microcalcifications, Biomedical Optics Express, volume 9, no. 10, pages 4979-4987, DOI:10.1364/BOE.9.004979.
- Pahlow S, Weber K, Popp J, Wood BR, Kochan K, Rüther A, Perez-Guaita D, Heraud P, Stone N, Dudgeon A. (2018) Application of Vibrational Spectroscopy and Imaging to Point-of-Care Medicine: A Review, Appl Spectrosc, volume 72, no. 1_suppl, pages 52-84, DOI:10.1177/0003702818791939. [PDF]
- Paniagua-Diaz AM, Ghita A, Vettenburg T, Stone N, Bertolotti J. (2018) Enhanced deep detection of Raman scattered light by wavefront shaping, Optics Express, volume 26, no. 26, pages 33565-33574, DOI:10.1364/OE.26.033565.
- Peñaranda F, Naranjo V, Lloyd GR, Kastl L, Kemper B, Schnekenburger J, Nallala J, Stone N. (2018) Discrimination of skin cancer cells using Fourier transform infrared spectroscopy, Comput Biol Med, volume 100, pages 50-61, DOI:10.1016/j.compbiomed.2018.06.023. [PDF]
- Ghita A, Matousek P, Stone N. (2018) Sensitivity of Transmission Raman Spectroscopy Signals to Temperature of Biological Tissues, Scientific Reports, volume 8, no. 1, DOI:10.1038/s41598-018-25465-x.
- Scotté C, de Aguiar HB, Marguet D, Green EM, Bouzy P, Vergnole S, Winlove CP, Stone N, Rigneault H. (2018) Assessment of Compressive Raman versus Hyperspectral Raman for Microcalcification Chemical Imaging, Anal Chem, volume 90, no. 12, pages 7197-7203, DOI:10.1021/acs.analchem.7b05303. [PDF]
- Bouzy P, Tseng YP, Pedersen C, Tidemand-Lichtenberg P, Palombo F, Stone N. (2018) Advances in mid-infrared spectroscopic imaging for analysis of breast cancer associated microcalcifications, Optics InfoBase Conference Papers, volume Part F87-MICS 2018, DOI:10.1364/MICS.2018.MT3C.8.
- Baker MJ, Byrne HJ, Chalmers J, Gardner P, Goodacre R, Henderson A, Kazarian SG, Martin FL, Moger J, Stone N. (2018) Correction: Clinical applications of infrared and Raman spectroscopy: state of play and future challenges, The Analyst, volume 143, no. 8, pages 1934-1934, DOI:10.1039/c8an90029a. [PDF]
- Baker MJ, Byrne H, Chalmers JM, Gardner P, Goodacre R, Henderson A, Kazarian S, Martin FL, Moger J, Stone N. (2018) Clinical Applications of Infrared and Raman Spectroscopy: State of Play and Future Challenges, Analyst.
- Petersen CR, Prtljaga N, Farries M, Ward J, Napier B, Lloyd GR, Nallala J, Stone N, Bang O. (2018) Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber, Optical Biopsy XVI: Toward Real-Time Spectroscopic Imaging and Diagnosis, volume 10489.
- Ghita A, Matousek P, Stone N. (2018) Characterisation of a novel transmission Raman spectroscopy platform for non-invasive detection of breast micro-calcifications, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry, volume 10490.
- Tseng YP, Bouzy P, Stone N, Pedersen C, Tidemand-Lichtenberg P. (2018) Long wavelength identification of microcalcifications in breast cancer tissue using a quantum cascade laser and upconversion detection, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry, volume 10490.
- Hermes M, Morrish RB, Huot L, Meng L, Junaid S, Tomko J, Lloyd GR, Masselink WT, Tidemand-Lichtenberg P, Pedersen C. (2018) Mid-IR hyperspectral imaging for label-free histopathology and cytology, Journal of Optics, volume 20, no. 2, pages 023002-023002.
- Stone N, Petersen CR. (2018) Mid-infrared multispectral tissue imaging using a chalcogenide fiber supercontinuum source, Optics Letters, DOI:10.1364/OL.43.000999.
- Palombo F, Tamagnini F, Jeynes JCG, Mattana S, Swift I, Nallala J, Hancock J, Brown JT, Randall AD, Stone N. (2018) Detection of Aβ plaque-associated astrogliosis in Alzheimer’s disease brain by spectroscopic imaging and immunohistochemistry, Analyst, volume 143, pages 850-857, article no. 4, DOI:10.1039/c7an01747b.
- Lewis AT, Gaifulina R, Guppy NJ, Isabelle M, Dorney J, Lloyd GR, Rodriguez-Justo M, Kendall C, Stone N, Thomas GM. (2018) Developing Raman spectroscopy as a diagnostic tool for label-free antigen detection, J Biophotonics, volume 11, no. 2, DOI:10.1002/jbio.201700028. [PDF]
- Ghita A, Matousek P, Stone N. (2018) High sensitivity non-invasive detection of calcifications deep inside biological tissue using Transmission Raman Spectroscopy, J Biophotonics, volume 11, no. 1, DOI:10.1002/jbio.201600260. [PDF]
- Old O, Lloyd G, Isabelle M, Almond LM, Kendall C, Baxter K, Shepherd N, Shore A, Stone N, Barr H. (2018) Automated cytological detection of Barrett's neoplasia with infrared spectroscopy, J Gastroenterol, volume 53, no. 2, pages 227-235, DOI:10.1007/s00535-017-1344-z. [PDF]
2017
- Baumberg J, Bell S, Bonifacio A, Chikkaraddy R, Chisanga M, Corsetti S, Delfino I, Eremina O, Fasolato C, Faulds K. (2017) SERS in biology/biomedical SERS: General discussion, Faraday Discussions, volume 205, pages 429-456, DOI:10.1039/c7fd90089a.
- Hutchings J, Day JCC, Stone N. (2017) Optical device.
- Bouzy P, Palombo F, Stone N. (2017) spectroscopic tools for the elucidation of disease specific changes in breast cancer, Optics InfoBase Conference Papers, volume Part F81-EQEC 2017.
- Hermes M, Nallala J, Huot L, Tomko J, Junaid S, Tidemand-Lichtenberg P, Pedersen C, Stone N. (2017) Towards rapid high-resolution mid-ir imaging for molecular spectral histopathological diagnosis of oesophageal cancers, Optics InfoBase Conference Papers, volume Part F81-EQEC 2017.
- Kastl L, Kemper B, Lloyd GR, Nallala J, Stone N, Naranjo V, Penaranda F, Schnekenburger J. (2017) Mid-infrared spectroscopy in skin cancer cell type identification, Optics InfoBase Conference Papers, volume Part F61-ECBO 2017, DOI:10.1117/12.2287263.
- Gardner B, Stone N, Matousek P. (2017) Noninvasive Determination of Depth in Transmission Raman Spectroscopy in Turbid Media Based on Sample Differential Transmittance, Anal Chem, volume 89, no. 18, pages 9730-9733, DOI:10.1021/acs.analchem.7b01469. [PDF]
- Vardaki MZ, Sheridan H, Stone N, Matousek P. (2017) Determination of Depth in Transmission Raman Spectroscopy in Turbid Media Using a Beam Enhancing Element, Applied Spectroscopy, volume 71, no. 8, pages 1849-1855, DOI:10.1177/0003702817691540.
- Peñaranda F, Naranjo V, Verdú-Monedero R, Lloyd GR, Nallala J, Stone N. (2017) Multimodal registration of optical microscopic and infrared spectroscopic images from different tissue sections: An application to colon cancer, Digital Signal Processing: A Review Journal, volume 68, pages 1-15, DOI:10.1016/j.dsp.2017.04.014.
- Kastl L, Kemper B, Lloyd GR, Nallala J, Stone N, Naranjo V, Penaranda F, Schnekenburger J. (2017) Performance of mid infrared spectroscopy in skin cancer cell type identification, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 10060, DOI:10.1117/12.2253314.
- Old OJ, Lloyd GR, Nallala J, Isabelle M, Almond LM, Shepherd NA, Kendall CA, Shore AC, Barr H, Stone N. (2017) Rapid infrared mapping for highly accurate automated histology in Barrett's oesophagus, ANALYST, volume 142, no. 8, pages 1227-1234, DOI:10.1039/c6an01871h. [PDF]
- Scott R, Kendall C, Stone N, Rogers K. (2017) Elemental vs. phase composition of breast calcifications, Sci Rep, volume 7, no. 1, DOI:10.1038/s41598-017-00183-y. [PDF]
- Frost J, Ludeman L, Hillaby K, Gornall R, Lloyd G, Kendall C, Shore AC, Stone N. (2017) Raman spectroscopy and multivariate analysis for the non invasive diagnosis of clinically inconclusive vulval lichen sclerosus, Analyst, volume 142, no. 8, pages 1200-1206, DOI:10.1039/c6an02009g. [PDF]
- Old OJ, Lloyd GR, Nallala J, Isabelle M, Almond LM, Shepherd NA, Kendall CA, Shore AC, Barr H, Stone N. (2017) Rapid infrared mapping for highly accurate automated histology in Barrett's oesophagus, Analyst, volume 142, no. 8, pages 1227-1234, DOI:10.1039/c6an01871h. [PDF]
- Lewis AT, Gaifulina R, Isabelle M, Dorney J, Woods ML, Lloyd GR, Lau K, Rodriguez-Justo M, Kendall C, Stone N. (2017) Mirrored stainless steel substrate provides improved signal for Raman spectroscopy of tissue and cells, Journal of Raman Spectroscopy, volume 48, no. 1, pages 119-125, DOI:10.1002/jrs.4980.
2016
- Stone N, Nallala J, Lloyd GR. (2016) Identification of gastrointestinal cancers using rapid mid-IR spectral imaging, SPIE Newsroom, DOI:10.1117/2.1201605.006463.
- Barr H, Isabelle M, Old O, Lloyd G, Lau K, Dorney J, Lewis A, Geraint T, Shepherd N, Bell I. (2016) RAMAN SPECTROSCOPYCANCER DIAGNOSTIC FOR PATHOLOGY OF BARRETT'S OESOPHAGUS, GUT, volume 65, pages A177-A177, DOI:10.1136/gutjnl-2016-312388.324. [PDF]
- Frost J, Ludeman L, Hillaby K, Gornall R, Lloyd G, Kendall C, Shore AC, Stone N. (2016) Identification of cancer associated molecular changes in histologically benign vulval disease found in association with vulval squamous cell carcinoma using Fourier transform infrared spectroscopy, Analytical Methods, volume 8, no. 48, pages 8452-8460, DOI:10.1039/c6ay03059a.
- Peñaranda F, Naranjo V, Kastl L, Kemper B, Lloyd GR, Nallala J, Stone N, Schnekenburger J. (2016) Multivariate classification of Fourier transform infrared hyperspectral images of skin cancer cells, European Signal Processing Conference, volume 2016-November, pages 1328-1332, DOI:10.1109/EUSIPCO.2016.7760464.
- Old O, Lloyd G, Isabelle M, Kendall C, Shepherd N, Stone N, Shore A, Barr H. (2016) Detection of Barrett's Neoplasia In Oesophageal Cells Using Infrared Spectroscopy, BRITISH JOURNAL OF SURGERY, volume 103, pages 43-43. [PDF]
- Stone N, scott R, Rogers KD. (2016) Relationships between pathology and crystal structure in breast calcifications: an in situ X-ray diffraction study in histological sections, Nature Journal of Breast Cancer, volume 16029.
- Greenwood C, Clement J, Dicken A, Evans JPO, Lyburn I, Martin RM, Rogers K, Stone N, Zioupos P. (2016) Towards new material biomarkers for fracture risk, Bone, volume 93, pages 55-63, DOI:10.1016/j.bone.2016.09.006. [PDF]
- Ghita A, Matousek P, Stone N. (2016) Exploring the effect of laser excitation wavelength on signal recovery with deep tissue transmission Raman spectroscopy, Analyst, volume 141, no. 20, pages 5738-5746, DOI:10.1039/c6an00490c. [PDF]
- Kastl L, Kemper B, Lloyd GR, Nallala J, Stone N, Naranjo V, Penaranda F, Schnekenburger J. (2016) Potential of mid IR spectroscopy in the rapid label free identification of skin malignancies, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2208897. [PDF]
- Nallala J, Lloyd GR, Kendall C, Barr H, Shepherd N, Stone N. (2016) Identification of GI cancers utilising rapid mid-infrared spectral imaging, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2209363. [PDF]
- Penaranda F, Naranjo V, Verdu R, Lloyd GR, Nallala J, Stone N. (2016) A two-step framework for the registration of HE stained and FTIR images, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2208869. [PDF]
- Lindsay ID, Valle S, Ward J, Stevens G, Farries M, Huot L, Brooks C, Moselund PM, Vinella RM, Abdalla M. (2016) Towards supercontinuum-driven hyperspectral microscopy in the mid-infrared, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2210836. [PDF]
- Seddon AB, Benson TM, Sujecki S, Abdel-Moneim N, Tang Z, Furniss D, Sojka L, Stone N, Jayakrupakar N, Lloyd GR. (2016) Towards the mid-infrared optical biopsy, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2211584. [PDF]
- Lloyd GR, Nallala J, Stone N. (2016) Investigating the effect of pixel size on high spatial resolution FTIR imaging for detection of colorectal cancer, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2210844. [PDF]
- Horsnell JD, Kendall C, Stone N. (2016) Towards the intra-operative use of Raman spectroscopy in breast cancer—overcoming the effects of theatre lighting, Lasers in Medical Science, volume 31, no. 6, pages 1143-1149, DOI:10.1007/s10103-016-1959-y.
- Dicken AJ, Evans JPO, Rogers KD, Stone N, Greenwood C, Godber SX, Clement JG, Lyburn ID, Martin RM, Zioupos P. (2016) Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter, Scientific Reports, volume 6, DOI:10.1038/srep29011.
- Fullwood LM, Iping Petterson IE, Dudgeon AP, Lloyd GR, Kendall C, Hall C, Day JCC, Stone N. (2016) Evaluation of a multi-fibre needle Raman probe for tissue analysis, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 9704, DOI:10.1117/12.2230005.
- Lau K, Isabelle M, Lloyd GR, Old O, Shepherd N, Bell IM, Dorney J, Lewis A, Gaifulina R, Rodriguez-Justo M. (2016) The road map towards providing a robust Raman spectroscopy-based cancer diagnostic platform and integration into clinic, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 9704, DOI:10.1117/12.2230007.
- Sammon C, Schultz ZD, Kazarian S, Barr H, Goodacre R, Graham D, Baker MJ, Gardner P, Wood B, Campbell CJ. (2016) Spectral Pathology: general discussion, Faraday Discuss, volume 187, pages 155-186, DOI:10.1039/C6FD90011A. [PDF]
- Baker MJ, Goodacre R, Sammon C, Marques MP, Gardner P, Tipping W, Sulé-Suso J, Wood B, Byrne HJ, Hermes M. (2016) Single cell analysis/data handling: general discussion, Faraday Discuss, volume 187, pages 299-327, DOI:10.1039/C6FD90012G. [PDF]
- Goodacre R, Sergo V, Barr H, Sammon C, Schultz ZD, Baker MJ, Graham D, Marques MP, Sulé-Suso J, Livermore J. (2016) Clinical Spectroscopy: general discussion, Faraday Discuss, volume 187, pages 429-460, DOI:10.1039/C6FD90013E. [PDF]
- Goodacre R, Baker MJ, Graham D, Schultz ZD, Diem M, Marques MP, Cinque G, Vernooij R, Sulé-Suso J, Byrne HJ. (2016) Biofluids and other techniques: general discussion, Faraday Discuss, volume 187, pages 575-601, DOI:10.1039/C6FD90014C. [PDF]
- Vardaki MZ, Matousek P, Stone N. (2016) Characterisation of signal enhancements achieved when utilizing a photon diode in deep Raman spectroscopy of tissue, Biomedical Optics Express, volume 7, no. 6, pages 2130-2141, DOI:10.1364/BOE.7.002130.
- Matousek P, Stone N. (2016) Development of deep subsurface Raman spectroscopy for medical diagnosis and disease monitoring, Chemical Society Reviews, volume 45, no. 7, pages 1794-1802, DOI:10.1039/c5cs00466g.
- Gardner B, Stone N, Matousek P. (2016) Non-invasive chemically specific measurement of subsurface temperature in biological tissues using surface-enhanced spatially offset Raman spectroscopy, Faraday discussions, volume 187, pages 329-339, DOI:10.1039/c5fd00154d.
- Isabelle M, Dorney J, Lewis A, Lloyd GR, Old O, Shepherd N, Rodriguez-Justo M, Barr H, Lau K, Bell I. (2016) Multi-centre Raman spectral mapping of oesophageal cancer tissues: a study to assess system transferability, Faraday Discuss, volume 187, pages 87-103, DOI:10.1039/c5fd00183h. [PDF]
- Iping Petterson IP, Stone NS, Day JD, Stevens O. (2016) Developing fibre optic Raman probes for applications in clinical spectroscopy, Chem. Soc. Rev, volume 45, no. 7, pages 1919-1934, DOI:10.1039/C5CS00850F.
- Butler HJ, Ashton L, Bird B, Cinque G, Curtis K, Dorney J, Esmonde-White K, Fullwood NJ, Gardner B, Martin-Hirsch PL. (2016) Using Raman spectroscopy to characterize biological materials, Nature Protocols, volume 11, no. 4, pages 664-687, DOI:10.1038/nprot.2016.036.
- Gardner B, Matousek P, Stone N. (2016) Temperature Spatially Offset Raman Spectroscopy (T-SORS): Subsurface Chemically Specific Measurement of Temperature in Turbid Media Using Anti-Stokes Spatially Offset Raman Spectroscopy, Analytical Chemistry, volume 88, no. 1, pages 832-837, DOI:10.1021/acs.analchem.5b03360.
- Nallala J, Lloyd GR, Shepherd N, Stone N. (2016) High-resolution FTIR imaging of colon tissues for elucidation of individual cellular and histopathological features, Analyst, volume 141, no. 2, pages 630-639, DOI:10.1039/c5an01871d.
2015
- Old O, Isabelle M, Lloyd G, Kendall C, Barr H, Stone N. (2015) PTH-175 Raman mapping for pathology classification: the need for speed, Gut, volume 64, no. Suppl 1, DOI:10.1136/gutjnl-2015-309861.1063.
- Griggs R, Nallala J, Lloyd G, Kendall C, Barr H, Stone N, Shepherd N. (2015) High resolution infrared spectroscopy: Reliable, rapid diagnosis of colorectal cancer in the colon, International Journal of Surgery, volume 23, DOI:10.1016/j.ijsu.2015.07.674.
- Lloyd GR, Stone N. (2015) Method for identification of spectral targets in discrete frequency infrared spectroscopy for clinical diagnostics, Applied Spectroscopy, volume 69, no. 9, pages 1066-1073, DOI:10.1366/14-07677.
- Barr H, Old O, Almond M, Kendall C, Rhys-Lloyd G, Shetty G, Hutchings J, Stone N. (2015) Vibrational Spectroscopy: The Solution for Immediate Medical Diagnosis, Materials Today: Proceedings, volume 2, no. 3, pages 890-893, DOI:10.1016/j.matpr.2015.06.003.
- Old OJ, Lloyd G, Almond M, Kendall C, Barr H, Shore A, Stone N. (2015) NON-ENDOSCOPIC SCREENING FOR BARRETT'S OESOPHAGUS: IDENTIFYING NEOPLASIA WITH INFRARED SPECTROSCOPY, GUT, volume 64, pages A485-A485, DOI:10.1136/gutjnl-2015-309861.1062. [PDF]
- Griggs R, Nallala J, Lloyd G, Cook T, Kendall C, Barr H, Shepherd N, Stone N. (2015) HIGH RESOLUTION SPECTRAL IMAGING: NOVEL DIAGNOSTICS IN COLORECTAL CANCER, GUT, volume 64, pages A553-A554, DOI:10.1136/gutjnl-2015-309861.1214. [PDF]
- Griggs R, Nallala J, Lloyd G, Cook T, Kendall C, Barr H, Stone N, Shepherd N. (2015) EPITHELIAL MISPLACEMENT VERSUS POLYP CANCER: SHEDDING NEW LIGHT ON THE DIAGNOSTIC CONUNDRUM, GUT, volume 64, pages A553-A553, DOI:10.1136/gutjnl-2015-309861.1213. [PDF]
- Greenwood C, Clement JG, Dicken AJ, Evans JPO, Lyburn ID, Martin RM, Rogers KD, Stone N, Adams G, Zioupos P. (2015) The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue, Bone Reports, volume 3, pages 67-75, DOI:10.1016/j.bonr.2015.10.001.
- Iping Petterson IE, Day JCC, Fullwood LM, Gardner B, Stone N. (2015) Characterisation of a fibre optic Raman probe within a hypodermic needle, Anal Bioanal Chem, volume 407, no. 27, pages 8311-8320, DOI:10.1007/s00216-015-9021-7. [PDF]
- Kong K, Kendall C, Stone N, Notingher I. (2015) Raman spectroscopy for medical diagnostics - From in-vitro biofluid assays to in-vivo cancer detection, Advanced Drug Delivery Reviews, volume 89, pages 121-134, DOI:10.1016/j.addr.2015.03.009.
- Dicken AJ, Evans JPO, Rogers KD, Stone N, Greenwood C, Godber SX, Prokopiou D, Clement JG, Lyburn ID, Martin RM. (2015) X-ray diffraction from bone employing annular and semi-annular beams, Physics in Medicine and Biology, volume 60, no. 15, pages 5803-5812, DOI:10.1088/0031-9155/60/15/5803.
- Vardaki MZ, Gardner B, Stone N, Matousek P. (2015) Studying the distribution of deep Raman spectroscopy signals using liquid tissue phantoms with varying optical properties, The Analyst, volume 140, no. 15, pages 5112-5119, DOI:10.1039/c5an01118c.
- Dicken AJ, Evans JPO, Rogers KD, Greenwood C, Godber SX, Prokopiou D, Stone N, Clement JG, Lyburn I, Martin RM. (2015) Energy-dispersive X-ray diffraction using an annular beam, Optics Express, volume 23, no. 10, pages 13443-13454, DOI:10.1364/OE.23.013443.
- Byrne HJ, Baranska M, Puppels GJ, Stone N, Wood B, Gough KM, Lasch P, Heraud P, Sulé-Suso J, Sockalingum GD. (2015) Spectropathology for the next generation: Quo vadis?, Analyst.
- Wombacher R, Cornish VW, Matousek P, Stone N, Diem M, Mazur A, Lenau K, Schubert J, Bird B, Miljkoviæ M. (2015) Dear readers, Journal of Biophotonics is already going in its eighth year. The year 2014 was a very successful one. We were able to increase our 2013 impact factor from 3.099 to 3.856 showing how popular and well estab.
- Townsend D, Miljković M, Bird B, Lenau K, Old O, Almond M, Kendall C, Lloyd G, Shepherd N, Barr H. (2015) Infrared micro-spectroscopy for cyto-pathological classification of esophageal cells, Analyst.
- Nallala J, Lloyd GR, Stone N. (2015) Evaluation of different tissue de-paraffinization procedures for infrared spectral imaging, Analyst, volume 140, no. 7, pages 2369-2375, DOI:10.1039/c4an02122c.
2014
- Stone N. (2014) Raman spectroscopic tools for medical applications, Optics InfoBase Conference Papers, volume Part F38-FiO 2016, DOI:10.1364/FIO.2016.FF5A.3.
- Madami M, Fioretto D, Palombo F, Winlove CP, Edginton RS, Green E, Stone N, Caponi S. (2014) Biomechanics of fibrous proteins of the extracellular matrix.
- Almond M, Old O, Hutchings J, Kendall C, Lloyd G, Stone N, Barr H. (2014) Endoscopic Raman spectroscopy enables objective diagnosis of dysplasia in the oesophagus, BRITISH JOURNAL OF SURGERY, volume 101, pages 5-5.
- Almond LM, Old O, Stone N, Kendall C, Lloyd GR, Hutchings J, Horsnell J, Kallaway C, Barr H. (2014) Real-time disease detection using spectroscopic diagnosis, Biomedical Spectroscopy and Imaging, volume 3, pages 197-202, article no. 3.
- Stone N, Kallaway C, Almond LM, Wood J, Hutchings J, Kendall C, Barr H. (2014) Molecular Endospectroscopic Approaches, volume 9783527335138, pages 179-214, DOI:10.1002/9783527681921.ch6.
- Palombo F, Winlove CP, Edginton RS, Green E, Stone N, Caponi S, Madami M, Fioretto D. (2014) Biomechanics of fibrous proteins of the extracellular matrix studied by Brillouin scattering, J R Soc Interface, volume 11, no. 101, DOI:10.1098/rsif.2014.0739. [PDF]
- Naranjo V, Villanueva E, Lloyd GR, Stone N, Lopez-Mir F, Alcaniz M. (2014) Stained and infrared image registration as first step for cancer detection, 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014, pages 420-423, DOI:10.1109/BHI.2014.6864392.
- Wood JJ, Kendall C, Hutchings J, Lloyd GR, Stone N, Shepherd N, Day J, Cook TA. (2014) Evaluation of a confocal Raman probe for pathological diagnosis during colonoscopy, Colorectal Disease, volume 16, no. 9, pages 732-738, DOI:10.1111/codi.12664.
- Sattlecker M, Stone N, Bessant C. (2014) Current trends in machine-learning methods applied to spectroscopic cancer diagnosis, TrAC - Trends in Analytical Chemistry, volume 59, pages 17-25, DOI:10.1016/j.trac.2014.02.016.
- Old OJ, Fullwood LM, Scott R, Lloyd GR, Almond LM, Shepherd NA, Stone N, Barr H, Kendall C. (2014) Vibrational spectroscopy for cancer diagnostics, Analytical Methods, volume 6, no. 12, pages 3901-3917, DOI:10.1039/c3ay42235f.
- Scott R, Kendall C, Stone N, Rogers K. (2014) Locating microcalcifications in breast histopathology sections using micro CT and XRF mapping, Analytical Methods, volume 6, no. 12, pages 3962-3966, DOI:10.1039/c3ay42158a.
- Almond LM, Hutchings J, Lloyd G, Barr H, Shepherd N, Day J, Stevens O, Sanders S, Wadley M, Stone N. (2014) Endoscopic Raman spectroscopy enables objective diagnosis of dysplasia in Barrett's esophagus, Gastrointestinal Endoscopy, volume 79, no. 1, pages 37-45, DOI:10.1016/j.gie.2013.05.028.
- Palombo F, Madami M, Stone N, Fioretto D. (2014) Mechanical mapping with chemical specificity by confocal Brillouin and Raman microscopy, Analyst, volume 139, pages 729-733, DOI:10.1039/C3AN02168H.
2013
- Almond M, Rhys‐Lloyd G, Hutchings J, Shetty G, Shepherd N, Kendall C, Stone N, Barr H. (2013) CHAPTER 8, Detection Challenges in Clinical Diagnostics, Royal Society of Chemistry (RSC), 201-221, DOI:10.1039/9781849737302-00201.
- Almond M, Rhys-Lloyd G, Hutchings J, Shetty G, Shepherd N, Kendall C, Stone N, Barr H. (2013) The prospects for real-time raman spectroscopy for oesophageal neoplasia, RSC Detection Science, pages 201-221.
- Lloyd GR, Almond LM, Stone N, Shepherd N, Sanders S, Hutchings J, Barr H, Kendall C. (2013) Utilising non-consensus pathology measurements to improve the diagnosis of oesophageal cancer using a Raman spectroscopic probe, Analyst, volume 139, no. 2, pages 381-388, DOI:10.1039/c3an01163a.
- Kallaway C, Almond LM, Barr H, Wood J, Hutchings J, Kendall C, Stone N. (2013) Advances in the clinical application of Raman spectroscopy for cancer diagnostics, Photodiagnosis and Photodynamic Therapy, volume 10, no. 3, pages 207-219, DOI:10.1016/j.pdpdt.2013.01.008.
- Pijanka JK, Stone N, Rutter AV, Forsyth N, Sockalingum GD, Yang Y, Sulé-Suso J. (2013) Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation, Analyst, volume 138, no. 17, pages 5052-5058, DOI:10.1039/c3an00968h.
- Lloyd GR, Orr LE, Christie-Brown J, McCarthy K, Rose S, Thomas M, Stone N. (2013) Discrimination between benign, primary and secondary malignancies in lymph nodes from the head and neck utilising Raman spectroscopy and multivariate analysis, ANALYST, volume 138, no. 14, pages 3900-3908, DOI:10.1039/c2an36579k. [PDF]
- Almond LM, Hutchings J, Lloyd G, Barr H, Shepherd N, Day J, Stevens O, Sanders S, Wadley M, Stone N. (2013) Endoscopic Raman spectroscopy enables objective diagnosis of dysplasia in Barrett's esophagus, Gastrointestinal Endoscopy.
- Day JCC, Stone N. (2013) A subcutaneous Raman needle probe, Applied Spectroscopy, volume 67, no. 3, pages 349-354, DOI:10.1366/12-06651.
- Matousek P, Stone N. (2013) Recent advances in the development of Raman spectroscopy for deep non-invasive medical diagnosis, Journal of Biophotonics, volume 6, no. 1, pages 7-19, DOI:10.1002/jbio.201200141.
2012
- Kerssens MM. (2012) Study of calcification formation and disease diagnostics utilising advanced vibrational spectroscopy.
- Carey D, Shepherd N, Kendall C, Stone N, Breckon T. (2012) Visualising and grading the continuity of epithelial structures of colonic polyps, PERCEPTION, volume 41, pages 367-368.
- Horsnell J. (2012) The use of Raman spectroscopy for the intra-operative assessment of axillary lymph nodes in breast cancer.
- Carey D, Shepherd N, Kendall C, Stone N, Breckon TP, Lloyd GR. (2012) Correlating histology and spectroscopy to differentiate pathologies of the colon.
- Xie H-N, Stevenson R, Stone N, Hernandez-Santana A, Faulds K, Graham D. (2012) Tracking Bisphosphonates through a 20 mm Thick Porcine Tissue by Using Surface-Enhanced Spatially Offset Raman Spectroscopy, Angewandte Chemie, volume 124, pages 8637-8639, article no. 34.
- Almond M, Hutchings J, Kendall C, Stone N, Shepherd N, Barr H. (2012) PTU-198 Towards objective endoscopic diagnosis of early Barrett’s neoplasia using fibre-optic Raman spectroscopy, Gut, volume 61, pages A266-A266, article no. Suppl 2.
- Horsnell J, Kallaway C, Chan C, Bristol J, Court F, Stone N. (2012) 420 Real Time Assessment of Axillary Nodes Based On Molecular Differences Using Raman Spectroscopy, European Journal of Cancer, volume 48, pages S169-S169.
- Matousek P, Parker AW, Stone N. (2012) Raman analysis of tissue and/or calcifications.
- Horsnell J, Kallaway C, Chan C, Bristol J, Court F, Stone N. (2012) Real Time Assessment of Axillary Nodes Based On Molecular Differences Using Raman Spectroscopy, EUROPEAN JOURNAL OF CANCER, volume 48, pages S169-S169. [PDF]
- Horsnell J, Kallaway C, Chan C, Bristol J, Stone N. (2012) The role of Raman spectroscopy in the intraoperative assessment of axillary lymph nodes in breast cancer, BRITISH JOURNAL OF SURGERY, volume 99, pages 5-6. [PDF]
- Almond M, Hutchings J, Kendall C, Stone N, Shepherd N, Barr H. (2012) TOWARDS OBJECTIVE ENDOSCOPIC DIAGNOSIS OF EARLY BARRETT'S NEOPLASIA USING FIBRE-OPTIC RAMAN SPECTROSCOPY, GUT, volume 61, pages A266-A266, DOI:10.1136/gutjnl-2012-302514c.198. [PDF]
- Almond LM, Hutchings J, Kendall C, Day JCC, Stevens OAC, Lloyd GR, Shepherd NA, Barr H, Stone N. (2012) Assessment of a custom-built Raman spectroscopic probe for diagnosis of early oesophageal neoplasia, JOURNAL OF BIOMEDICAL OPTICS, volume 17, no. 8, article no. ARTN 081421, DOI:10.1117/1.JBO.17.8.081421. [PDF]
- Xie HN, Stevenson R, Stone N, Hernandez-Santana A, Faulds K, Graham D. (2012) Tracking bisphosphonates through a 20 mm thick porcine tissue by using surface-enhanced spatially offset raman spectroscopy, Angewandte Chemie - International Edition, volume 51, no. 34, pages 8509-8511, DOI:10.1002/anie.201203728.
- Almond LM, Hutchings J, Lloyd GR, Francis-Jones J, Stone N, Barr H, Kendall C. (2012) Preclinical evaluation of a Raman spectroscopic probe for endoscopic classification of oesophageal pathologies, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 8219, DOI:10.1117/12.919876.
- Lloyd GR, Hutchings J, Almond LM, Barr H, Kendall C, Stone N. (2012) Assessing the performance of spectroscopic models for cancer diagnostics using cross-validation and permutation testing, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 8219, DOI:10.1117/12.919864.
- Lloyd GR, Wood J, Kendall C, Cook T, Shepherd N, Stone N. (2012) Histological imaging of a human colon polyp sample using Raman spectroscopy and self organising maps, Vibrational Spectroscopy.
- Lloyd GR, Wood J, Kendall C, Cook T, Shepherd N, Stone N. (2012) Histological imaging of a human colon polyp sample using Raman spectroscopy and self organising maps, Vibrational Spectroscopy, volume 60, pages 43-49, DOI:10.1016/j.vibspec.2012.02.015.
- Horsnell JD, Smith JA, Sattlecker M, Sammon A, Christie-Brown J, Kendall C, Stone N. (2012) Raman spectroscopy--a potential new method for the intra-operative assessment of axillary lymph nodes, Surgeon, volume 10, no. 3, pages 123-127, DOI:10.1016/j.surge.2011.02.004. [PDF]
2011
- Horsnell J, Chan C, Bristol J, Court F, Stone N. (2011) Real Time Intraoperative Assessment of Axillary Lymph Nodes using Raman Spectroscopy, European Journal of Surgical Oncology (EJSO), volume 37, pages S6-S6, article no. 5.
- Erry GRG, Bazant-Hegemark F, Read MD, Stone N. (2011) Screening cervical and oesophageal tissues using optical coherence tomography, Optics InfoBase Conference Papers, DOI:10.1364/ecbo.2011.809122.
- Wood JJ, Kendall C, Lloyd GR, Shepherd NA, Cook TA, Stone N. (2011) Infrared spectroscopy to estimate the gross biochemistry associated with different colorectal pathologies, Optics InfoBase Conference Papers.
- Byrne HJ, Sockalingum GD, Stone N. (2011) Raman microscopy: Complement or competitor?, RSC Analytical Spectroscopy Series, pages 105-143.
- Stone N. (2011) Biomedical Applications of Synchrotron Infrared Microspectroscopy, Biomedical Applications of Synchrotron Infrared Microspectroscopy, Royal Society of Chemistry, 105-142.
- Almond LM, Hutchings J, Kendall C, Stone N, Barr H. (2011) Mapping of the distal oesophagus using fibre-optic Raman spectroscopy, BRITISH JOURNAL OF SURGERY, volume 98, pages 35-35. [PDF]
- Wood J, Kendall C, Stone N, Shepherd N, Cook T. (2011) Evaluation of a Raman probe for pathological diagnosis with potential use at colonoscopy, BRITISH JOURNAL OF SURGERY, volume 98, pages 5-5. [PDF]
- Wood J, Kendall C, Stone N, Shepherd N, Cook T. (2011) The use of infrared spectroscopy to estimate the gross biochemistry associated with different colorectal pathologies, BRITISH JOURNAL OF SURGERY, volume 98, pages 82-83. [PDF]
- Wood JJ, Kendall C, Hutchings J, Lloyd G, Stone N, Shepherd N, Day J, Cook T. (2011) EVALUATION OF A RAMAN PROBE FOR PATHOLOGICAL DIAGNOSIS AT COLONOSCOPY, GUT, volume 60, DOI:10.1136/gut.2011.239301.157. [PDF]
- Wood JJ, Kendall C, Stone N, Shepherd N, Cook T. (2011) THE USE OF INFRARED SPECTROSCOPY TO PROVIDE AN ESTIMATION OF THE GROSS BIOCHEMISTRY ASSOCIATED WITH COLORECTAL PATHOLOGIES, GUT, volume 60, pages A54-A54, DOI:10.1136/gut.2011.239301.106. [PDF]
- Almond M, Hutchings J, Kendall C, Stone N, Day J, Shepherd N, Barr H. (2011) TOWARDS REAL-TIME 'BIOCHEMICAL ENDOSCOPY' FOR DIAGNOSIS OF EARLY BARRETT'S NEOPLASIA, GUT, volume 60, DOI:10.1136/gut.2011.239301.356. [PDF]
- Horsnell J, Stonelake P, Shetty G, Kendall C, Hutchings J, Stone N. (2011) Assessment of axillary lymph nodes using raman spectroscopy-intraoperative use is possible, BRITISH JOURNAL OF SURGERY, volume 98, pages 26-26. [PDF]
- Almond LM, Hutchings J, Barr H, Day J, Stone N, Kendall C. (2011) Development of fibreoptic Raman probes for in vivo diagnosis of upper gastrointestinal cancers, Spectroscopy Europe, volume 23, no. 3, pages 6-12.
- Erry GRG, Bazant-Hegemark F, Read MD, Stone N. (2011) Screening cervical and oesophageal tissues using optical coherence tomography, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 8091, DOI:10.1117/12.889678.
- Jerjes WK, Upile T, Wong BJ, Betz CS, Sterenborg HJ, Witjes MJ, Berg K, Van Veen R, Biel MA, El-Naggar AK. (2011) The future of medical diagnostics: Review paper, Head and Neck Oncology, volume 3, no. 1, DOI:10.1186/1758-3284-3-38.
- Upile T, Jerjes WK, Sterenborg HJ, Wong BJ, El-Naggar AK, Ilgner JF, Sandison A, Witjes MJ, Biel MA, Van Veen R. (2011) At the frontiers of surgery: Review, Head and Neck Oncology, volume 3, no. 1, DOI:10.1186/1758-3284-3-7.
- Sattlecker M, Stone N, Smith J, Bessant C. (2011) Assessment of robustness and transferability of classification models built for cancer diagnostics using Raman spectroscopy, Journal of Raman Spectroscopy, volume 42, no. 5, pages 897-903, DOI:10.1002/jrs.2798.
- Stone N, Kerssens M, Lloyd GR, Faulds K, Graham D, Matousek P. (2011) Surface enhanced spatially offset Raman spectroscopic (SESORS) imaging - the next dimension, Chemical Science, volume 2, no. 4, pages 776-780, DOI:10.1039/c0sc00570c.
- Sattlecker M, Baker R, Stone N, Bessant C. (2011) Support vector machine ensembles for breast cancer type prediction from mid-FTIR micro-calcification spectra, Chemometrics and Intelligent Laboratory Systems, volume 107, no. 2, pages 363-370, DOI:10.1016/j.chemolab.2011.05.007.
- Wood JJ, Kendall C, Lloyd GR, Shepherd NA, Cook TA, Stone N. (2011) Infrared spectroscopy to estimate the gross biochemistry associated with different colorectal pathologies, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 8087, DOI:10.1117/12.889605.
- Almond LM, Hutchings J, Shepherd N, Barr H, Stone N, Kendall C. (2011) Raman spectroscopy: a potential tool for early objective diagnosis of neoplasia in the oesophagus, J Biophotonics, volume 4, no. 10, pages 685-695, DOI:10.1002/jbio.201100041. [PDF]
- Barr H, Kendall C, Hutchings J, Bazant-Hegemark F, Shepherd N, Stone N. (2011) Rapid endoscopic identification and destruction of degenerating Barrett's mucosal neoplasia, Surgeon, volume 9, no. 3, pages 119-123, DOI:10.1016/j.surge.2010.08.003. [PDF]
- Kendall C, Hutchings J, Barr H, Shepherd N, Stone N. (2011) Exploiting the diagnostic potential of biomolecular fingerprinting with vibrational spectroscopy, Faraday Discuss, volume 149, pages 279-290, DOI:10.1039/c005379a. [PDF]
- Humphreys L, Orme RML, Moore P, Charaklias N, Sahgal N, Pont NP, Magan N, Stone N, Kendall CA. (2011) Electronic nose analysis of bronchoalveolar lavage fluid, Eur J Clin Invest, volume 41, no. 1, pages 52-58, DOI:10.1111/j.1365-2362.2010.02376.x. [PDF]
2010
- Orr L, Kendall C, Hutchings J, Isabelle M, Horsnell J, Stone N. (2010) Raman spectroscopy as a tool for the identification and differentiation of neoplasias contained within lymph nodes of the head and neck, Head & Neck Oncology, volume 2, no. Suppl 1, DOI:10.1186/1758-3284-2-s1-o4.
- Byrne HJ, Sockalingum GD, Stone N. (2010) Chapter 4, Biomedical Applications of Synchrotron Infrared Microspectroscopy, Royal Society of Chemistry (RSC), 105-143, DOI:10.1039/9781849731997-00105.
- Moss D. (2010) Dedication.
- Orr LE. (2010) Raman Spectroscopy of Biological Tissue for Application in Optical Diagnosis of Malignancy.
- Stone N, Kendall CA. (2010) Raman spectroscopy for early cancer detection, diagnosis and elucidation of disease-specific biochemical changes, Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields, Springer Berlin Heidelberg, 315-346.
- Rogers KD, Baker R, Stone N. (2010) Breast calcification: the’Cinderella’breast element?, Breast Cancer Research, volume 12, pages P36-P36, article no. Suppl 1.
- Horsnell J, Stonelake P, Shetty G, Christie-Brown J, Kendall C, Stone N. (2010) Raman Spectroscopy: A Promising Method of Assessing Axillary Lymph Nodes Even in the Presence of Blue Dye, European Journal of Surgical Oncology (EJSO), volume 36, pages 1111-1111, article no. 11.
- Stone N. (2010) Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields, Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields, Springer.
- Rogers KD, Baker R, Stone N. (2010) Breast calcification: the 'Cinderella' breast element?, BREAST CANCER RESEARCH, volume 12, pages S11-S12, DOI:10.1186/bcr2533. [PDF]
- Grimbergen MCM, Van Swol CFP, Kendall C, Verdaasdonk RM, Stone N, Bosch JLHR. (2010) Signal-to-noise contribution of principal component loads in reconstructed near-infrared Raman tissue spectra, Applied Spectroscopy, volume 64, no. 1, pages 8-14, DOI:10.1366/000370210790572052.
- Aneesh A, Považay B, Hofer B, Zhang EZ, Kendall C, Laufer J, Popov S, Glittenberg C, Binder S, Stone N. (2010) Optimizing penetration depth, contrast, and resolution in 3D dermatologic OCT, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 7554, DOI:10.1117/12.843243.
- Hutchings J, Kendall C, Shepherd N, Barr H, Day J, Stone N. (2010) Ultra-low spatial resolution Raman mapping using a novel fibre optic probe, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 7560, DOI:10.1117/12.858803.
- Stone N, Faulds K, Graham D, Matousek P. (2010) Prospects of deep Raman spectroscopy for noninvasive detection of conjugated surface enhanced resonance Raman scattering nanoparticles buried within 25 mm of mammalian tissue, Analytical Chemistry, volume 82, no. 10, pages 3969-3973, DOI:10.1021/ac100039c.
- Pijanka JK, Stone N, Cinque G, Yang Y, Kohler A, Wehbe K, Frogley M, Parkes G, Parkes J, Dumas P. (2010) FTIR microspectroscopy of stained cells and tissues. Application in cancer diagnosis, Spectroscopy, volume 24, no. 1-2, pages 73-78, DOI:10.3233/SPE-2010-0419.
- Hughes OR, Stone N, Kraft M, Arens C, Birchall MA. (2010) Optical and molecular techniques to identify tumor margins within the larynx, Head and Neck, volume 32, no. 11, pages 1544-1553, DOI:10.1002/hed.21321.
- Hutchings J, Kendall C, Shepherd N, Barr H, Stone N. (2010) Evaluation of linear discriminant analysis for automated Raman histological mapping of esophageal high-grade dysplasia, J Biomed Opt, volume 15, no. 6, DOI:10.1117/1.3512244. [PDF]
- Horsnell J, Stonelake P, Christie-Brown J, Shetty G, Hutchings J, Kendall C, Stone N. (2010) Raman spectroscopy--a new method for the intra-operative assessment of axillary lymph nodes, Analyst, volume 135, no. 12, pages 3042-3047, DOI:10.1039/c0an00527d. [PDF]
- Kendall C, Day J, Hutchings J, Smith B, Shepherd N, Barr H, Stone N. (2010) Evaluation of Raman probe for oesophageal cancer diagnostics, Analyst, volume 135, no. 12, pages 3038-3041, DOI:10.1039/c0an00536c. [PDF]
- Kerssens MM, Matousek P, Rogers K, Stone N. (2010) Towards a safe non-invasive method for evaluating the carbonate substitution levels of hydroxyapatite (HAP) in micro-calcifications found in breast tissue, Analyst, volume 135, no. 12, pages 3156-3161, DOI:10.1039/c0an00565g. [PDF]
- Baker R, Rogers KD, Shepherd N, Stone N. (2010) New relationships between breast microcalcifications and cancer, Br J Cancer, volume 103, no. 7, pages 1034-1039, DOI:10.1038/sj.bjc.6605873. [PDF]
- Isabelle M, Rogers K, Stone N. (2010) Correlation mapping: rapid method for identification of histological features and pathological classification in mid infrared spectroscopic images of lymph nodes, J Biomed Opt, volume 15, no. 2, DOI:10.1117/1.3386061. [PDF]
- Sattlecker M, Bessant C, Smith J, Stone N. (2010) Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics, Analyst, volume 135, no. 5, pages 895-901, DOI:10.1039/b920229c. [PDF]
- Orr LE, Christie-Brown J, Hutchings JC, McCarthy K, Rose S, Thomas M, Stone N. (2010) Raman spectroscopy as a tool for the identification and differentiation of neoplasias contained within lymph nodes of the head and neck, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 7548, DOI:10.1117/12.848784.
2009
- Upile T, Jerjes W, Sterenborg HJCM, El-Naggar AK, Sandison A, Witjes MJH, Biel MA, Bigio I, Wong BJF, Gillenwater A. (2009) Head & neck optical diagnostics: vision of the future of surgery, Head & neck oncology, volume 1, DOI:10.1186/1758-3284-1-25.
- Upile T, Jerjes W, Sterenborg HJCM, El-Naggar AK, Sandison A, Witjes MJH, Biel MA, Bigio I, Wong BJF, Gillenwater A. (2009) Head & Neck Oncology, Head & Neck, volume 1, pages P15-P15, article no. 1.
- Stone N. (2009) Recent Advances in Gastroenterology 11, Recent Advances in Gastroenterology 11, Royal Society of Medicine Press, 15-27.
- Filik J, Stone N. (2009) Investigation into the protein composition of human tear fluid using centrifugal filters and drop coating deposition Raman spectroscopy, Journal of Raman Spectroscopy, volume 40, no. 2, pages 218-224, DOI:10.1002/jrs.2113.
- Grimbergen MCM, van Swol CFP, van Moorselaar RJA, Uff J, Mahadevan-Jansen A, Stone N. (2009) Raman spectroscopy of bladder tissue in the presence of 5-aminolevulinic acid, Journal of Photochemistry and Photobiology B: Biology, volume 95, no. 3, pages 170-176, DOI:10.1016/j.jphotobiol.2009.03.002.
- Grimbergen MCM, Van Swol CFP, Draga ROP, Van Diest P, Verdaasdonk RM, Stone N, Bosch JHLR. (2009) Bladder cancer diagnosis during cystoscopy using Raman spectroscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 7161, DOI:10.1117/12.807811.
- Matousek P, Stone N. (2009) Emerging concepts in deep Raman spectroscopy of biological tissue, Analyst, volume 134, no. 6, pages 1058-1066, DOI:10.1039/b821100k.
- Day JCC, Bennett R, Smith B, Kendall C, Hutchings J, Meaden GM, Born C, Yu S, Stone N. (2009) A miniature confocal Raman probe for endoscopic use, Physics in Medicine and Biology, volume 54, no. 23, pages 7077-7087, DOI:10.1088/0031-9155/54/23/003.
- Kendall C, Isabelle M, Bazant-Hegemark F, Hutchings J, Orr L, Babrah J, Baker R, Stone N. (2009) Vibrational spectroscopy: a clinical tool for cancer diagnostics, Analyst, volume 134, no. 6, pages 1029-1045, DOI:10.1039/b822130h. [PDF]
- Hutchings J, Kendall C, Smith B, Shepherd N, Barr H, Stone N. (2009) The potential for histological screening using a combination of rapid Raman mapping and principal component analysis, J Biophotonics, volume 2, no. 1-2, pages 91-103, DOI:10.1002/jbio.200810070. [PDF]
- Babrah J, McCarthy K, Lush RJ, Rye AD, Bessant C, Stone N. (2009) Fourier transform infrared spectroscopic studies of T-cell lymphoma, B-cell lymphoid and myeloid leukaemia cell lines, Analyst, volume 134, no. 4, pages 763-768, DOI:10.1039/b807967f. [PDF]
- Bazant-Hegemark F, Stone N. (2009) Towards automated classification of clinical optical coherence tomography data of dense tissues, Lasers Med Sci, volume 24, no. 4, pages 627-638, DOI:10.1007/s10103-008-0615-6. [PDF]
2008
- Sarantavgas G. (2008) Investigation of a fibre-optic Fizeau interferometer configuration and coherent fibre-optic imaging bundles for optical coherence tomography.
- Filik J, Stone N. (2008) Raman point mapping of tear ferning patterns, Biomedical Optics (BiOS) 2008, pages 685309-685309.
- Hutchings J, Kendall C, Shepherd N, Barr H, Smith B, Stone N. (2008) Rapid Raman microscopic imaging for potential histological screening, Biomedical Optics (BiOS) 2008, pages 685305-685305.
- Stone N, Kendall C, Barr H. (2008) Raman spectroscopy as a potential tool for early diagnosis of malignancies in esophageal and bladder tissues, Handbook of Vibrational Spectroscopy.
- Stone N, Baker R, Prieto CH, Matousek P. (2008) Novel Raman signal recovery from deeply buried tissue components (Invited Paper)[6853A-51], PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, volume 6853, pages 6853-6853.
- Barr H, Stone N, Ding DCD, Kendall C, Bird-Lieberman EL, Esophagus FRCBS, Bronner MP, Overholt BF, Taylor SL, others. (2008) Bibliography Current World Literature Vol 25 No 5 September 2009, Photodiagnosis and Photodynamic Therapy, volume 5, pages 187-190.
- Holmes J, Hattersley S, Stone N, Bazant-Hegemark F, Barr H. (2008) Multi-channel Fourier domain OCT system with superior lateral resolution for biomedical applications [6847-23], PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, volume 6847, pages 6847-6847.
- Stone N. (2008) Vibrational Spectroscopy for Medical Diagnosis, Vibrational Spectroscopy for Medical Diagnosis, Wiley.
- Filik J, Stone N. (2008) Raman point mapping of tear ferning patterns - art. no. 685309, BIOMEDICAL OPTICAL SPECTROSCOPY, volume 6853, pages 85309-85309, DOI:10.1117/12.786441. [PDF]
- Holmes J, Hattersley S, Stone N, Bazant-Hegemark F, Barr H. (2008) Multi-channel Fourier domain OCT system with superior lateral resolution for biomedical applications, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6847, DOI:10.1117/12.761655.
- Hutchings J, Kendall C, Shepherd N, Barr H, Smith B, Stone N. (2008) Rapid Raman microscopic imaging for potential histological screening, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6853, DOI:10.1117/12.786440.
- Filik J, Stone N. (2008) Raman point mapping of tear ferning patterns, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6853, DOI:10.1117/12.786441.
- Stone N, Baker R, Prieto CH, Matousek P. (2008) Novel Raman signal recovery from deeply buried tissue components, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6853, DOI:10.1117/12.786442.
- Isabelle M, Stone N, Barr H, Vipond M, Shepherd N, Rogers K. (2008) Lymph node pathology using optical spectroscopy in cancer diagnostics, Spectroscopy, volume 22, no. 2-3, pages 97-104, DOI:10.1155/2008/871940.
- Bird B, Miljkovic M, Romeo MJ, Smith J, Stone N, George MW, Diem M. (2008) Infrared micro-spectral imaging: Distinction of tissue types in axillary lymph node histology, BMC Clinical Pathology, volume 8, no. 1, DOI:10.1186/1472-6890-8-8.
- Keller MD, Kanter EM, Lieber CA, Majumder SK, Hutchings J, Ellis DL, Beaven RB, Stone N, Mahadevan-Jansen A. (2008) Detecting temporal and spatial effects of epithelial cancers with Raman spectroscopy, Disease Markers, volume 25, no. 6, pages 323-337, DOI:10.1155/2008/230307.
- Bazant-Hegemark F, Meglinski I, Kandamany N, Monk B, Stone N. (2008) Optical coherence tomography: a potential tool for unsupervised prediction of treatment response for Port-Wine Stains, Photodiagnosis Photodyn Ther, volume 5, no. 3, pages 191-197, DOI:10.1016/j.pdpdt.2008.09.001. [PDF]
- Reyes-Goddard JM, Barr H, Stone N. (2008) Surface enhanced Raman scattering of herpes simplex virus in tear film, Photodiagnosis Photodyn Ther, volume 5, no. 1, pages 42-49, DOI:10.1016/j.pdpdt.2008.01.002. [PDF]
- Barr H, Stone N, Ding DCD, Kendall C. (2008) Current practice in management of high-grade dysplasia in Barrett's oesophagus: the real problem, Photodiagnosis Photodyn Ther, volume 5, no. 1, pages 38-41, DOI:10.1016/j.pdpdt.2008.01.004. [PDF]
- Bazant-Hegemark F, Edey K, Swingler GR, Read MD, Stone N. (2008) Review: optical micrometer resolution scanning for non-invasive grading of precancer in the human uterine cervix, Technol Cancer Res Treat, volume 7, no. 6, pages 483-496, DOI:10.1177/153303460800700610. [PDF]
- Das K, Kendall C, Isabelle M, Fowler C, Christie-Brown J, Stone N. (2008) FTIR of touch imprint cytology: a novel tissue diagnostic technique, J Photochem Photobiol B, volume 92, no. 3, pages 160-164, DOI:10.1016/j.jphotobiol.2008.05.012. [PDF]
- Bazant-Hegemark F, Stone N. (2008) Near real-time classification of optical coherence tomography data using principal components fed linear discriminant analysis, J Biomed Opt, volume 13, no. 3, DOI:10.1117/1.2931079. [PDF]
- Stone N, Matousek P. (2008) Advanced transmission Raman spectroscopy: a promising tool for breast disease diagnosis, Cancer Res, volume 68, no. 11, pages 4424-4430, DOI:10.1158/0008-5472.CAN-07-6557. [PDF]
- Filik J, Stone N. (2008) Analysis of human tear fluid by Raman spectroscopy, Anal Chim Acta, volume 616, no. 2, pages 177-184, DOI:10.1016/j.aca.2008.04.036. [PDF]
2007
- Archer JK, Sudworth CD, Williams R, How T, Stone N, Mann D, Black RA. (2007) Improvements in Alzheimer' Disease Diagnosis using Principal Component Analysis (PCA) in Combination with Raman Spectroscopy, Diagnostic Optical Spectroscopy in Biomedicine IV, DOI:10.1364/ecbo.2007.6628_37.
- Bazant-Hegemark F, Stone N, Read MD, McCarthy K, Wang RK. (2007) Optical coherence tomography (OCT) imaging and computer aided diagnosis of human cervical tissue specimens, Optics InfoBase Conference Papers, DOI:10.1364/ecbo.2007.6627_65.
- Aning JJ, Isabelle M, Uff J, Ritchie AWS, Gilbert HW, Stone N. (2007) FTIR biochemical imaging of the prostate: an in vitro proof of concept study, European Conference on Biomedical Optics, pages 66280F-66280F.
- Stone N. (2007) Modelling narrow groove pipe welding of X100 pipeline steel.
- Matousek P, Stone N. (2007) Prospects for the diagnosis of breast cancer using transmission Raman spectroscopy, J Biomed Opt.
- Aning J, Uff J, Ritchie A, Gilbert H, Stone N. (2007) 237 STAIN-FREE BIOCHEMICAL IMAGING OF THE PROSTATE UTILISING FTIR MICROSPECTROSCOPY: A PROOF OF CONCEPT STUDY, European Urology Supplements, volume 6, pages 82-82, article no. 2.
- Aning JJ, Isabelle M, Uff J, Ritchie AWS, Gilbert HW, Stone N. (2007) FTIR biochemical imaging of the prostate: An in-vitro proof of concept study, Optics InfoBase Conference Papers.
- Baker RN, Rogers KD, Shepherd N, Stone N. (2007) Analysis of breast tissue calcifications using FTIR spectroscopy, Optics InfoBase Conference Papers.
- Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C, Stone N. (2007) FT-infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell lines, Optics InfoBase Conference Papers.
- Archer JKJ, Sudworth CD, Williams R, How T, Stone N, Mann D, Black RA. (2007) Improvements in alzheimer's disease diagnosis using principal component analysis (PCA) in combination with raman spectroscopy, Optics InfoBase Conference Papers.
- Bazant-Hegemark F, Stone N, Read MD, McCarthy K, Wang RK. (2007) Optical coherence tomography (OCT) imaging and computer aided diagnosis of human cervical tissue specimens, Optics InfoBase Conference Papers.
- Babrah J, Lush R, Rye A, McCarthy K, Bessant C, Stone N. (2007) Fourier transform infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell lines, BRITISH JOURNAL OF HAEMATOLOGY, volume 137, pages 4-4. [PDF]
- Aning JJ, Stone N, Gilbert HW, Ritchie AWS. (2007) Stain-free biochemical imaging of the prostate utilising FTIR microspectroscopy: a proof of concept study, BJU INTERNATIONAL, volume 99, pages 29-29. [PDF]
- Anino J, Uff J, Ritchie A, Gilbert H, Stone N. (2007) Stain-free biochemical imaging of the prostate utilising FTIR microspectroscopy: A proof of concept study, EUROPEAN UROLOGY SUPPLEMENTS, volume 6, no. 2, pages 82-82, DOI:10.1016/S1569-9056(07)60236-X. [PDF]
- Bazant-Hegemark F, Stone N, Read MD, McCarthy K, Wang RK. (2007) Optical Coherence Tomography (OCT) imaging and computer aided diagnosis of human cervical tissue specimens, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6627.
- Archer JKJ, Sudworth CD, Williams R, How T, Stone N, Mann D, Black RA. (2007) Improvements in Alzheimer's disease diagnosis using principal component analysis (PCA) in combination with Raman spectroscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6628.
- Matousek P, Stone N. (2007) Prospects for the diagnosis of breast cancer by noninvasive probing of calcifications using transmission Raman spectroscopy, Journal of Biomedical Optics, volume 12, no. 2, DOI:10.1117/1.2718934.
- Das K, Stone N, Kendall C, Fowler C, Christie-Brown J. (2007) Role of Fourier transform infrared spectroscopy (FTIR) in the diagnosis of parathyroid pathology, Photodiagnosis and Photodynamic Therapy, volume 4, no. 2, pages 124-129, DOI:10.1016/j.pdpdt.2007.01.006.
- Bazant-Hegemark F, Stone N, McKenzie G, Holmes J. (2007) Optical coherence tomography aids cancer detection, Biophotonics International, volume 14, no. 11, pages 46-47.
- Baker RN, Rogers KD, Shepherd N, Stone N. (2007) Analysis of breast tissue calcifications using FTIR spectroscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6628, DOI:10.1364/ecbo.2007.6628_18.
- Aning JJ, Isabelle M, Uff J, Ritchie AWS, Gilbert HW, Stone N. (2007) FTIR biochemical imaging of the prostate: An in-vitro proof of concept study, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6628.
- Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C, Stone N. (2007) FT-infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell lines, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6628, DOI:10.1364/ecbo.2007.6628_28.
- Stone N, Baker R, Rogers K, Parker AW, Matousek P. (2007) Subsurface probing of calcifications with spatially offset Raman spectroscopy (SORS): future possibilities for the diagnosis of breast cancer, Analyst, volume 132, no. 9, pages 899-905, DOI:10.1039/b705029a. [PDF]
- Filik J, Stone N. (2007) Drop coating deposition Raman spectroscopy of protein mixtures, Analyst, volume 132, no. 6, pages 544-550, DOI:10.1039/b701541k. [PDF]
- Taylor JC, Kendall CA, Stone N, Cook TA. (2007) Optical adjuncts for enhanced colonoscopic diagnosis, Br J Surg, volume 94, no. 1, pages 6-16, DOI:10.1002/bjs.5628. [PDF]
- Baker R, Matousek P, Ronayne KL, Parker AW, Rogers K, Stone N. (2007) Depth profiling of calcifications in breast tissue using picosecond Kerr-gated Raman spectroscopy, Analyst, volume 132, no. 1, pages 48-53, DOI:10.1039/b614388a. [PDF]
- Stone N, Hart Prieto MC, Crow P, Uff J, Ritchie AW. (2007) The use of Raman spectroscopy to provide an estimation of the gross biochemistry associated with urological pathologies, Anal Bioanal Chem, volume 387, no. 5, pages 1657-1668, DOI:10.1007/s00216-006-0937-9. [PDF]
2006
- Stone N, Kaiser K, White RD. (2006) Autotuning of a pid controller for an active vibration suppression device for the treatment of essential tremor, American Society of Mechanical Engineers, Dynamic Systems and Control Division (Publication) DSC, DOI:10.1115/IMECE2006-14138.
- Stone N, Prieto MCH, Kendall CA, Shetty G, Barr H. (2006) Raman spectroscopic biochemical mapping of tissues [6093-29], PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, volume 6093, pages 60930U-60930U.
- Subramanian K, Stone N, Kendall C, Brown JC, McCarthy K, Bristol J, Chan YH. (2006) Infrared spectroscopy: a novel tool to aid classification of DCIS [6093-18], PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, volume 6093, pages 60930J-60930J.
- Baker RN, Smith J, Rogers KD, Stone N. (2006) Vibrational spectroscopic analysis of breast calcifications and surrounding tissue [6093-32], PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, volume 6093, pages 60930X-60930X.
- Sherry G, Kendall C, Shephard N, Stone N, Barr H. (2006) Novel technique in understanding the sequence of biochemical changes in carcinogenesis of esophagus, GASTROENTEROLOGY, volume 130, pages A311-A311.
- Das K, Stone N, Kendall C, Fowler C, Christie-Brown J. (2006) Fourier transform infrared spectroscopy (FTIR) of parathyroid pathology.
- Grimbergen MCM, van Swol CFP, van Moorselaar RJA, Stone N, others. (2006) Feasibility of Raman spectroscopy in vitro after 5-ALA-based fluorescence diagnosis in the bladder, Biomedical Optics 2006, pages 60781D-60781D.
- Taylor JC, Kendall CA, Shepherd NA, Stone N, Cook TA. (2006) Raman spectroscopic mapping to evaluate the biochemical changes associated with the development of colorectal neoplasia, GUT, volume 55, pages A85-A85. [PDF]
- Subramanian K, Kendall C, Stone N, Brown JC, McCarthy K, Bristol J, Chan YH. (2006) Raman spectroscopic analysis of atypical proliferative lesions of the breast, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6088, DOI:10.1117/12.644553.
- Barr H, Kendall C, Bazant-Hegemark F, Stone N. (2006) Endoscopic photodynamic therapy for oesophageal disease, Photodiagnosis and Photodynamic Therapy, volume 3, no. 2, pages 102-105, DOI:10.1016/j.pdpdt.2006.03.008.
- Stone N, Prieto MCH, Kendall CA, Shetty G, Barr H. (2006) Raman spectroscopic biochemical mapping of tissues, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6093, DOI:10.1117/12.644178.
- Baker RN, Smith J, Rogers KD, Stone N. (2006) Vibrational spectroscopic analysis of breast calcifications and surrounding tissue, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6093, DOI:10.1117/12.644497.
- Subramanian K, Stone N, Kendall C, Brown JC, McCarthy K, Bristol J, Chan YH. (2006) Infrared spectroscopy a novel tool to aid classification of DCIS, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 6093, DOI:10.1117/12.644512.
- Sowa MG, Smith MSD, Kendall C, Bock ER, Alex CTKO, Choo-Smith LPI, Stone N. (2006) Semi-parametric estimation in the compositional modeling of multicomponent systems from Raman spectroscopic data, Applied Spectroscopy, volume 60, no. 8, pages 877-883, DOI:10.1366/000370206778062147.
- Das K, Stone N, Kendall C, Fowler C, Christie-Brown J. (2006) Raman spectroscopy of parathyroid tissue pathology, Lasers Med Sci, volume 21, no. 4, pages 192-197, DOI:10.1007/s10103-006-0397-7. [PDF]
- Barr H, Kendall C, Bazant-Hegemark F, Moayyedi P, Shetty G, Stone N. (2006) Endoscopic screening and surveillance for Barrett's esophagus--clinical implications, MedGenMed, volume 8, no. 2. [PDF]
- Barr H, Kendall C, Bazant-Hegemark F, Moayyedi P, Shetty G, Stone N. (2006) Endoscopic screening and surveillance for Barrett's esophagus--clinical implications, MedGenMed, volume 8, no. 2. [PDF]
- Shetty G, Kendall C, Shepherd N, Stone N, Barr H. (2006) Raman spectroscopy: elucidation of biochemical changes in carcinogenesis of oesophagus, Br J Cancer, volume 94, no. 10, pages 1460-1464, DOI:10.1038/sj.bjc.6603102. [PDF]
2005
- Smith J, Kendall C, Sammon AM, Christie-Brown J, Mandalia T, Stone N. (2005) Raman Spectroscopy is Sensitive and Specific in the Detection of Lymph Node Metastases in Breast Cancer, Diagnostic Optical Spectroscopy in Biomedicine III, DOI:10.1364/ecbo.2005.tuc2.
- Smith J, Kendall C, Sammon AM, Christie-Brown J, Mandalia T, Stone N. (2005) Raman spectroscopy is sensitive and specific in the detection of lymph node metastases in breast cancer [5862-02], PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, volume 5862, pages 586202-586202.
- Shetty G, Kendall C, Shepherd N, Stone N, Barr H. (2005) Biochemical mapping of esophageal carcinogenesis with Raman spectroscopy, GASTROENTEROLOGY, volume 128, pages A252-A252.
- Van Swol C, Grimbergen M, Van Moorselaar R, Stone N, others. (2005) Feasibility of Raman Spectroscopy after 5-ALA Based Fluorescence Diagnosis in the Bladder, Australasian Physical & Engineering Sciences in Medicine, volume 28, pages 300-300, article no. 4.
- Fitzmaurice M, Haka AA, Volynskaya Z, Motz JT, Gardecki JA, Nazemi J, Wang N, Klein N, Shenk R, Woletz J. (2005) Raman spectroscopy: development of clinical applications for breast cancer diagnosis, European Conference on Biomedical Optics 2005, pages 586201-586201.
- Consuelo M, Prieto H, Matousek P, Towrie M, Parker AW, Wright M, Ritchie AW, Stone N. (2005) Use of picosecond Kerr-gated Raman spectroscopy to suppress signals from both surface and deep layers in bladder and prostate tissue, Journal of Biomedical Optics, volume 10, pages 044006-1, article no. 4.
- GEETA S, Kendall C, Warren B, Geboes K, Shepherd N, Stone N, Barr H. (2005) Potential endoscopic technique for early diagnosis of Barrett’s malignancy-Raman spectroscopy, Gastroenterology, volume 128, pages A90-A90.
- Smith J, Kendall C, Sammon AM, Christie-Brown J, Mandalia T, Stone N. (2005) Raman spectroscopy is sensitive and specific in the detection of lymph node metastases in breast cancer, Optics InfoBase Conference Papers.
- Prieto MCH, Wright M, Ritchie AW, Stone N. (2005) The use of Raman spectroscopy to determine the biochemical basis to pathologies within the prostate, BJU INTERNATIONAL, volume 95, pages 17-17. [PDF]
- Smith J, Kendall C, Christie-Brown J, Chan C, Sammon A, Barr H, Stone N. (2005) Raman spectroscopy is a sensitive, specific and rapid technique for the assessment of lymph node metastases in breast carcinoma, BRITISH JOURNAL OF SURGERY, volume 92, pages 70-70. [PDF]
- Shetty G, Kendall C, Warren B, Geboes K, Shepherd N, Stone N, Barr H. (2005) Raman spectroscopy: Illumination of biochemical changes in carcinogenesis with potential endoscopic application, GUT, volume 54, pages A51-A51. [PDF]
- Prieto MCH, Wright M, Ritchie AW, Stone N. (2005) The use of Raman spectroscopy to determine the biochemical basis to pathologies within the bladder, BJU INTERNATIONAL, volume 95, pages 21-21. [PDF]
- Smith J, Kendall C, Christie-Brown J, Sammon A, Barr H, Stone N. (2005) Optical assessment of axillary lymph nodes in breast carcinoma, BREAST CANCER RESEARCH AND TREATMENT, volume 94, pages S42-S43. [PDF]
- Goyal A, Hart-Prieto C, Stone N, Chopra M, Cooper A. (2005) Using Raman microspectroscopy to detect lycopene uptake into prostate cancer cells in vitro, PROCEEDINGS OF THE NUTRITION SOCIETY, volume 64, pages 71A-71A. [PDF]
- Reyes-Goddard JM, Barr H, Stone N. (2005) Photodiagnosis using Raman and surface enhanced Raman scattering of bodily fluids, Photodiagnosis and Photodynamic Therapy, volume 2, no. 3, pages 223-233, DOI:10.1016/S1572-1000(05)00066-9.
- Smith J, Kendall C, Sammon AM, Christie-Brown J, Mandalia T, Stone N. (2005) Raman spectroscopy is sensitive and specific in the detection of lymph node metastases in breast cancer, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 5862, pages 1-7.
- Prieto MCH, Matousek P, Towrie M, Parker AW, Wright M, Ritchie AW, Stone N. (2005) Use of picosecond Kerr-gated Raman spectroscopy to suppress signals from both surface and deep layers in bladder and prostate tissue, J Biomed Opt, volume 10, no. 4, DOI:10.1117/1.1991848. [PDF]
- Crow P, Barrass B, Kendall C, Hart-Prieto M, Wright M, Persad R, Stone N. (2005) The use of Raman spectroscopy to differentiate between different prostatic adenocarcinoma cell lines, Br J Cancer, volume 92, no. 12, pages 2166-2170, DOI:10.1038/sj.bjc.6602638. [PDF]
- Crow P, Molckovsky A, Stone N, Uff J, Wilson B, WongKeeSong L-M. (2005) Assessment of fiberoptic near-infrared raman spectroscopy for diagnosis of bladder and prostate cancer, Urology, volume 65, no. 6, pages 1126-1130, DOI:10.1016/j.urology.2004.12.058. [PDF]
- Barr H, Stone N, Rembacken B. (2005) Endoscopic therapy for Barrett's oesophagus, Gut, volume 54, no. 6, pages 875-884, DOI:10.1136/gut.2004.047118. [PDF]
2004
- Crow P, Molckovsky A, Uff J, Stone N, Wilson B, Wongkeesong L-M. (2004) 259: Fibre-Optic Raman Spectrsocopy: The Prospects for in Vivo Diagnosis of Bladder and Prostate Cancer, Journal of Urology, volume 171, no. 4, DOI:10.1016/s0022-5347(18)37521-9.
- Crow P, Barrass B, Prieto MH, Kendall C, Wright M, Stone N. (2004) 431: The Use of Raman Spectroscopy to Differentiate Between Different Cultured Prostate Cancer Cell Lines in vitro, Journal of Urology, volume 171, no. 4, DOI:10.1016/s0022-5347(18)37693-6.
- Crow P, Barrass B, Prieto MH, Kendall C, Wright M, Stone N. (2004) The use of Raman spectroscopy to differentiate between different cultured prostate cancer cell lines in vitro, Journal of Urology, volume 171, pages 114-114.
- Crow P, Molckovsky A, Uff J, Stone N, Wilson B, Wongkeesong LM. (2004) Fibre-optic Raman spectrsocopy: the prospects for in vivo diagnosis of bladder and prostate cancer, Journal of Urology, volume 171, pages 68-68.
- Smith JA, Christie-Brown J, Sammon AN, Chan C, Stone N. (2004) Microscopic Raman spectroscopy for the study of lymph node metastases in breast cancer, Microscopy and Microanalysis, volume 10, pages 1312-1313, article no. S02.
- Bhargava R, Bird MB, Bonnet MA, Briddon SJ, Bruni P, Clarke DT, Dovbeshko GI, Dumas P, Feld MS, Finney WF. (2004) Dr R. Allibone, NHS. UK Dr F. Bahrami, CCLRC, UK Mr BR Baker, University of California. Los Angeles. USA Professor H. Barr. Gloucestershire Royal Hospital. UK, Applications of Spectroscopy to Biomedical Problems: University of Nottingham, September 1-3, 2003, volume 126, pages 317-318, article no. 126.
- Smith J, Kendall C, Christie-Brown J, Sammon AN, Barr H, Stone N. (2004) Raman spectroscopy for lymph node assessment in breast cancer, BRITISH JOURNAL OF SURGERY, volume 91, no. 9, pages 1227-1227. [PDF]
- Smith JA, Kendall C, Christie-Brown J, Sammon AM, Barr H, Stone N. (2004) Optical biopsy is highly specific for positive lymph node classification in breast cancer, BRITISH JOURNAL OF SURGERY, volume 91, pages 118-119. [PDF]
- Prieto MCH, Crow P, Kendall C, Uff J, Wright M, Ritchie A, Stone N. (2004) Urological applications of Raman spectroscopy for improved malignant diagnostics, Proceedings of SPIE - The International Society for Optical Engineering, volume 5321, pages 57-68, DOI:10.1117/12.528907.
- Smith J, Christie-Brown J, Sammon AM, Stone N. (2004) Axillary lymph node analysis using raman spectroscopy, Proceedings of SPIE - The International Society for Optical Engineering, volume 5321, pages 69-74, DOI:10.1117/12.528916.
- Sulé-Suso J, Forster A, Zholobenko V, Stone N, El Haj A. (2004) Effects of CaCl
2 and MgCl2 on Fourier Transform Infrared Spectra of Lung Cancer Cells, Applied Spectroscopy, volume 58, no. 1, pages 61-67, DOI:10.1366/000370204322729487. - Barr H, Kendall C, Stone N. (2004) The light solution for Barrett's oesophagus: Photodiagnosis and photodynamic therapy for columnar-lined oesophagus, Photodiagnosis and Photodynamic Therapy, volume 1, no. 1, pages 75-84, DOI:10.1016/S1572-1000(04)00011-0.
- Crow P, Uff JS, Farmer JA, Wright MP, Stone N. (2004) The use of Raman spectroscopy to identify and characterize transitional cell carcinoma in vitro, BJU Int, volume 93, no. 9, pages 1232-1236, DOI:10.1111/j.1464-410X.2004.04852.x. [PDF]
- Stone N, Kendall C, Smith J, Crow P, Barr H. (2004) Raman spectroscopy for identification of epithelial cancers, Faraday Discuss, volume 126, pages 141-157, DOI:10.1039/b304992b. [PDF]
2003
- Reyes-Goddard J, Woodman A, Stone N, Barr H, Creighton JA, Saito Y, Batchelder D. (2003) Surface enhanced Raman scattering of the tear film, Diagnostic Optical Spectroscopy in Biomedicine II, DOI:10.1364/ecbo.2003.5141_219.
- Smith J, Kendall C, Christie-Brown J, Sammon A, Stone N. (2003) Raman Spectroscopy in the assessment of breast cancer and axillary lymph node metastases, Optics InfoBase Conference Papers, pages 305-309.
- Kendall C, McCloskey K, Stone N, Barr H, Greenhalgh D. (2003) Multiphoton imaging in the detection of malignancy in the oesophagus, Optics InfoBase Conference Papers, pages 51-55.
- Reyes-Goddard J, Woodman A, Stone N, Barr H, Creighton JA, Saito Y, Batchelder D. (2003) Surface enhanced Raman scattering of the tear film, Optics InfoBase Conference Papers, pages 219-229.
- Kendall C, Stone N, Shepherd N, Barr H. (2003) Raman spectral mapping for the illumination of biochemical changes associated with malignancy in the oesophagus, Optics InfoBase Conference Papers, pages 237-248.
- Crow P, Stone N, Kendall C, Uff J, Ritchie A, Wright M. (2003) Optical diagnostics in bladder cancer: the use of Raman spectroscopy to differentiate between bladder pathologies in vitro, Journal of Urology, volume 169, pages 225-225.
- Sulé-Suso J, Zholobenko V, Stone N, El Haj A. (2003) 30 Effects of chemotherapy on lung cancer cell lines measured with Fourier transform infrared spectroscopy, Lung Cancer, volume 41, pages S281-S281.
- Smith J, Kendall C, Christie-Brown J, Sammon A, Stonea N. (2003) Raman Spectroscopy in the assessment of breast cancer and axillary lymph node metastases, European Conference on Biomedical Optics, pages 5141\_305-5141\_305.
- Kendall C, Stone N, Shepherd N, Barr H. (2003) Raman spectral mapping for the illumination of biochemical changes associated with malignancy in the oesophagus, European Conference on Biomedical Optics, pages 5141\_237-5141\_237.
- Kendall C, McCloskey K, Stone N, Barr H, Greenhalgh D. (2003) Multiphoton imaging in the detection of malignancy in the oesophagus, European Conference on Biomedical Optics, pages 5139\_51-5139\_51.
- Smith J, Stone N, Kendall C, Christie-Brown J, Shepherd N, Sammon A, Barr H. (2003) Raman spectroscopy: a novel optical technique for the diagnosis and management of carcinoma of the oesophagus and breast, and lymph node metastases, BRITISH JOURNAL OF SURGERY, volume 90, no. 5, pages 637-637. [PDF]
- Chandratreya NV, Stone N, Kendall C, Glass RE, Barr H, Shepherd N. (2003) Near infrared Raman spectroscopy a new tool for detection and classification of colonic disease, BRITISH JOURNAL OF SURGERY, volume 90, pages 66-66. [PDF]
- Kendall C, Stone N, Shepherd N, Barr H. (2003) Raman spectral mapping for the illumination of biochemical changes associated with malignancy in the oesophagus, Proceedings of SPIE - The International Society for Optical Engineering, volume 5141, pages 237-248, DOI:10.1117/12.500438.
- Kendall C, McCloskey K, Stone N, Barr H, Greenhalgh D. (2003) Multiphoton imaging in the detection of malignancy in the oesophagus, Proceedings of SPIE - The International Society for Optical Engineering, volume 5139, pages 51-55, DOI:10.1117/12.500486.
- Reyes-Goddard J, Woodman A, Stone N, Barr H, Creighton JA, Saito Y, Batchelder D. (2003) Surface enhanced Raman scattering of the tear film, Proceedings of SPIE - The International Society for Optical Engineering, volume 5141, pages 219-229, DOI:10.1117/12.500643.
- Smith J, Kendall C, Christie-Brown J, Sammon A, Stone N. (2003) Raman spectroscopy in the assessment of breast cancer and axillary lymph node metastases, Proceedings of SPIE - The International Society for Optical Engineering, volume 5141, pages 305-309, DOI:10.1117/12.500472.
- Crow P, Stone N, Kendall CA, Persad RA, Wright MPJ. (2003) Optical diagnostics in urology: current applications and future prospects, BJU Int, volume 92, no. 4, pages 400-407, DOI:10.1046/j.1464-410x.2003.04368.x. [PDF]
- Kendall C, Stone N, Shepherd N, Geboes K, Warren B, Bennett R, Barr H. (2003) Raman spectroscopy, a potential tool for the objective identification and classification of neoplasia in Barrett's oesophagus, J Pathol, volume 200, no. 5, pages 602-609, DOI:10.1002/path.1376. [PDF]
- Stone N. (2003) Standardizing dosimetry in esophageal PDT: an argument for use of centering devices and removal of misleading units, Technol Cancer Res Treat, volume 2, no. 4, pages 333-338, DOI:10.1177/153303460300200408. [PDF]
- Smith J, Kendall C, Sammon A, Christie-Brown J, Stone N. (2003) Raman spectral mapping in the assessment of axillary lymph nodes in breast cancer, Technol Cancer Res Treat, volume 2, no. 4, pages 327-332, DOI:10.1177/153303460300200407. [PDF]
- Crow P, Stone N, Kendall CA, Uff JS, Farmer JAM, Barr H, Wright MPJ. (2003) The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro, Br J Cancer, volume 89, no. 1, pages 106-108, DOI:10.1038/sj.bjc.6601059. [PDF]
- Barr H, Kendall C, Stone N. (2003) Photodynamic therapy for esophageal cancer: a useful and realistic option, Technol Cancer Res Treat, volume 2, no. 1, pages 65-76, DOI:10.1177/153303460300200108. [PDF]
2002
- Crow P, Wright M, Persad R, Kendall C, Stone N. (2002) Evaluation of Raman spectroscopy to provide a real time, optical method for discrimination between normal and abnormal tissue in the bladder, European Urology Open Science, volume 1, no. 1, DOI:10.1016/s1569-9056(02)80305-0.
- Crow P, Kendall C, Wright M, Persad R, Ritchie A, Stone N. (2002) The use of Raman spectroscopy to distinguish between normal tissue, carcinoma in situ and TCC within the bladder, Br J Urol, volume 90, pages 71-71.
- Crow P, Ritchie A, Wright M, Kendall C, Stone N. (2002) Evaluation of Raman spectroscopy to provide a real time, optical method for discrimination between normal and abnormal tissue in the prostate, European Urology Supplements, volume 1, pages 92-92, article no. 1.
- Kendall C, Barr H, Shepherd N, Stone N. (2002) Optimum procedure for construction of spectral classification algorithms for medical diagnosis, Proceedings of SPIE - The International Society for Optical Engineering, volume 4614, pages 152-158, DOI:10.1117/12.460791.
- Stone N, Kendall C, Chandratreya N, Shepherd N, Barr H. (2002) Near-infrared Raman spectroscopy for detection and classification of gastrointestinal disease, Proceedings of SPIE - The International Society for Optical Engineering, volume 4614, pages 117-126, DOI:10.1117/12.460788.
- Stone N, Kendall C, Shepherd N, Crow P, Barr H. (2002) Near-infrared Raman spectroscopy for the classification of epithelial pre-cancers and cancers, Journal of Raman Spectroscopy, volume 33, no. 7, pages 564-573, DOI:10.1002/jrs.882.
- Barr H, Kendall C, Reyes-Goddard J, Stone N. (2002) Clinical aspects of photodynamic therapy, Sci Prog, volume 85, no. Pt 2, pages 131-150, DOI:10.3184/003685002783238825. [PDF]
2001
- Stone N. (2001) Raman spectroscopy of biological tissue for application in optical diagnosis of malignancy.
- Barr H, Dix AJ, Kendall C, Stone N. (2001) The potential role for photodynamic therapy in the management of upper gastrointestinal disease, Alimentary pharmacology & therapeutics, volume 15, pages 311-321, article no. 3.
- Barr H, Dix AJ, Kendall C, Stone N. (2001) Review article: the potential role for photodynamic therapy in the management of upper gastrointestinal disease, Aliment Pharmacol Ther, volume 15, no. 3, pages 311-321, DOI:10.1046/j.1365-2036.2001.00936.x. [PDF]
2000
- Stavroulaki P, Stone N, Fulljames C, Barr H, Birchall M. (2000) Raman spectroscopy for early detection of laryngeal malignancy: preliminary results, Clinical Otolaryngology & Allied Sciences, volume 25, pages 91-92, article no. 1.
- Schut TCB, Stone N, Kendall CA, Barr H, Bruining HA, Puppels GJ. (2000) Progress in the detection of neoplastic progress and cancer by Raman spectroscopy, BiOS 2000 The International Symposium on Biomedical Optics, pages 106-113.
- Stone N, Stavroulaki P, Fulljames CA, Birchall M, Barr H. (2000) Raman spectroscopy: A diagnostic tool for detection of early malignant changes in the larynx, BIOMEDICAL SPECTROSCOPY: VIBRATIONAL SPECTROSCOPY AND OTHER NOVEL TECHNIQUES, volume 3918, pages 120-128, DOI:10.1117/12.384933. [PDF]
- Stone N, Stavroulaki P, Kendall C, Birchall M, Barr H. (2000) Raman spectroscopy for early detection of laryngeal malignancy: Preliminary results, Laryngoscope, volume 110, no. 10 I, pages 1756-1763, DOI:10.1097/00005537-200010000-00037.
- Kendall C, Schut TB, Stone N, Stravroulaki P, Puppels G, Barr H. (2000) Raman spectroscopy for the diagnosis of dysplasia in columnar and squamous epithelium, Proceedings of SPIE - The International Society for Optical Engineering, volume 4161, pages 131-137, DOI:10.1117/12.409321.
- Stone N, Stavroulaki P, Kendall C, Birchall M, Barr H. (2000) Raman spectroscopy for early detection of laryngeal malignancy: preliminary results, Laryngoscope, volume 110, no. 10 Pt 1, pages 1756-1763, DOI:10.1097/00005537-200010000-00037. [PDF]
1999
- Tan WC, Fulljames C, Stone N, Dix AJ, Shepherd N, Roberts DJH, Brown SB, Krasner N, Barr H. (1999) Photodynamic therapy using 5-aminolaevulinic acid for oesophageal adenocarcinoma associated with Barrett's metaplasia, Journal of Photochemistry and Photobiology B: Biology, volume 53, no. 1-3, pages 75-80, DOI:10.1016/S1011-1344(99)00129-3.
- Fulljames C, Stone N, Bennett D, Barr H. (1999) Beyond white light endoscopy - The prospect for endoscopie optical biopsy, Italian Journal of Gastroenterology and Hepatology, volume 31, no. 8, pages 688-694.
- Fulljames C, Stone N, Bennett D, Barr H. (1999) Beyond white light endoscopy--the prospect for endoscopic optical biopsy, Ital J Gastroenterol Hepatol, volume 31, no. 8, pages 695-704. [PDF]
1998
- Barr H, Dix T, Stone N. (1998) Optical spectroscopy for the early diagnosis of gastrointestinal malignancy, Lasers in Medical Science, volume 13, no. 1, pages 3-13, DOI:10.1007/BF00592955.
1996
- Stone N, Barr H, Ahmad R. (1996) Optical measurements on human synovial fluid and its relevance to pathology, Proceedings of SPIE - The International Society for Optical Engineering, volume 2927, pages 67-77, DOI:10.1117/12.260655.
1993
- Marshall P, Stone N. (1993) Fibre-matrix interface transverse tensile debonding, Journal of materials science letters, volume 12, pages 218-219, article no. 4.
Further information
Personal Homepage
I lead the Biomedical Spectroscopy team exploring the novel use of novel vibrational spectroscopic techniques for point of care testing, advanced spectral histopathology and rapid in vivo diagnostics. Here we explore the power of light to measure the changes in the molecular constituents of cells and tissues as disease develops. This can be achieved in short timescales, in a minimally invasive manner using fibre optics or deep scattering methods.
Further details of my research projects can be found at the Biomedical Imaging Research page.
Basic science, translated from bench to bedside.
I have worked for most of my career at the interface between physics, engineering and medicine. I have worked been working to pioneer the field of novel optical diagnostics within the clinical environment, working closely at the clinical/academic/commercial interface to pull-through novel technologies to be used where they have most clinical need. I have worked in multi-sectoral consortia to develop clinical tools for in vivo Raman endoscopy (RECaD), SERS diagnostics (Mesophotonics), in vivo optical coherence tomography (Michelson Diagnostics), novel infrared histopathology (MINERVA). I was recently appointed to the position of Professor of Biomedical Imaging and Biosensing at the University of Exeter, leading me to relinquish the positions of Consultant Clinical Scientist and Head of the Biophotonics Research Unit at Gloucestershire Hospitals and Professor of Biophotonics at Cranfield University. There I established an internationally recognised research unit within a district general hospital pioneering novel optical techniques for diagnostics and therapeutics.
I currently hold the positions of Honorary Consultant Clinical Scientist at Gloucestershire Hospitals NHS Foundation Trust and at the Royal Devon and Exeter Foundation Trust.
Funded research projects
Projects for which I was the Principal or Co-Investigator:
2013-2016 EPSRC Healthcare Technology £971,955
2013-2016 EPSRC Healthcare Technology £748,432 (PI)
2012-2015 STFC Research Studentship £38,500 (PI)
2012-2015 LINC Research Studentship £60,000 (PI)
2009-2012 BCSP Research Studentship £45,000 (PI)
2012-2016 Minerva – FP7 €7.4M (€578,000)
2012-2015 NIHR i4i Raman Needle Probe £700,846 (£531,000) (PI)
2012-2015 Cobalt Professorship £105,000 (PI)
2010-2012 Royal College of Surgeons
2011 Commercial Consultancy Income £24,000
2011-2014 Gloucestershire NHS Research Fellowship (DEng) £30,000
2011-2013 McIntyre Clinical Research Fellowship £100,000
2010-2012 BUPA Foundation £96,016 (PI)
2010-2011 NIHR i4i FPD 1 Subcutaneous Raman £97,434
2010-2011 CRUK £25,000
2010-2011 Bowel Disease Research Foundation £30,000
2009-2012 NIHR Fellowship (in group) Raman molecular cancer diagnostics £139,221
2009-2012 STFC Research Studentship £45,000 (PI)
2009-2012 LINC Research Studentship £60,000 (PI)
2009-2012 BCSP Research Studentship £45,000
2007-2012 DH Career Scientist Research Fellowship (NIHR Senior Research Fellow) £452K (PI)
2007-2009 Dti OCT at 1 Micron: Improved ContRast for Optimal detection of Neoplasm (OMICRON) £ 553K (£55K)
2006-2009 IPEM Research Fellowship (PhD) £75K.
2006-2009 CPMS Pump Prime Fund PhD Studentship (Vascular OCT) £60K. (PI)
2006-2007 Cobalt Appeal Fund Research Bursary £24K (DM prostate cancer diagnostics).
2005-2008 Dti Nano-photonics SERS applications for clinical diagnosis. £2M (£175K).
2005-2009 (IN GROUP) Royal Society Dorothy Hodgkins Research Fellowship £200K.
2005 Co-applicant CCLRC ULTRA (Ultrasensitive Lifesciences Time Resolved Analysis).
2005-2006 CCLRC Rutherford Appleton Laboratory £90K.
2005 Co-applicant Framework 6: Biomedical applications of IR synchrotron radiation.
2007-2008 Cobalt Appeal Fund Research Bursary (Breast) £40K. (PI)
2005-2008 LINC Robert Dalton Research Fellowship (PhD) £60K. (PI)
2005-2008 CPMS Pump Prime Fund PhD Studentship (Lymph nodes) £60K. (PI)
2004 Cobalt Appeal Fund, £110K, Equipment funding, ‘Enhanced Pathological Diagnosis of Cancers and Pre-Cancers.’ (PI)
2004-2007 CPMS Pump Prime Fund PhD Studentship (OCT) £60K. (PI)
2004 CCLRC Rutherford Appleton Laboratory £75K. (PI)
2004-2008 Health Technology Device Funding (DoH) £ 290 K. (PI)
2004-2005 NHS Research Programme Funding £43K.
2004-2005 Cobalt Appeal Fund Research Bursary (Urology) £20K.
2004 Council for the Central Laboratory of the Research Councils (CCLRC) £18K.
2003-2004 NHS Research Programme Funding £24K.
2002 Royal College of Ophthalmologists £5K.
2002-2006 NHS R&D Postdoctoral Research Fellowship £ 180 K. (PI)
2001-2002 Research Contract, £ 27.3 K, ‘Raman Spectroscopy for Detection of Cancer in the Oesophagus.’ (PI)
2001-2002 South West Regional Development Agency Infrastructure, £29.6 K ‘Cranfield Medical Research Centre. (PI)
1998-2001 MEDLINK (DTI & Department of Health), £928 K ‘Raman Endoscope for Cancer Detection’ (in the oesophagus).
2000-2001 South West Regional Development Agency Infrastructure, £44.8 K ‘Cranfield Medical Research Centre.’
1995-1998 Winfield Research Bursary, £48 K ‘Tissue Viability Studies in the Anterior Cruciate Ligament with Optical Spectroscopy Techniques.’ (PI)
1996 Barnwood Trust Equipment Grant, £10 K ‘Tissue diagnostics with optical spectroscopy. (PI)
Facilities
CCLRC - Rutherford Appleton Laboratory / Daresbury Synchrotron / Diamond Light Source / Aladdin Light Source (Wisconsin)
Invited Presentations
Invited presentations since Jan 2008:
2008 Invited speaker Gordon Conference, Boston, USA.
2008 Invited speaker International Conference on Raman Spectroscopy, Uxbridge, UK.
2008 National Cancer Research Institute, ‘Molecular imaging without stains using Raman spectroscopy, a potential histopathological tool.’
2008 Invited speaker SPEC Brazil ‘Early Cancer Analysis and Diagnostics Using Raman Spectroscopy.’
2009 Invited speaker International Conference on Applied Vibrational Spectroscopy, Melbourne, Australia.
2009 Invited speaker Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Louisville, Kentucky, USA
2009 Invited IPEM Managing Grants
2009 Invited BMLA Conference – Optical Diagnostics Keynote
2009 Invited Dundee opening new biomedical interface centre.
2009 Invited BC-ISMRM Cardiff
2009 Lecture European Biophotonics Summer School (Ireland)
2009 Invited NIHR Faculty Trainees Conference
2009 Invited NHS Employers
2009 Invited NHS CSO Conference
2010 Invited SMI Imaging in Oncology
2010 Invited LSF Annual Users Meeting
2010 Invited European Laser Association International Symposium, Taragona Spain.
2010 Invited Strathclyde University lecture programme.
2010 Invited Royal College of Radiologists ASM
2010 Invited Renishaw spectroscopy workshop
2010 Invited Deep Raman talk IRDG Manchester
2010 Invited speaker Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Rayleigh, North Carolina, USA – Vibrational Spectroscopy of Lymph nodes
2010 Invited speaker Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Rayleigh, North Carolina, USA – Blood, sweat and tears, DCDRS
2010 Invited International Cancer Colloquium – St Andrews
2011 Invited CSO Modernising Scientific Careers Higher Education Breifing Event
2011 Invited Parliamentary Science Committee
2011 Invited Healthcare Innovation EXPO Keynote speaker
2011 Invited International Conferenece on Biomaterials Science, Tsukuba, Japan (Cancelled).
2011 Invited UK Chapter of the Society for Applied Spectroscopy inaugural meeting.
2011 International Conference on Applied Vibrational Spectroscopy, Sonoma, USA.
2011 Invited iNets SW.
2011 Invited NIHR Grants workshop mentor.
2011 European Medical Physics and Engineering Conference, Dublin. 2011 – Best Oral Presentations Prize
2011 Invited KTN Network - Advances in non-invasive biosensing techniques for medical diagnostics and monitoring.
2011 Invited Nano meets spectroscopy, NPL.
2011 Invited speaker Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Reno, Nevada, USA – SESORS.
2012 Invited Long term conditions – Effective Cancer Care, Monitoring and Treatment.
2012 Invited UK SAS FTIR London
2012 Invited speaker ICORS Bangalore.
2012 Invited Diamond Synchrotron Users Meeting
2012 Invited Renishaw Users meeting
2012 Invited speaker RSC session – SciX – St Louis
2012 Invited Aladdin Wisconsin Synchrotron Users Meeting
2012 Invited Photonex UK
2013 Invited SciX Milwaukee
2013 Invited Aladdin Wisconsin Synchrotron Users Meeting
2014 Invited Pittcon, Chicago
2014 Invited Plenary International Conference of Raman spectroscopy, Jena.
2014 Invited Plenary SPEC Shining Light on Disease, Krakow.
Contributions to the Community
Institute of Physics and Engineering in Medicine (IPEM)
Vice President (Academic) (2013- )
Chair Academic Advisory Group (2011-2014)
Council Member (2011-2014)
Vice-Chair Academic Advisory Group (2010-2011)
Director of Science Board (2008-2010)
Council Member / Trustee (2008-2010)
Vice-Chair Scientific Engineering and Technology Committee (2006-2008)
Council Elected Member / Trustee (2003-2006)
IPEM Academic Development Group. (2003-2010)
IPEM Scientific Committee (2004-2006)
IPEM Communications Working Group (2006-2007)
Society of Applied Spectroscopy (International)
Meggars Award Committee Member (2013- )
Chair Lippincott Award Committee (2013- )
RSC Analyst Editorial Advisory Board (2013- )
British Standards Institute Non-Ionising Radiation Safety Committee(EPL/76). (2003-2009)
British Medical Laser Association Executive. (2002- )
Head and Neck Optical Diagnostics Society Council Member (2008- )
Diagnostic Application of Synchrotron Infrared Microscopy (DASIM) Executive (EU Framework 6 Programme) (2006-2008)
STFC Biomedical Network Member
Review panel for Soleil Synchrotron (2009- )
Conference Organisation since 2008
2008 Programme Committee and Session Chair for Advanced Laser Technologies Focused on Biomedical Optics, SPIE.
2008 Programme committee for SPEC 2008 Brazil.
2008 Organising Committee for Institute of Physics and Engineering in Medicine Annual Scientific Conference, Bath.
2009 Organising Committee for Institute of Physics and Engineering in Medicine MPEC, Liverpool.
2010 Chair of Session and Member of Programme Committee for International Conference on Biomedical Vibrational Spectroscopy, BiOS 2010, SPIE, San Francisco, USA.
2010 Co-Chair of SPEC 2010 Manchester.
2010 Organising Committee for Institute of Physics and Engineering in Medicine MPEC, Nottingham.
2011 Section Chair (5 half day sessions) for Biomedical and Bioanalytical Spectroscopy at FACSS, Reno.
2011 Section Co-chair British Medical Laser Association Photodiagnostics and OCT Session organizer and chair.
2011 Session Chair and International Committee for European Medical Physics and Engineering Conference, Dublin.
2012 Chair of Session and Member of Programme Committee for International Conference on Biomedical Vibrational Spectroscopy, BiOS 2010, SPIE, San Francisco, USA.
2012 International Advisory Board. SPEC Shedding Light on Disease, Thailand.
2012 Programme Committee Photonex.
2013 British Medical Laser Association Scientific Committee, Annual meeting, Manchester.
2014 International Advisory Board. SPEC Shedding Light on Disease, Krakow.
Memberships
- Fellow of the Institution of Physics and Engineering in Medicine (IPEM).
- Member of the Society for Applied Spectroscopy.
- Registered Clinical Scientist [CS 3557]
- Chartered Scientist [PEM 108 002563]
- Fellow of the Head and Neck Optical Diagnostic Society
- Member of the British Medical Laser Association.
- Member of the Coblentz Society.
Prizes Since 2008:
2009 The Chief Scientific Officers National R&D Award.
2010 Extraordinary Scientists – Top 100 Scientists in Health.
2011 European Medical Physics and Engineering Conference – Presidents’s Prize for Best Oral Presentation.
2012 FACSS/SAS/Coblentz/ISA Award at ICORS 2012 in Bangalore.
2013 Highly Commended NHS Innovation Challenge Prizes - Earlier Cancer Diagnosis and Improving Diagnostic Investigation.