Mass Spectrometry
Our Facility houses an Agilent HPLC system, a Thermo Orbitrap Ascend Multiomics LC-MS, an Agilent HPLC-Triple Quadrupole MS, an Agilent GC-QTOF and a Trajan HDX automation system operated in a dedicated lab by our Facility specialists.
The Mass Spectrometry Facility provides an analytical service for biologically relevant “small molecules” and proteins, including: targeted quantitative analysis of specific compounds (pharmaceuticals, metabolites, lipids, volatile compounds), untargeted metabolite profiling (metabolomics) and quantitative global protein/phospho-protein profiling (proteomics and phospho-proteomics). Our state-of-the-art Thermo Orbitrap Ascend MS system and Advance LEAP HDX automation platform have recently added hydrogen-deuterium exchange mass spectrometry (HDX-MS) analyses to our suite of capabilities.
The facility supports researchers across the University and the wider community by undertaking internal and external collaborations and contract research. Our Facility can develop bespoke methods, support collaborators with data analysis and assist researchers in the interpretation and understanding of the data acquired using our systems.
Take a look at our “How to access the Facility” and “Equipment and Capabilities” tabs for more details.