Spinout: SENISCA – Reversing Cellular Ageing
SENISCA was spun-out of University of Exeter (UoE) research and capitalises on decades of expertise in the RNA and ageing biology spaces. We have identified a novel (and druggable) molecular mechanism underpinning cellular senescence; a key driver of ageing and age-related disease. Our novel concept offers the potential for the development of new generation of treatments targeting a range of currently intractable age-related conditions. Our small molecule and RNA therapeutic drugs are designed to target a wide range of tissue types, for the treatment of diseases such as lung fibrosis, osteoarthritis and macular degeneration, which are common in older people. Our interventions will target these diseases at their roots, rather than their symptoms. We are forward thinking to reverse cellular ageing.
I have found it incredibly rewarding to see our empirical research translating towards the clinic. We hope our new technologies will be able to make a real difference to the health and quality of life of our ageing population.
Professor Lorna Harries
Professor of Molecular Genetics
