Masters Degrees

MSc Genomic Medicine

Please note: This page is for 2027 entry. Click here for 2026 entry.

UCAS code 1234
Duration 1 year full time
2 years part time
3 years part time
Entry year 2026
Campus St Luke's Campus
Typical offer

View full entry requirements

2:2 Honours degree

Contextual offers

Why study MSc Genomic Medicine at Exeter?

  • Taught by world-leading academics in genomics research, including multifactorial traits, rare disorders, pharmacogenomics and epigenetics.
  • Developed by Health Education England and is aligned with their vision to prepare the NHS for the legacy of the 100,000 Genomes Project
  • Learn how genomics is applied to clinical medicine
  • Develop skills and knowledge in bioinformatics, genomic sequencing, rare disorders, infectious disease, cancer, epigenomics and more
  • You will study a rich curriculum examining theory, research, policy and practice in the field of genomic medicine
  • Learn to analyse real life genetic data as part of our Bioinformatics modules and the data-based research dissertation
  • If you’re interested in improving your data analysis and learning genetics and genomics why not study our MSc in Genomic Medicine (Data Science)
  • Benefit from our flexible study options – study full or part time, with a variety of optional modules to complement your career needs
  • NHS employees in England can apply for funding from NHS England (NHSE; formerly Health Education England) to undertake up to a maximum of four modules (PGCert) in the first instance.

Apply online

Apply for individual modules 2026/27

Fast Track (current Exeter students)

Accreditation of prior learning (APL)

Open Days

Get a prospectus

Contact

Programme Director: Dr Jess Tyrrell

Web: Enquire online

Phone: +44 (0)1392 72 72 72

Dr Jess Tyrrell describes the MSc Genomic Medicine at the University of Exeter Medical School.

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Top 10 in the UK for our world-leading and internationally excellent Clinical Medicine research

Based on 4* + 3* research in REF 2021

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Our Public Health research is 11th in the UK for research power

Submitted to UoA2 Public Health, Health Services and Primary Care. REF 2021

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Major capital investment in new buildings and state-of-the-art facilities

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Limited number of NHSE funded places for NHS professionals

Course content

Genomic medicine is no longer a vision for the future. In the UK, the NHS aims to make genomic sequencing part of routine care. The University of Exeter has invested heavily in genomics, with extensive expertise in cutting-edge technologies and world-leading genomic research.

We are one of several universities to offer this prestigious programme and our flexible curriculum enables you to study cutting-edge genomics and how it is applied to clinical medicine. This MSc programme has been developed by Health Education England (now NHSE) and will educate and train students to work in this rapidly evolving field. The MSc provides students with opportunities to work with real-life genomics data and gain analytical skills. For those wishing to enhance their data skills we also offer the MSc Genomic Medicine (Data Science) which combines the University of Exeter’s world leading expertise in Genomics and Health Data Science.

The Genomic Medicine MSc has a number of compulsory modules including ‘Fundamentals in Human Genetics and Genomics’, which begins by covering basic concepts in genetics and molecular biology. You’ll also choose from a range of optional modules including 'Genomics of Common and Rare Diseases', 'Infectious Disease', 'Molecular Pathology of Cancer' and 'Counselling Skills for Genomics'.

Awards

This MSc course can be studied on a full time basis over one year or over two or three years (part time), which may suit applicants who are already working full time. The programme is divided into units of study called ‘modules’ which are assigned a number of ‘credits’. To gain a Masters qualification, you will need to complete 180 credits at level seven. The credit rating of a module is proportional to the total workload, with one credit being nominally equivalent to 10 hours of work, a 15-credit module being equivalent to 150 hours of work and a full Masters degree being equivalent to approximately 1,800 hours of work.

Genomic Medicine award structure

It is also possible to exit with a PGCert after completing 60 credits of taught modules or a PGDip after completing 120 credits of taught modules. The list of modules below shows which are compulsory.

Contact Days‌

View the draft timetable of contact days for 2026-27

‌Please note: this timetable is a draft and subject to change

The last contact day and assessment deadline for the programme will be earlier than the actual end date of your registration with the University, to allow a period of time at the end of your active studies for further support and mitigation, if needed.

Please note: if student numbers are too low for a module to run as planned, we may change the delivery approach. This could include moving from in-person teaching to online learning, with optional on-campus sessions where appropriate.

The modules below provide examples of what you can expect to learn on this degree course based on recent academic teaching. The precise modules available to you in future years may vary depending on staff availability and research interests, new topics of study, timetabling and student demand.

Please note that the module information displayed here is subject to change.

The full MSc course comprises 180 credits made up from seven core modules: six taught modules of 15 credits each and one research module of either 60 or 30 credits. A range of optional modules is available for you to design your own learning experience to complement your career needs, and to complete the full 180 credits required.

It is also possible to exit with a PGCert after completing 60 credits of taught modules or a PGDip after completing 120 credits of taught modules.

75-105 credits of compulsory modules, 75-105 credits of optional modules (subject to choosing 180 credits in total). You must select modules as follows:

Compulsory choice 2 - select 30-60 credits from this group.

Optional 1 - select 75-105 credits from this group. Module HPDM045 requires on-campus attendance. HPDM046Z will run subject to sufficient interest.

Compulsory modules

CodeModuleCredits
Compulsory 1
Omics Techniques and Their Application to Genomic Medicine15
Genomics of Common and Rare Inherited Diseases15
Fundamentals in Human Genetics and Genomics15
Compulsory Choice 2
Research Project - Data60
Research Project - Literature30

HPDM036: Omics Techniques and Their Application to Genomic Medicine

This module explores state-of-the-art genomic technologies used for DNA sequencing, including targeted approaches, whole exome sequencing and whole genome sequencing, together with RNA sequencing and other technologies used to investigate genomic variation in clinical settings. You will gain an understanding of the principles and applications of these highly parallel sequencing technologies and array-based methodologies used in genomic medicine. The module introduces key bioinformatics approaches for the analysis and interpretation of genomic data. Together with the Introduction to Human Genetics and Genomics module, this module provides a foundation for the subsequent Bioinformatics, Interpretation, Statistics and Data Quality Assurance module. In addition, the module introduces the application of RNA sequencing and other molecular approaches to estimate gene and protein expression, including the study of mRNA, microRNAs and long non-coding RNAs. The module also provides a comprehensive introduction to epigenomics, proteomics and metabolomics, highlighting their roles in the functional interpretation of genomic data and the discovery of disease biomarkers. Applications of omics approaches in areas such as cancer genomics and infectious disease research will be explored to illustrate how integrated genomic data can inform disease mechanisms, diagnostics and personalised medicine.

View an example full module specification

HPDM037: Genomics of Common and Rare Inherited Diseases

This module is available either via blended learning with contact days on-campus supported by online learning, or as fully distance learning via our online platform.

This module explores the genetic basis of common and rare inherited disorders. The principles and practice of medical genetics and genomics, and the management and treatment of patients and their families will be discussed. Utilizing exemplars, the module demonstrates the clinical utility of genomic data in healthcare settings. You will learn about contemporary approaches used to identify genetic causes of disease, with a focus on rare inherited diseases.

The module will also address the integration of genomic data into clinical pathways, emphasizing the impact of advances in genomic technologies on patient care. The role of genomics in care pathways will be explored from both patient and family perspectives, as well as the diagnostic and therapeutic implications of genomic data. Additionally, you will learn to identify patients with unmet diagnostic needs who may benefit from exome or genome sequencing and will be introduced to the complexities of interpreting genomic data in clinical contexts. The module will also cover key initiatives such as the development of genomic medicine services, and the infrastructure supporting incorporation of genomic testing into the NHS.

View an example full module specification

HPDM082A: Fundamentals in Human Genetics and Genomics

This module will start by covering the fundamentals of nucleic acid structure and function, including changes during the cell cycle. Following this, you will learn the fundamentals of gene expression and its relationship to the architecture of genes and the genome. Next, you will be introduced to the fundamentals of genomic variation, including the various ways it can be classified and its frequency. Lastly, you will apply what you have learnt to interpret genotype and/or phenotype information for the prediction of disease risk, presentation and/or mechanisms.

This module aims to give you a fundamental understanding of DNA structure, function, and variation and recognise its importance to human health and disease. It will prepare you for further modules in genomic medicine that enable a deeper exploration of how genomic information can be used to improve healthcare, medicine, and our biological understanding of human diseases.

View an example full module specification

HPDM042: Research Project - Data

In this module you will apply and extend your existing knowledge and skills by undertaking an independent research project aligned with your degree programme (MSc Neuroscience, Health Data Science or Genomic Medicine). Projects are selected from a diverse portfolio designed to reflect a wide range of scientific interests and programme specialities. Depending on your programme, projects may involve laboratory-based research, a systematic review, or in silico approaches such as data analysis, computer modelling or bioinformatics. Projects are undertaken within Exeter’s leading research groups and may include collaboration with partners including the National Health Service, pharmaceutical companies and health data organisations.

View an example full module specification

HPDM043: Research Project - Literature

The aim of this module is for you to build on your previous knowledge, skills and experience of conducting research by undertaking a medical genomics research dissertation. The dissertation will demonstrate originality in the application of knowledge, together with a practical understanding of how established techniques of research and enquiry are used to create and interpret knowledge in a specialism of healthcare science. The research project will be designed to take into account the research training required by you and the needs of the department in which you will be conducting your research. Your research dissertation will be presented in the form of an in depth literature based review on a specific subject e.g. cardiovascular genomics or epigenetics.

You will use both the theoretical knowledge you will acquire, throughout the taught part of the course, and the analytical skills you will develop in order to participate in research independently. Undertaking of the research dissertation will involve formulating the research question, analysing published data, presenting results and providing a discussion of the results. The project could be carried out in the hosting NHS laboratory, research department or industry, under joint supervision i.e. involving tutors from both the hosting department and the MSc programme.

View an example full module specification

Optional modules

CodeModuleCredits
Optional 1
Application of Genomics in Infectious Disease15
Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment15
Pharmacogenomics and Stratified Healthcare15
Bioinformatics, Interpretation and Data Quality Assurance in Genome Analysis15
Ethical, Legal and Social Issues in Applied Genomics15
Counselling Skills for Genomics15
Advanced Bioinformatics15
Epigenetics15
Health Economics15

BIOM567: Application of Genomics in Infectious Disease

This module provides an exciting learning opportunity at the forefront of modern biology. You will explore the genomics of infectious agents, including the implications of gain/loss of genes and plasmids upon the pathogenicity and the sensitivity to drug treatment.

You will explore some of the huge range of freely available sequence data and computational tools that underpin modern genomics research.

This module is primarily aimed at clinical practitioners, diagnostic service providers, scientists, researchers and those aspiring to specialise within an academic career pathway. You will learn from, with and about your peers, developing a mutual understanding and respect for the positive contributions that each will bring to Genomic Medicine.

Computer-based practical workshops will consolidate the use of bioinformatics tools and databases through hands-on analysis of genomics data (e.g. comparative genomics of pathogen genome sequences or prediction of antimicrobial resistance).

Key employability skills include extracting and analysing complex information from web-based resources, and awareness of data-driven decision making. You will develop skills relevant to careers in medicine, medical research, and biosciences more broadly.

View an example full module specification

HPDM038: Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

This module covers the molecular mechanisms that underlie cancer development, growth and metastasis, and the differences between cancer types. It will explore the varied molecular and cellular actions of cancer treatments, the genomic factors affecting response and resistance to treatment and the research approaches to cancer drug development. The genomic basis for cancer predisposition will also be discussed, considering how this may impact patients and their families. This will include risk assessment, cancer screening, treatment and cancer preventative options.

The module aims to equip you with knowledge and understanding of the molecular mechanisms involved in cancer development and highlight how interrogation of a person’s own genome and the genome of neoplastic cells can facilitate the diagnosis and personalised treatment of cancer.

View an example full module specification

HPDM039: Pharmacogenomics and Stratified Healthcare

Pharmacogenomics and stratified healthcare should ensure that patients are offered the 'right treatment, for the right person, at the right time’. This module will provide you with an overview of the analytical strategies and techniques used in pharmacogenomics and explore some of the challenges and limitations in this field. It will consider current clinical practice as well as emerging technologies.

This module aims to describe the complexity of pharmacogenomics and its application in clinical practice. This will include tailoring drug treatment to improve patient response, and techniques to stratify patients at risk of adverse drug reactions. The module will use examples of known, validated pharmacogenomic tests, relevant to the use of drug treatments.

View an example full module specification

HPDM041: Bioinformatics, Interpretation and Data Quality Assurance in Genome Analysis

One of the key challenges in genomic medicine is to interpret large-scale sequencing data effectively in order to arrive at an accurate genetic diagnosis. The aim of this module is to provide you with an in-depth understanding of how this process is conducted. You will learn how large-scale genomic data is analysed and interpreted, as well as develop a practical understanding of how bioinformatic and statistical tools are used.

The module will cover the fundamental principles of bioinformatics and data quality assessment as applied to clinical genomics. You will use a range of software packages and in silico prediction tools, alongside genomic and clinical databases. You will learn how to apply these tools to evaluate the quality of a sequencing data set, align sequencing reads to a reference genome, identify genetic variants, and filter variants with evidence of pathogenicity. Theoretical sessions will be coupled with practical workshops and self-paced assignments, where you will get to perform a range of data bioinformatic analyses on real-world data.

By the end of the module, you will be able to use bioinformatic tools to critically interpret real-world data and to accurately report your findings in a diagnostic context.

View an example full module specification

HPDM044: Ethical, Legal and Social Issues in Applied Genomics

This module is available via blended learning with contact days on-campus and additional resources and activities via our online platform.

The module will provide you with a framework for ethical understanding of medical genomics. An 'ethics in practice' approach will be taken. You will be provided with a platform of ethical understanding from which to consider issues of confidentiality, autonomy, disclosure, informed consent and justice. You will consider the impact of genomic technologies on individuals, families, and demographic groupings. The social implications of genetic testing and screening will be considered, especially in the context of reproductive technologies. Finally, you will be provided with a legal framework for the use of genetic data for research, diagnostic and therapeutic purposes.

Many genomic tests have wider implications for the patient and their family, particularly where these may have a predictive aspect, provide incidental information, and/or have potential for being misleading or increase uncertainty. You will explore the ethical, legal and social implications (ELSI) involved in genomic testing and in specific integrated pathways.

View an example full module specification

HPDM045: Counselling Skills for Genomics

This module equips you with knowledge and skills to support patients undergoing genomic investigations. Working together through a mixture of lectures, discussions and practical group exercises, you build foundational counselling skills and learn how to apply them to different genomic scenarios. The course also introduces key practical tasks in the medical genomic pathway, including taking consent, interpreting results and documenting family history. Throughout the course we consider the social, personal and familial impact of these tests, exploring how we can support individuals and promote equity in genomic medicine.

Expect to be supported, challenged and to work together extensively in small groups. If you have any access needs that you would like to discuss, please contact the module lead. Due to the interactive and layered design of the course, attendance is essential for all four contact days.

View an example full module specification

HPDM046Z: Advanced Bioinformatics

This module is available either via blended learning with contact days on-campus, or as fully distance learning via our online platform. There may be some variation in scheduled teaching and learning activities depending on your mode of study.

The main challenge for application of genomic data is in its analysis and interpretation. In this module you will build on the knowledge and understanding gained in the Bioinformatics, Interpretation, Statistics and Data Quality Assurance module. You will learn how to use programming and scripting via the command line as well as the 'Galaxy' interface to formulate more complex research questions and analyse NHS data sets. You will gain a greater understanding of the different approaches to sequence data assembly and alignment and copy number variant and structural variant analysis.

The module will cover more advanced principles of informatics and bioinformatics applied to clinical genomics, how to find major genomic and genetic data resources for use in more complex data analysis, and use of programming and scripting via the command line. Theoretical sessions will be coupled with practical assignments of analysing and annotating predefined data sets. Upon completion of this module you will be eligible to base your MSc research project on data from the '100,000 Genomes Project'.

View an example full module specification

HPDM049: Epigenetics

This module is delivered through a blended learning format with scheduled on-campus contact days, supported by online learning resources available through the University’s virtual learning platform. The module introduces the structure and function of the human epigenome, including key regulatory mechanisms such as DNA methylation, histone modification and chromatin remodelling, and their role in controlling gene expression. You will examine how the epigenome interacts with the genome and how epigenetic regulation contributes to normal cellular function. Building on these core principles, the module explores the role of epigenetic variation in human health and disease. You will investigate how the epigenome changes with ageing and in response to environmental and psychosocial exposures, and how these changes may influence disease risk and progression. The application of epigenetics in diagnosis, treatment and monitoring of disease, particularly in areas such as cancer, will also be examined. The module will also introduce the genomic technologies and bioinformatics approaches used to study the epigenome, highlighting how epigenomic data can contribute to understanding disease mechanisms. Throughout the module, current challenges and limitations in epigenetic research will be critically discussed, alongside emerging developments in the field.

View an example full module specification

HPDM220Z: Health Economics

The continuous growth in the use of genomic technologies alongside other emerging healthcare innovations has led to many health advancements, but also has cost implications. Using established health economic methods, especially economic evaluation, it is possible to predict the costs of new treatments and the potential benefits to patients, the NHS and the wider economy in the context of the available resources for healthcare.

This module explores the potential impact of genomic medicine and other healthcare technologies on the healthcare system, its patients and their families. The health economic approach of economic evaluation methods will be used to demonstrate to you the potential costs and benefits of new clinical and technological approaches.

View an example full module specification

Please note that the module information displayed here is subject to change.

The PG Diploma comprises 120 credits made up of any modules of your choice.

Please note that the module information displayed here is subject to change.

The PG Certificate comprises 60 credits made up of any modules of your choice.

Entry requirements

Standard entry 

Normally a minimum 2:2 Honours degree (or equivalent) in a relevant discipline. Relevant clinical or professional experience may be taken into consideration as evidence of equivalency.  A personal statement, detailing your reasons for seeking to undertake this subject, will be required. 

The University is committed to an equal opportunities policy with respect to gender, age, race, sexual orientation and/or disability when dealing with applications. It is also committed to widening access to higher education to students from a diverse range of backgrounds and experience.

International students

Please visit our international equivalency pages to enable you to see if your existing academic qualifications meet our entry requirements.

International students are normally subject to visa regulations which prevent part-time study. It is recommended that international students apply for the level of the final award you intend to complete i.e. PGCert, PGDip or Masters, due to the associated cost and requirements for a Tier 4 student Visa.

Accreditation of prior learning for Masters courses in Healthcare and Medicine

Accreditation of Prior Learning (APL) is a process whereby students, who have already gained relevant skills and knowledge prior to the start of their course, may be granted a partial credit exemption from their programme instead of unnecessarily repeating work.

Find out more about APL

Please also see our guidance on essential documentation required for an initial decision on taught programme applications.

Entry requirements for international students

Please visit our entry requirements section for equivalencies from your country and further information on English language requirements.

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Please also see our guidance on essential documentation required for an initial decision on taught programme applications.

Entry requirements for international students

English language requirements

International students need to show they have the required level of English language to study this course.

The required IELTS test scores for this course fall under Profile B2.

Please visit our English language requirements page to view the required test scores and equivalencies from your country.

I was attracted to the flexibility of this course; I work as a Healthcare Assistant & for the COVID-19 immunisations program. I love that Exeter’s course allows me to work alongside study. I really like the course, everything varied & we choose quite a few modules. You get the breadth of genomics but also go into depth with each module to really develop your area of interest.

Hannah

Studying MSc Genomic Medicine

Hannah

Fees

 2026/27 entry 

Fees are subject to an annual increment each academic year.

UK fees

  • MSc: £12,200 full-time; £6,100pa part-time (2 years); £4,100pa part-time (3 years)
  • PGDip: £4,450pa (2 years)
  • PGCert: £4,450 (1 year)

Standalone module fees: UK: £1,300 per 15-credit module

Credit bearing modules: If you opt to take a non-accredited module and wish to then fully accredit this with the University of Exeter, you will need to pass the assessed elements of the course within 6 months of completion and there is an additional £200 accreditation fee.

International fees 

  • MSc: £28,900 full-time; £14,450pa part-time (2 years); £9,650pa part-time (3 years)
  • PGDip: £10,400 pa (2 years)
  • PGCert: £10,400 (1 year)

Standalone module fees: International £2,850 per 15-credit module

Scholarships

The University of Exeter offers a wide range of scholarships to support your education, with £7 million available for international students applying to study with us in the 2026/27 academic year, including our prestigious Exeter Excellence Scholarships. We also provide awards for sport, music and other achievements, as well as regional and partner scholarships with organisations such as Chevening, The Beacon Trust and the British Council. For more information on scholarships and other financial support, please visit our scholarships and bursaries page.

University of Exeter Alumni Scholarship

We are pleased to offer the University of Exeter Alumni Scholarship, a scholarship for University of Exeter alumni beginning a standalone postgraduate programme in 2026/27 with us a scholarship worth 20% of the cost of your first year tuition fees.

Terms and conditions, including deadlines, apply.

Funding and scholarships

There are various funding opportunities available including Global excellence scholarships. For more information visit our Masters funding page.

UK government postgraduate loan scheme

UK students studying one or two year variants of this programme may be eligible for a Postgraduate Master’s Loan. More information can be found on the government website.

Funding for NHS professionals

We are delighted to be one of six Higher Education Institutions contracted to deliver the MSc Genomic Medicine for NHS England (NHSE). As a result, NHS professionals working in England may apply for NHSE funding to support their study, following acceptance onto the MSc Genomic Medicine at the University of Exeter.

In the first instance, applicants may be funded for up to four modules, equivalent to a Postgraduate Certificate. Subject to successfully passing these modules you will be able to apply for further funding to complete either a Postgraduate Diploma or full MSc if you choose to do so. Please note that funding is limited and allocated on a first-come, first-served basis, as each institution is assigned a fixed number of funded modules per annum. We liaise with NHSE and endeavour to let students know the funding outcomes over the summer, prior to the MSc starting at the end of September. Please note to be eligible for this funding you must:

  • Have a permanent contract working in NHS England.
  • Have approval from your line manager to study for this course. NHSE will expect a written confirmation from your manager that confirms how the training aligns with local or regional workforce plans and how the knowledge gained will be applied in practice. 

Once you have applied to study Genomic Medicine with us, and received an offer, we will contact you with further details of how to express your interest in this funding.

More details of the NHSE Genomic Medicine funding can be found here.

Scholarships

Details of scholarships, including our Global Excellence scholarships for international fee paying students, can be found on our dedicated funding page.

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Knowing I had won this scholarship made me feel that the University was with me throughout my education.

Dugyu

MSc Genomic Medicine and PhD (Department of Clinical and Biomedical Sciences)

Dugyu

Teaching and research

We deliver transformative education that tackles health challenges of national and global importance.

Research

Our expertise ranges from translating findings from genomic studies to improve patient care, to using genomics to understand the evolution of infectious disease and the social and ethical aspects of genomic innovation in the life sciences, health and medicine.

Genomics research at Exeter is world-leading and supports our educational strategy and our objective to develop and apply innovative research and training methods, with opportunities for undergraduate, postgraduate and work-placed learning in diverse fields ranging from bioinformatics to the ethical legal and social impact of genomics.

Teaching

Using a mix of learning formats, our modules each run over a six- to eight-week period and include at least six half days of intensive face-to-face teaching, interspersed with distance learning and independent study.

Learning

All learning will be patient focused, using clinical scenarios and a variety of learning and teaching methods to promote a wide range of skills and meet differing learning styles, including seminars, group work, practical demonstrations and exercises surrounding interpretation of data.

Teaching will be delivered by experts from a range of academic and health care professional backgrounds chosen to ensure a breadth and depth of perspective and giving a good balance between theories and principles, and practical management advice.

Distance Learning

Distance learning is delivered through a virtual learning environment, delivering a library of study materials including recordings of all live lectures, virtual patients and independent learning tasks, reference materials and links to online tutorials.

There is an opportunity to undertake a research module either using genomic data from either the 100,000 Genomes project or our in-house data, or a literature-based dissertation.

Facilities

This programme is based at the St Luke’s campus in Exeter, just a 15 minute walk from the city centre and just over a mile away from the Streatham Campus. The campus is close to the Royal Devon and Exeter Hospital and RILD building, which is home to the NHS funded Exeter Health Library. Students have studied at St Luke’s campus for over 150 years and the campus enjoys a vibrant atmosphere set around the lawns of the quadrangle. Facilities at St Luke’s campus include:

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Pre-learning

Free online course: 'Genomic Medicine: Transforming Patient Care in Diabetes': This free online course will introduce the topic of genomics, using the University of Exeter’s research expertise in diabetes, to illustrate the clinical application of current genomics knowledge. Find out more

Before the start of your course please use this material as an introduction to some of the basic concepts in genomics. If there are gaps in your knowledge please use the learning resources provided below.

By the end of this pre-learning you should be able to:

  1. Describe how the genome is structured and organised; using terms such as DNA, nucleotide, gene and chromosome.
  2. Explain how the information encoded in DNA is decoded resulting in the production of proteins; using terms such as codon, mRNA, transcription, translation and tRNA.
  3. Explain how a genetic variant can result in an observable trait; using terms such as gene expression, genotype, mutation, phenotype and protein function.
  4. Use pedigree charts to deduce common modes of Mendelian inheritance; using terms such as allele, autosomal dominant, autosomal recessive, carrier, homozygote and X-linked.
  5. Appreciate that environmental factors affect gene expression. Terms to be understood here include epigenetics, histone and methylation.
  6. Understand that common diseases result from a complex interplay involving multiple genes and environmental factors. Terms to be understood here include polygenic and single nucleotide polymorphism (SNP).

Links and resources

All of these topics will be covered in more depth in the various modules, but you should have broad knowledge of the terms involved. To assist you in reaching these targets the following links and resources should be useful. Numbers in brackets refers to the intended learning outcome (numbered 1-6 above) that the resource will help you to understand.

The Genomics Education Programme, set up by the NHS to educate its staff, provides brief courses in their Genomics 101 collection (duration ~30 min each) that will give you an overview of genomics from a clinical perspective. 

To access these courses you will need to register for a free ‘elearning for healthcare’ account. On one of the course pages, select the ‘Sign up for free (NHS and UK universities)' option and register with a personal email account (this will give you access to limited content including the courses listed below).

yourgenome.org is produced by the Public Engagement team at the Wellcome Genome Campus near Cambridge. This website covers everything from basic biology to the complex ethical issues that arise from genome sequencing.

The Genetic Science Learning Center at The University of Utah is an internationally-recognised education program that translates science and health for non-experts. Particular recommendations include:

The DNA Learning Center is part of the world-renowned Cold Spring Harbor Laboratory which has been set up to educate students and non-experts as we enter an era where genetic information is available and plentiful.  Particular recommendations include:

FutureLearn offers many Massive Online Open Courses (MOOCs) generated in partnership with UK universities. Free to sign up to (for time-limited access for 4-5 weeks) and of particular relevance to this course are the following MOOCS:

The course text book, New Clinical Genetics (available online at the library). Using a case-based approach this textbook makes understanding genetics an attractive and stimulating experience.  

  • Chapters 1, 2, 3, 6, 11 & 13 will help you in reaching the intended objectives (1-6) for this part of the course.  There is also a good glossary at the back of the book.  Of course there is a lot of detail in these chapters that will be covered during the course, so don't feel you have to read and understand everything! 

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Careers

Who is this course for?

Students who study this programme are likely to be clinical practitioners, diagnostic service providers, scientists, researchers and those aspiring to specialise within an academic career pathway. The course is designed for healthcare professionals working within the NHS, to improve their capabilities and support career progression.

Students will gain an in-depth understanding of the current state of genomics knowledge and how it will bring benefit to patients through improved diagnosis and personalised treatment, and how to disseminate knowledge to peers, patients and the public.

Career paths

Students who are not healthcare professionals would acquire knowledge, understanding and skills that should help them gain employment or PhD positions, especially in the expanding fields of genomics, bioinformatics, or other medically-related research and development in either academia, pharmaceutical or biotech industries.

Careers support

All University of Exeter students have access to the Career Zone, which gives access to a wealth of business contacts, support and training as well as the opportunity to meet potential employers at our regular Careers Fairs.