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Understanding the role of bacterial anti-MGE defences to inform antimicrobial therapies

A talk about the evolutionary ecology of anti-MGE defences

A talk about the evolutionary ecology of anti-MGE defences (particularly CRISPR-Cas), and the counterdefence strategies that MGEs have evolved in return.


Event details

Professor Stineke Van Houte
Principal Investigator and BBSRC Future Leader Fellow, University of Exeter

Bacteria have evolved a range of mechanisms to defend themselves from infections by mobile genetic elements (MGEs), such as bacteriophages and plasmids. I will talk about the evolutionary ecology of anti-MGE defences (particularly CRISPR-Cas), and the counterdefence strategies that MGEs have evolved in return. I will then talk about how we can harness these fundamental insights into the development of new therapies to combat AMR in bacterial pathogens.

Host: Dr Ben Temperton (b.temperton@exeter.ac.uk)

Location:

LSI Seminar Room A and B