The Mental Health Research Group Seminar with Professor Seth Love
|A Medicine seminar|
|Date||23 January 2014|
|Time||13:00 to 14:00|
|Place||EMS Building G18 |
Lecture Theatre PMS G18, Medical School,St Luke’s Campus, Magdalen Road, Exeter EX1 2LU
Seth Love is the Director of the South West Dementia Brain Bank and Director of the MRC UKI Brain Banks Network and also Professor of Neuropathology at Bristol University.
Reduced cerebral blood flow is a major risk factor for dementia. It causes additive brain damage and in some forms of dementia contributes to the underlying neurodegenerative disease processes. Although some of the hypoperfusion in dementia is attributable to structural changes to blood vessels (including arteriosclerotic small vessel disease and cerebral amyloid angiopathy) and to reduced metabolic demand, much results from disturbances of vascular function. In this talk I shall discuss the post-mortem measurement of myelin proteins and mediators of vascular function as a means of assessing physiological and pathological processes involved in the regulation of cerebral perfusion. I shall also present data on the diverse ways in which abnormal regulation of vascular contractility contributes to grey and white matter hypoperfusion in Alzheimer’s disease, dementia with Lewy bodies and vascular dementia.
For further information please contact Wendy Cowell: email@example.com
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