Dr Stefano Pagliara
Living Systems Institute
Living Systems Institute, University of Exeter, Stocker Road, Exeter, EX4 4QD
My research is focused on understanding how microbial cells interact with their environment both as a community and as individual cells with an emphasis on AMR. Besides standard microbiology techniques and omics approaches, we develop bespoke microfluidic devices that enable us to accurately control the microenvironment surrounding the cells and perform a series of functional assays on the very same cell. This allows us to shed light on the physiology of rare subpopulations of phenotypically resistant cells that are generally hidden in ensemble measurements on clonal populations.
Understanding antibiotic uptake and efficacy in single cells via microfluidics and omics
Royal Society Single-cell Ecology 2018