Biosciences Research Seminar - The role of macrophage in Cryptococcus infection

The research in the lab mainly focuses how opportunistic fungal infections in immunocompromised people, in particular Cryptococcus species. Cryptococcus is a human pathogen and causes hundreds of thousands of deaths in the severely immunocompromised world-wide each year. We want to understand the fundamental process of how immune system functions during the infection and how macrophage mediated immunity play a role during Cryptococcus infection and the mechanism of phagocytosis of these opportunistic fungi.  We use a multidisciplinary approach to understand the infection mechanism and the regulation of the uptake mechanism of fungi.